Search Results - "Solvason, Nanette"
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Nursing Academic Leadership: An Urgent Workforce Shortage in Nursing Education
Published in Nursing education perspectives (01-09-2021)“…Abstract AIM The aim of the study was to describe the California nursing academic leader workforce shortage, identify succession planning activities, analyze…”
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Improved Efficacy of a Tolerizing DNA Vaccine for Reversal of Hyperglycemia through Enhancement of Gene Expression and Localization to Intracellular Sites
Published in The Journal of immunology (1950) (15-12-2008)“…Insulin is a major target for the autoimmune-mediated destruction of pancreatic beta cells during the pathogenesis of type I diabetes. A plasmid DNA vaccine…”
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Preclinical validation of anti-TMEFF2-auristatin E–conjugated antibodies in the treatment of prostate cancer
Published in Molecular cancer therapeutics (01-08-2004)“…Current treatments for advanced stage, hormone-resistant prostate cancer are largely ineffective, leading to high patient mortality and morbidity. To fulfill…”
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Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development
Published in International immunology (01-05-2000)“…Progression into G1 in B lymphocytes is regulated by cyclins D2 and D3, components of the cell cycle machinery currently believed to have overlapping and…”
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CD38: a new paradigm in lymphocyte activation and signal transduction
Published in Immunological reviews (01-02-1998)“…CD38 is a type II transmembrane glycoprotein that is extensively expressed on cells of bematopoietic and non‐hematopoietic lineage. Although the intracellular…”
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Nursing Academic Leadership: An Urgent Workforce Shortage in Nursing Education
Published in Nursing education perspectives (17-06-2021)Get full text
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Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes
Published in Science translational medicine (26-06-2013)“…In type 1 diabetes (T1D), there is an intense inflammatory response that destroys the β cells in the pancreatic islets of Langerhans, the site where insulin is…”
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Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells
Published in The Journal of experimental medicine (06-04-1998)“…Mutations in the tyrosine kinase, Btk, result in a mild immunodeficiency in mice (xid). While B lymphocytes from xid mice do not proliferate to…”
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The Earliest T Lineage–Committed Cells Depend on IL-7 for Bcl-2 Expression and Normal Cell Cycle Progression
Published in Immunity (Cambridge, Mass.) (01-07-1997)“…Interleukin-7 (IL-7)–deficient mice exhibit an early defect in lymphopoiesis. We examined Bcl-2 expression and the cell cycle status of immature thymocyte…”
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Chemokines in autoimmune diseases
Published in Immunological reviews (01-10-2000)“…Autoimmune diseases like multiple sclerosis (MS) and insulin-dependent diabetes (IDD) are believed to be mediated by pathogenic CD4+ autoreactive T cells which…”
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Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes
Published in The Journal of experimental medicine (01-08-1996)“…Progression through the cell cycle is a tightly controlled process that integrates signals generated at the plasma membrane with the proteins that form the…”
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An embryonic source of Ly1 but not conventional B cells
Published in International immunology (01-06-1991)“…Ly1+ B cells differ from conventional B cells with respect to their anatomical localization, cell surface marker expression, and antibody repertoire suggesting…”
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The human fetal omentum : a site of B cell generation
Published in The Journal of experimental medicine (01-02-1992)“…The fetal mouse omentum has been shown to be a source of precursors that exclusively reconstitutes Ly1+ B cells and the closely related Ly1- sister population,…”
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Chemokines in autoimmune diseases: Chemokines
Published in Immunological reviews (2000)Get full text
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The Role of CD4 and CD8 T cells in the Development of Autoimmune Diabetes
Published in Journal of autoimmunity (01-11-1999)“…The NOD mouse is a highly inbred mouse strain that spontaneously developed autoimmune diabetes, and provides an excellent model for the human form of…”
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A Conformationally-Constrained MHC Class II I-A-Derived Peptide Protects NOD Mice from the Development of Diabetes
Published in Journal of autoimmunity (01-06-1999)“…Allele-specific peptide vaccination against disease-associated MHC class II molecules is a promising new strategy for modulating self-antigen presentation to…”
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Signaling through murine CD38 is impaired in antigen receptor-unresponsive B cells
Published in European journal of immunology (01-05-1995)“…CD38 is a 42-kDa membrane associated enzyme which converts NAD into cyclic ADP-ribose (cADPR), a Ca(2+)-mobilizing second messenger, and ADP-ribose (ADPR)…”
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The fetal omentum in mice and humans. A site enriched for precursors of CD5 B cells early in development
Published in Annals of the New York Academy of Sciences (04-05-1992)“…From these studies the fetal omentum appears to be an important site of B-cell generation in humans and a source of CD5 B cells in mice. We have analyzed the…”
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A Conformationally-Constrained MHC Class II I-Ag7-Derived Peptide Protects NOD Mice from the Development of Diabetes
Published in Journal of autoimmunity (01-06-1999)“…Allele-specific peptide vaccination against disease-associated MHC class II molecules is a promising new strategy for modulating self-antigen presentation to…”
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