Search Results - "Solomon, Greg"
-
1
The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein
Published in Human molecular genetics (01-08-2005)“…The most common cause of primary autosomal recessive microcephaly (MCPH) appears to be mutations in the ASPM gene which is involved in the regulation of…”
Get full text
Journal Article -
2
The SPANX Gene Family of Cancer/Testis-Specific Antigens: Rapid Evolution and Amplification in African Great Apes and Hominids
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2004)“…Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes comprise a gene family with five known members (SPANX-A1, -A2, -B, -C, and…”
Get full text
Journal Article -
3
Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27
Published in Genome research (01-11-2005)“…Genetic linkage studies indicate that germline variations in a gene or genes on chromosome Xq27-28 are implicated in prostate carcinogenesis. The linkage peak…”
Get full text
Journal Article -
4
Isolation of a functional copy of the human BRCA1 gene by transformation-associated recombination in yeast
Published in Gene (30-05-2000)“…The BRCA1 gene, mutations of which contribute significantly to hereditary breast cancer, was not identified in the existing YAC and BAC libraries. The gene is…”
Get full text
Journal Article -
5
Inter‐Strain Variation in Mouse Mitochondrial Genome and Effects of Oxidative Stress
Published in The FASEB journal (01-04-2016)“…Abstract only Reactive oxygen species contribute to the pathogenesis of many acute and chronic pulmonary disorders, including bronchopulmonary dysplasia (BPD),…”
Get full text
Journal Article -
6
-
7
Genetic Determinants of Oxidant-Induced Nuclear and Mitochondrial DNA Lesions in a Neonatal Inbred Mouse Model of Acute Lung Injury
Published in Free radical biology & medicine (01-11-2014)Get full text
Journal Article -
8
Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families
Published in Genes chromosomes & cancer (01-10-2012)“…Several linkage studies provided evidence for the presence of the hereditary prostate cancer locus, HPCX1, at Xq27‐q28. The strongest linkage peak of prostate…”
Get full text
Journal Article -
9
Mutational analysis of SPANXGenes in families with X-linked prostate cancer
Published in The Prostate (01-06-2007)Get full text
Journal Article -
10
The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions
Published in Oncogene (24-01-2002)“…In this work, the full-length hTERT gene was isolated and the sequence of the previously unknown region in intron 6 as well as that of upstream and downstream…”
Get full text
Journal Article -
11
Mutational analysis of SPANX genes in families with X-Linked prostate cancer
Published in The Prostate (01-06-2007)“…BACKGROUND Previous genetic linkage studies identified a locus for susceptibility to prostate cancer called HPCX at Xq27. The candidate region contains two…”
Get full text
Journal Article -
12
Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast
Published in EMBO reports (01-03-2003)“…The reported draft human genome sequence includes many contigs that are separated by gaps of unknown sequence. These gaps may be due to chromosomal regions…”
Get full text
Journal Article -
13
A novel strategy for analysis of gene homologues and segmental genome duplications
Published in Journal of molecular evolution (01-06-2003)“…Transformation-associated recombination (TAR) cloning allows selective isolation of a desired chromosomal region or gene from complex genomes. The method…”
Get full text
Journal Article -
14
Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line
Published in Breast cancer research : BCR (01-01-2000)“…STATEMENT OF FINDINGS: We tested the hypothesis that BRCA1 may play a role in the regulation of ovarian tumor cell death as well as the inhibition of ovarian…”
Get full text
Journal Article -
15
Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines
Published in Molecular carcinogenesis (01-08-1996)“…p21/WAF1/CIP1/SDI1 is an important cell‐cycle mediator with tumor suppressor gene capabilities, and its inactivation could potentially lead to tumor…”
Get full text
Journal Article -
16
Mutational analysis of thep21/WAF1/CIP1/SDI1 coding region in human tumor cell lines
Published in Molecular carcinogenesis (01-08-1996)Get full text
Journal Article