Search Results - "Soltan, Osama M."

Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in silico insights by Hamdi, Abdelrahman, Yaseen, Muhammad, Ewes, Wafaa A., Bhat, Mashooq Ahmad, Ziedan, Noha I., El-Shafey, Hamed W., Mohamed, Ahmed A. B., Elnagar, Mohamed R., Haikal, Abdullah, Othman, Dina I. A., Elgazar, Abdullah A., Abusabaa, Ahmed H. A., Abdelrahman, Kamal S., Soltan, Osama M., Elbadawi, Mostafa M.

“…This research study describes the development of new small molecules based on 2,4-thiazolidinedione (2,4-TZD) and their aldose reductase (AR) inhibitory…”
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Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives by Shaykoon, Montaser Sh, Marzouk, Adel A., Soltan, Osama M., Wanas, Amira S., Radwan, Mohamed M., Gouda, Ahmed M., Youssif, Bahaa G.M., Abdel-Aziz, Mohamed

“…[Display omitted] •Two series of 1,2,4-triazole and 1,3,4-oxadiazole derivatives were designed and synthesized.•3a-b and 4a-b showed higher antitrypanosomal…”
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Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy by Soltan, Osama M., Shoman, Mai E., Abdel-Aziz, Salah A., Narumi, Atsushi, Konno, Hiroyuki, Abdel-Aziz, Mohamed

“…Protein kinases have grown over the past few years as a crucial target for different cancer types. With the multifactorial nature of cancer, and the fast…”
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Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation by Soltan, Osama M., Abdel-Aziz, Salah A., Sh. Shaykoon, Montaser, Osawa, Keima, Narumi, Atsushi, Abdel-Aziz, Mohamed, Shoman, Mai E, Konno, Hiroyuki

“…[Display omitted] •Synthesis and evaluation of 1,5-diarylpyrazole derivatives as potential dual inhibitors of EGFR/JNK-2 for possible anticancer activity.•5b…”
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Utility of Cilefa Pink B, a foodstuff dye as a fluoro-substrate in the devising of the first facile green Molecular-mass-Related Fluorescence Sensor for quantifying amlodipine in batched material and dosage forms; content uniformity evaluation by Abdulhafez Hamad, Ahmed, Saad Al-Farhan, Badriah, El Hamd, Mohamed A., Abdelrahman, Kamal S., Soltan, Osama M., Abdel-Aal, Mohamed A.A., Fouad, Ali, Mahdi, Wael A., Alshehri, Sultan, Soltan, Moustafa K.

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Design of Multi-Target drugs of HDACs and other Anti-Alzheimer related Targets: Current strategies and future prospects in Alzheimer’s diseases therapy by Soltan, Osama M., Abdelrahman, Kamal S., Bass, Amr K.A., Takizawa, Kazuki, Narumi, Atsushi, Konno, Hiroyuki

“…[Display omitted] •The HDACs ability to synergistically boost the performance of other anti-AD drugs, as well as the ease with which HDACs inhibitor cap group,…”
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Integration of a facile sustainable resonance Rayleigh scattering switchable-based system for feasible determination of centrophenoxine, a nootropic and antioxidant agent; application to crude materials and dosage forms by Abdulhafez Hamad, Ahmed, Mahdi, Wael A., Alshehri, Sultan, Soltan, Osama M., Abdelrahman, Kamal S., Abdel-Aal, Mohamed A.A., Saad Al-Farhan, Badriah, Maslamani, Nujud, Saleh, Safaa F., El Hamd, Mohamed A.

“…A simple scheming summarizing the planned method and giving overall picture about the article concerns, CPX-Erythrosine B coupled product suggested mechanism,…”
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A new application of isoindole fluorophore derivative in sitagliptin antidiabetic medication assay: Application to dosage forms and biological fluid evaluation by El Hamd, Mohamed A., Soltan, Osama M., Abdelrahman, Kamal S., Alsaggaf, Wejdan T., Abu‐hassan, Ahmed A.

“…Dipeptidyl peptidase‐4 enzyme suppressant is a unique category of oral antidiabetic medication. Sitagliptin (STG) is a perfect member of this category and is…”
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Application of a white and green spectrofluorimetric approach for facile quantification of amlodipine, a hypotensive drug, in batch materials, dosage forms, and biological fluids; content homogeneity testing by Alqarni, Abdulmalik M., Haredy, Ahmed M., Abdelrahman, Kamal S., Soltan, Osama M., Abdel‐Aal, Mohamed A. A., Alrofaidi, Mohammad A., Aalamri, Abdulwahab, Osman, Mhdia Elhadi, Alamri, Ahmed Awadh, Hamad, Ahmed Abdulhafez

“…The suggested study adheres to a particular protocol to ensure that the process is environmentally friendly and sustainable. It is worth mentioning that…”
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Factorial design-aided derivatization-free fluorimetric ultrasensitive assay of vonoprazan with application in uniformity of dosage units and plasma samples analysis: Comprehensive and comparative greenness and whiteness assessment by El Hamd, Mohamed A., El-Maghrabey, Mahmoud, Magdy, Galal, Soltan, Osama M., Abdelrahman, Kamal S., Obaydo, Reem H., Mahdi, Wael A., Alshehri, Sultan, Abu-hassan, Ahmed A.

“…[Display omitted] •A novel factorial design-optimized spectrofluorimetric method for vonoprazan without pre-derivatization.•Complex formation between…”
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Roth's switch-on fluoremetric probe for green tracking and quantifying of 1.4-dihydropyridine medication: Evaluation of greenness, whiteness, and blueness by El Hamd, Mohamed A., Soltan, Osama M., Abdelrahman, Kamal S., Fouad, Ali, Saleh, Safaa F., Obaydo, Reem H., Sallam, Sahar, Alshehri, Sultan, Mahdi, Wael A., Hamad, Ahmed Abdulhafez

“…Facile incorporation of a fluorescence-modulating moiety to decorate a molecular derivatized system for an ultrasensitive quantifying of an individual of…”
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