Search Results - "Soloviova, Kateryna"
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Synthesis of Furan-Annelated BINOL Derivatives: Acid-Catalyzed Cyclization Induces Partial Racemization
Published in Journal of organic chemistry (07-12-2018)“…In this account, we describe the synthesis of a series of BINOL-based bis- and trisphosphoric acids 11d/e/f, which commonly feature an unusual phosphoric acid…”
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2
A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response
Published in PLoS neglected tropical diseases (01-01-2019)“…The natural history of schistosome infection in the mammalian host is determined by CD4+ T helper responses mounted against different parasite life cycle…”
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3
Both perforin and FasL are required for optimal CD8 T cell control of autoreactive B cells and autoantibody production in parent-into-F1 lupus mice
Published in Clinical immunology (Orlando, Fla.) (01-09-2018)“…To test the relative roles of perforin (pfp) vs. FasL in CTL control of autoreactive B cell expansion, we used the parent-into-F1 model of murine…”
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4
B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: Feasibility and benefit
Published in Cellular immunology (01-07-2020)“…•B cell depleting agents show promise in human lupus.•The parent-into-F1 model induces B cell depletion by CD8 CTL in vivo.•NZB transfers into B/W (NZBàF1)…”
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Alkylated Aromatic Thioethers with Aggregation‐Induced Emission Properties—Assembly and Photophysics
Published in Chemistry, an Asian journal (15-03-2019)“…In this contribution, we present the synthesis and self‐assembly of alkylated thioethers with interesting photophysical properties. To this end, the emission,…”
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Both perforin and FasL are required for optimal CD8 T cell control of autoreactive B cells and autoantibody production in parent-into-F1 lupus mice1
Published in Clinical immunology (Orlando, Fla.) (22-06-2018)“…To test the relative roles of perforin (pfp) vs. FasL in CTL control of autoreactive B cell expansion, we used the parent-into-F1 model of murine…”
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7
Colored optical waveguides in self-assembled thiadiazole-based materials
Published in Dyes and pigments (01-04-2018)“…The photophysical features and waveguiding behavior of two series of thiadiazoles are reported. The different substitution patterns on the thiadiazole moiety…”
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8
Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β
Published in The Journal of immunology (1950) (15-01-2012)“…Leading hypotheses to explain helminth-mediated protection against autoimmunity postulate that type 2 or regulatory immune responses induced by helminth…”
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Front Cover: Alkylated Aromatic Thioethers with Aggregation‐Induced Emission Properties—Assembly and Photophysics (Chem. Asian J. 6/2019)
Published in Chemistry, an Asian journal (15-03-2019)“…Soft and shiny: A series of alkylated aromatic thioethers reveal aggregation‐induced emission properties with a strong solvatochromic effect. In addition,…”
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TNF but not IL-12 or interferon-alpha (IFN-a) plays a critical signal 3 role in in vivo CD8 cytotoxic T lymphocyte (CTL) maturation in the parent-into-F1 (P→F1) model. (126.7)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract In addition to TcR signaling and costimulation, CD8 T cells require a third signal to mature into CTL. In pathogen models, IFN-a and IL-12 serve as…”
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11
Lupus prone DBA/2 (DBA) CD4 T cells exhibit greater B cell help, poorer help for CD8 cytotoxic T lymphocytes (CTL) and induce more severe renal disease compared to B10.D2 CD4 T cells in parent-into F1 (P→F1) mice. (123.27)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract Transfer of parental B6 T cells into B6D2F1 (B6→F1) mice results in acute graft-vs- host disease (GVHD) due to donor CD8 CTL that eliminate host…”
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12
In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-versus-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor
Published in The Journal of immunology (1950) (01-05-2013)“…A third signal is required for maturation of effector CD8 CTL in addition to TCR and CD28 engagement. Inflammatory cytokines can provide a third signal;…”
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13
Intrinsic differences in donor CD4 T cell IL-2 production influence severity of parent-into-F1 murine lupus by skewing the immune response either towards help for B cells and a sustained autoantibody response or towards help for CD8 T cells and a down regulatory Th1 response
Published in The Journal of immunology (1950) (28-08-2015)“…Using the parent-into-F1 model of induced lupus and (C57Bl/6xDBA2) F1 mice as hosts, we compared the inherent lupus-inducing properties of the two parental…”
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14
In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-vs.-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor
Published in The Journal of immunology (1950) (22-03-2013)“…A third signal is required for maturation of effector CD8 CTL in addition to TCR and CD28 engagement. Inflammatory cytokines can provide a third signal however…”
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15
In vivo IL-4 prevents allo-antigen driven CD8+ CTL development
Published in Clinical immunology (Orlando, Fla.) (01-07-2017)“…Abstract IL-4 has been shown to suppress acute graft vs. host disease (GVHD) in irradiated hosts. Here we evaluated whether IL-4 suppresses acute GVHD in the…”
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16
Intrinsic Differences in Donor CD4 T Cell IL-2 Production Influence Severity of Parent-into-F1 Murine Lupus by Skewing the Immune Response Either toward Help for B Cells and a Sustained Autoantibody Response or toward Help for CD8 T Cells and a Downregulatory Th1 Response
Published in The Journal of immunology (1950) (01-10-2015)“…Using the parent-into-F1 model of induced lupus and (C57BL/6 × DBA2) F1 mice as hosts, we compared the inherent lupus-inducing properties of the two parental…”
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17
Enhancement of suboptimal CD8 cytotoxic T cell effector function in vivo using antigen-specific CD80 defective T cells
Published in The Journal of immunology (1950) (01-01-2011)“…T cell upregulation of B7 molecules CD80 and CD86 limits T cell expansion in immunodeficient hosts; however, the relative roles of CD80 separate from CD86 on…”
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18
Signaling through the TNF-R2 (p75) but not TNF-R1 (p55) is absolutely required for in vivo CTL maturation in parent-into-F1 mice. (34.4)
Published in The Journal of immunology (1950) (01-04-2010)“…Abstract The transfer of B6 splenocytes into normal BDF1 mice results in donor cytotoxic T lymphocytes (CTL) that eliminate host B cells by two weeks and is a…”
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19
Long lasting elimination of B cells in NZB/W F1 mice can be induced by NZB but not NZW parental CD8 CTL. (143.12)
Published in The Journal of immunology (1950) (01-04-2010)“…Abstract B cells are a target in current lupus therapy. In the parent-into-F1 (P->F1) model of induced murine lupus, lupus is prevented by donor anti-host…”
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20
Both perforin (pfp) and Fas ligand (FasL) contribute to control of autoreactive B cells and retard lupus like disease in parent-into-F1 mice. (143.45)
Published in The Journal of immunology (1950) (01-04-2010)“…Abstract The transfer of B6 splenocytes into BDF1 (B6->F1) mice results in donor anti-host cytotoxic T cell elimination of host B cells whereas transferring…”
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