Search Results - "Solomides, Charalambos"
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MicroRNA-663 Regulates Human Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Neointimal Formation
Published in Circulation research (25-10-2013)“…RATIONALE:Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of vascular disorders such as atherosclerosis and restenosis after…”
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The role of Nrf2 and ATF2 in resistance to platinum-based chemotherapy
Published in Cancer chemotherapy and pharmacology (01-02-2017)“…Purpose Nrf2 and its role in controlling levels of the AKR family of aldo–keto reductases which have been implicated in resistance to platinum-based…”
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Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity
Published in Cancer immunology research (01-02-2014)“…The majority of chimeric antigen receptor (CAR) T-cell research has focused on attacking cancer cells. Here, we show that targeting the tumor-promoting,…”
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Cisplatin resistance in human cervical, ovarian and lung cancer cells
Published in Cancer chemotherapy and pharmacology (01-06-2015)“…Purpose This study was performed to determine whether or not in cervical, ovarian and lung cancer cell lines, free radicals (ROS) play a role in cisplatin…”
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Human abdominal aortic aneurysm (AAA): Evidence for an autoimmune antigen-driven disease
Published in Autoimmunity reviews (01-10-2022)“…Abdominal aortic aneurism (AAA) is a complex immunological disease with a strong genetic component, and one of the ten leading causes of death of individuals…”
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IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling
Published in Molecular cancer research (01-07-2017)“…Insulin-like growth factor binding protein 3 (IGFBP3) modulates cell growth through IGF-dependent and -independent mechanisms. Reports suggest that the serum…”
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Resected WHO grade I meningioma and predictors of local control
Published in Journal of neuro-oncology (01-03-2021)“…Introduction Despite optimal surgical resection, meningiomas may recur, with increasing grade and the degree of resection being predictive of risk. We…”
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Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling
Published in The Journal of biological chemistry (07-10-2011)“…We have recently discovered that the insulin-like growth factor receptor I (IGF-IR) is up-regulated in human invasive bladder cancer and promotes migration and…”
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Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma
Published in Cancer (15-07-2012)“…BACKGROUND: The aim of this study was to evaluate the expression of epidermal growth factor receptor (EGFR) and insulinlike growth factor 1 receptor (IGF‐1R)…”
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Dietary Curcumin Increases Antioxidant Defenses in Lung, Ameliorates Radiation-Induced Pulmonary Fibrosis, and Improves Survival in Mice
Published in Radiation research (01-05-2010)“…The effectiveness of lung radiotherapy is limited by radiation tolerance of normal tissues and by the intrinsic radiosensitivity of lung cancer cells. The…”
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Radiation mitigating properties of the lignan component in flaxseed
Published in BMC cancer (04-04-2013)“…Wholegrain flaxseed (FS), and its lignan component (FLC) consisting mainly of secoisolariciresinol diglucoside (SDG), have potent lung radioprotective…”
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Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice
Published in BMC cancer (24-06-2011)“…Flaxseed (FS) is a dietary supplement known for its antioxidant and anti-inflammatory properties. Radiation exposure of lung tissues occurs either when given…”
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Cytohistologic correlation of basaloid salivary gland neoplasms: Can cytomorphologic classification be used to diagnose and grade these tumors?
Published in Cancer cytopathology (01-02-2020)“…Background Basaloid salivary gland neoplasms (BSNs), which include benign primary tumors and primary or metastatic malignancies, show overlapping morphology in…”
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Space radiation-associated lung injury in a murine model
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2015)“…Despite considerable progress in identifying health risks to crewmembers related to exposure to galactic/cosmic rays and solar particle events (SPE) during…”
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Chromogenic immunohistochemical quadruplex provides accurate diagnostic differentiation of non-small cell lung cancer
Published in Annals of diagnostic pathology (01-04-2020)“…Lung cancer is the most common cancer worldwide and has the highest mortality rate. Carcinomas comprise 95% of all lung malignancies, the vast majority of…”
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Sentinel Lymph Node Characterization with a Dual-Targeted Molecular Ultrasound Contrast Agent
Published in Molecular imaging and biology (01-04-2018)“…Purpose The purpose of this study was to assess the performance of molecular ultrasound with dual-targeted microbubbles to detect metastatic disease in the…”
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Contiguous verrucous proliferations in syringocystadenoma papilliferum: A retrospective analysis with additional evaluation via mutation‐specific BRAFV600E immunohistochemistry
Published in Journal of cutaneous pathology (01-03-2018)“…Background Syringocystadenoma papilliferum (SCAP) is an uncommon cutaneous adnexal proliferation. There have been several reports describing collision lesions…”
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A Single Dose of the Deactivated Rabies-Virus Vectored COVID-19 Vaccine, CORAVAX, Is Highly Efficacious and Alleviates Lung Inflammation in the Hamster Model
Published in Viruses (24-05-2022)“…Without sufficient herd immunity through either vaccination or natural infection, the coronavirus disease 2019 pandemic is unlikely to be controlled. Waning…”
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