Search Results - "Solmesky, Leonardo J."

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase by Amitai, Gabriel, Plotnikov, Alexander, Chapman, Shira, Lazar, Shlomi, Gez, Rellie, Loewenthal, Dan, Shurrush, Khriesto A., Cohen, Galit, Solmesky, Leonardo J., Barr, Haim, Russell, Alan J.

“…Government-sanctioned use of nerve agents (NA) has escalated dramatically in recent years. Oxime reactivators of organophosphate (OP)-inhibited…”
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Personalized drug discovery: HCA approach optimized for rare diseases at Tel Aviv University by Solmesky, Leonardo J, Weil, Miguel

“…The Cell screening facility for personalized medicine (CSFPM) at Tel Aviv University in Israel is devoted to screening small molecules libraries for finding…”
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A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease by Solmesky, Leonardo J, Khazanov, Netaly, Senderowitz, Hanoch, Wang, Peixiang, Minassian, Berge A, Ferreira, Igor M, Yue, Wyatt W, Lossos, Alexander, Weil, Miguel, Kakhlon, Or

“…Glycogen storage disorders (GSDs) are caused by excessive accumulation of glycogen. Some GSDs [adult polyglucosan (PG) body disease (APBD), and Tarui and…”
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Structural profiling and biological performance of phospholipid–hyaluronan functionalized single-walled carbon nanotubes by Dvash, Ram, Khatchatouriants, Artium, Solmesky, Leonardo J., Wibroe, Peter P., Weil, Miguel, Moghimi, S. Moein, Peer, Dan

“…In spite of significant insolubility and toxicity, carbon nanotubes (CNTs) erupt into the biomedical research, and create an increasing interest in the field…”
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Guaiacol as a drug candidate for treating adult polyglucosan body disease by Kakhlon, Or, Ferreira, Igor, Solmesky, Leonardo J, Khazanov, Netaly, Lossos, Alexander, Alvarez, Rafael, Yetil, Deniz, Pampou, Sergey, Weil, Miguel, Senderowitz, Hanoch, Escriba, Pablo, Yue, Wyatt W, Akman, H Orhan

“…Adult polyglucosan body disease (APBD) is a late-onset disease caused by intracellular accumulation of polyglucosan bodies, formed due to glycogen-branching…”
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Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1(G93A) mouse model by Lilo, Eitan, Wald-Altman, Shane, Solmesky, Leonardo J, Ben Yaakov, Keren, Gershoni-Emek, Noga, Bulvik, Shlomo, Kassis, Ibrahim, Karussis, Dimitrios, Perlson, Eran, Weil, Miguel

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder of motor neurons. Although most cases of ALS are sporadic (sALS) and of unknown…”
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Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: a high content analysis approach by Solmesky, Leonardo J, Shuman, Michal, Goldsmith, Meir, Weil, Miguel, Peer, Dan

“…Lipid-based nanoparticles (LNPs) are widely used for the delivery of drugs and nucleic acids. Although most of them are considered safe, there is confusing…”
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Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium by Solmesky, Leonardo J, Abekasis, Michal, Bulvik, Shlomo, Weil, Miguel

“…Bone marrow human mesenchymal stem cells (hMSCs) are known to survive in serum-free media, when most normal somatic cells do not survive. We found that the…”
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Preparation and epitope characterization of monoclonal antibodies suitable for detection of Tomato yellow leaf curl virus by Solmesky, Leonardo J, Zrachya, Avi, Denisova, Galina, Gafni, Yedidya, Gershoni, Jonathan M

“…Tomato yellow leaf curl virus (TYLCV) is a begomovirus that seriously threatens tomato crops worldwide. Current immunodiagnostic methods for this pathogen…”
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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids by Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., Roverts, Rona, Willemsen, Brigith, Beukenboom, Marcel, Dunnen, Wilfred den, Triana, Sergio H., Timm, Marie-Cherelle, van den Berge, Bartholomeus T., Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Grünberg, Katrien, Steenbergen, Eric J., Czogalla, Jan, Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Huber, Tobias B., Bar-David, Elad, Barr, Haim, Boby, Melissa L., Borden, Bruce, Bowman, Gregory R., Brun, Juliane, BVNBS, Sarma, Carbery, Anna, Chernychenko, Eugene, Clyde, Austin, Coffland, Joseph E., Cole, Jason, Cox, Lisa, Dudgeon, Tim, Dunnett, Louise, Erez, Noam, Fate, Gwen, Ferrins, Lori, Foster, Richard, Foster, Holly, Gabizon, Ronen, Gawriljuk, Victor O., Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glen, Robert, Gorichko, Marian, Griffen, Ed J., Heer, Jag, Hill, Michelle, Horrell, Sam, Jajack, Andrew, De Jonghe, Steven, Kantsadi, Anastassia L., Koekemoer, Lizbe, Lee, Alpha A., Lefker, Bruce A., Macdonald, Hannah Bruce, Maclean, Beth, McCorkindale, Willam, McGovern, Briana L., Michurin, Oleg, Morris, Aaron, Morris, Garret M., Neyts, Johan, Oliva, Glaucius, Overheul, Gijs J., Owen, David, Psenak, Vladimir, Pai, Ruby, Paran, Nir, Perry, Benjamin, Pingle, Maneesh, Politi, Boaz, Powell, Ailsa, Puni, Reut, Resnick, Efrat, Rosales, Romel, Schofield, Chris, Shafeev, Mikhail, Sittner, Assa, Skyner, Rachael, Spencer, John, Tamir, Hadas, Tennant, Rachael, Tumber, Anthony, van Rij, Ronald P., Voelz, Vincent, Volkamer, Andra, von Delft, Annette, White, Kris M., Wright, Nathan, Zidane, Hadeer, Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart

“…Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus. Here, we report that…”
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Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1G93A mouse model by Lilo, Eitan, Wald-Altman, Shane, Solmesky, Leonardo J., Ben Yaakov, Keren, Gershoni-Emek, Noga, Bulvik, Shlomo, Kassis, Ibrahim, Karussis, Dimitrios, Perlson, Eran, Weil, Miguel

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Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1 super(G93A) mouse model by Lilo, Eitan, Wald-Altman, Shane, Solmesky, Leonardo J, Ben Yaakov, Keren, Gershoni-Emek, Noga, Bulvik, Shlomo, Kassis, Ibrahim, Karussis, Dimitrios, Perlson, Eran, Weil, Miguel

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder of motor neurons. Although most cases of ALS are sporadic (sALS) and of unknown…”
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