Search Results - "Solouki, Sabrina"
-
1
ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (21-06-2017)“…Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine…”
Get full text
Journal Article -
2
Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells
Published in Nature communications (19-05-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text
Journal Article -
3
Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages
Published in Frontiers in immunology (19-11-2018)“…Type 1 regulatory CD4 T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress…”
Get full text
Journal Article -
4
Non-receptor tyrosine kinase signaling in autoimmunity and therapeutic implications
Published in Pharmacology & therapeutics (Oxford) (01-09-2019)“…Autoimmune diseases are characterized by impaired immune tolerance towards self-antigens, leading to enhanced immunity to self by dysfunctional B cells and/or…”
Get full text
Journal Article -
5
TCR Signal Strength and Antigen Affinity Regulate CD8 + Memory T Cells
Published in The Journal of immunology (1950) (01-09-2020)“…CD8 T cells play a critical role in adaptive immunity, differentiating into CD8 memory T cells that form the basis of protective cellular immunity. Vaccine…”
Get full text
Journal Article -
6
ITK regulates antigen-specific CD8+ T cell-derived IL-10 production and modulates influenza-induced pulmonary immunopathology
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Influenza (flu) infection is a leading cause of respiratory disease and death worldwide, causing 3-5 million cases of severe illness and more than…”
Get full text
Journal Article -
7
TCR signal strength and antigen affinity independently modulate CD8+ memory T cell development
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract CD8+ T cells play a critical role in adaptive immunity by maintaining the ability to differentiate into CD8+ memory T cells, which provide the basis…”
Get full text
Journal Article -
8
TCR signal strength and antigen affinity modulate CD8+ memory T Cell development
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract CD8+ T cells play a critical role in adaptive immunity by maintaining the ability to differentiate into CD8+ memory T cells. During an intracellular…”
Get full text
Journal Article -
9
ITK signaling regulates IL-10 production by CD8+ T cells and lung immunopathology during influenza infection
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of severe illness during the average flu season. Severe influenza infections are…”
Get full text
Journal Article -
10
ITK regulates IL-10 production by CD8+ T cells and lung immunopathology during influenza infection
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of severe illness during the average flu season. Severe influenza infections are…”
Get full text
Journal Article -
11
T Cell Receptor Signal Strength and Antigen Affinity Differentially Regulate CD8+ Memory T Cell Development
Published 01-01-2020“…CD8+ T cells play a critical role in adaptive immunity by maintaining the ability to differentiate into CD8+ memory T cells, which provide the basis of…”
Get full text
Dissertation -
12
ITK signaling via the Ras/IRF4 pathway regulates the development and function of type 1 regulatory T cells
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging T cell receptor (TCR), express high levels of the immunosuppressive…”
Get full text
Journal Article -
13
The prostaglandin D2 receptor CRTH2 suppresses epithelial cell responses during intestinal helminth infection
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Type 2 inflammation is required for expulsion of intestinal helminth parasites and is characterized by immune cell activation, type 2 cytokine…”
Get full text
Journal Article -
14
Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses
Published in Retrovirology (11-08-2016)“…8E5/LAV cells harbor a single HIV provirus, and are used frequently to generate standards for HIV genome quantification. Using flow cytometry-based in situ…”
Get full text
Journal Article