Search Results - "Solmaz Sadeghi"
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Evaluation of eight formulas for LDL-C estimation in Iranian subjects with different metabolic health statuses
Published in Lipids in health and disease (28-12-2019)“…Considering the crucial role of low-density lipoprotein-cholesterol (LDL-C) concentration in determining cardiovascular risk, the accuracy of LDL-C estimation…”
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Identification of candidate genes and miRNAs for sensitizing resistant colorectal cancer cells to oxaliplatin and irinotecan
Published in Cancer chemotherapy and pharmacology (2020)“…Drug resistance to irinotecan and oxaliplatin, two widely used chemotherapeutic, has become a common problem in cancerous patients. Despite numerous valuable…”
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3
Sequence stratigraphy and microfacies of the Sarvak Formation, west of the Hendijan–Bahregansar–Nowrooz Palaeohigh
Published in Journal of stratigraphy and sedimentology researches (01-06-2023)“…AbstractThe Sarvak Formation is one of the most important oil reservoirs in southwestern Iran. The Hendijan–Bahregansar–Nowrooz strike-slip Fault (HBNF) is…”
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Rational design of DKK3 structure-based small peptides as antagonists of Wnt signaling pathway and in silico evaluation of their efficiency
Published in PloS one (24-02-2017)“…Dysregulated Wnt signaling pathway is highly associated with the pathogenesis of several human cancers. Dickkopf proteins (DKKs) are thought to inhibit Wnt…”
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Prediction of Computer Voyeurism and Stigma of the First Wave of the Coronavirus Disease-2019 Pandemic based on the Dimensions of Internet Addiction among Youth
Published in Pizishkī-i bālīnī-i Ibn-i Sīnā (01-09-2020)“…Background and Objective: Today, the Internet and Internet addiction are among the most important issues involving the young generation. Regarding the spread…”
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Effect of Health-promoting Lifestyle and Psychological Well-being on Anxiety Induced by Coronavirus Disease 2019 in Non-medical Students
Published in Majallah-i dānishgāh-i 'ulūm-i pizishkī-i Arāk (01-12-2020)“…Background and Aim: Anxiety is one of the clinical signs of viral diseases such as Coronavirus Disease 2019 (COVID-19), which can threaten the immune system…”
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Repurposing of the approved small molecule drugs in order to inhibit SARS-CoV-2 S protein and human ACE2 interaction through virtual screening approaches
Published in Journal of biomolecular structure & dynamics (02-02-2022)“…Most recently, the new coronavirus (SARS-CoV-2) has been recognized as a pandemic by the World Health Organization (WHO) while this virus shares substantial…”
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Plant macrofossils from the Shemshak Formation, Rudbar, western Alborz
Published in Journal of stratigraphy and sedimentology researches (01-12-2021)“…Abstract Plant macrofossils from the Shemshak Formation, Rudbar, western Alborz, collected at two distinct horizons, including horizon 1 (Koushk area) and…”
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Chondroitinase as a therapeutic enzyme: Prospects and challenges
Published in Enzyme and microbial technology (01-01-2024)“…The chondroitinases (Chase) are bacterial lyases that specifically digest chondroitin sulfate and/or dermatan sulfate glycosaminoglycans via a β-elimination…”
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Facies variation, sedimentary environments, and sequence stratigraphy of the Sarvak Formation adjacent to the Hendijan–Bahregansar and Kharg–Mish Palaeohighs, northwestern Persian Gulf
Published in Journal of stratigraphy and sedimentology researches (01-09-2024)“…AbstractThe northwestern part of the Iranian sector of the Persian Gulf (NWPG) is a highly significant hydrocarbon offshore area, located within the southern…”
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Keratinocyte growth factor in focus: A comprehensive review from structural and functional aspects to therapeutic applications of palifermin
Published in International journal of biological macromolecules (30-11-2021)“…Palifermin (Kepivance™) is the first therapeutic approved by the Food and Drug Administration for preventing and managing the oral mucositis provoked by…”
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Improved osteogenic differentiation of human induced pluripotent stem cells cultured on polyvinylidene fluoride/collagen/platelet‐rich plasma composite nanofibers
Published in Journal of cellular physiology (01-02-2020)“…Blood transfusion or blood products, such as plasma, have a long history in improving health, but today, platelet‐rich plasma (PRP) is used in various medical…”
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Production of CAR T-cells by GMP-grade lentiviral vectors: latest advances and future prospects
Published in Critical reviews in clinical laboratory sciences (18-08-2019)“…Chimeric antigen receptor (CAR) T-cells represent a paradigm shift in cancer immunotherapy and a new milestone in the history of oncology. In 2017, the Food…”
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14
In silico enhancement of the stability and activity of keratinocyte growth factor
Published in Journal of theoretical biology (07-04-2017)“…Keratinocyte growth factor (KGF), a member of the fibroblast growth factor (FGF) family, has been implicated in some biological processes such as cell…”
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In silico mutagenesis in recombinant human keratinocyte growth factor: Improvement of stability and activity in addition to decrement immunogenicity
Published in Journal of molecular graphics & modelling (01-06-2020)“…The recombinant human keratinocyte growth factor (rhKGF) is clinically applied to decrease the incidence and duration of cancer therapeutic agents…”
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Evaluation the potential of recombinant anti-CD3 nanobody on immunomodulatory function
Published in Molecular immunology (01-02-2020)“…•An anti-CD3 nanobody was constructed and successfully expressed.•The purified anti-CD3 nanobody recognize native CD3 expressed on the cells.•The purified…”
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Genetically modified immune cells targeting tumor antigens
Published in Pharmacology & therapeutics (Oxford) (01-10-2020)“…Immunotherapy approaches consisting of genetically modified immune cells have become a promising platform for cancer treatment. Such ‘living’ therapies…”
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Identification of new DNA gyrase inhibitors based on bioactive compounds from streptomyces: structure-based virtual screening and molecular dynamics simulations approaches
Published in Journal of biomolecular structure & dynamics (11-02-2020)“…DNA gyrase enzyme has vital role in bacterial survival and can be considered as a potential drug target. Owing to the appearance of resistance to…”
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In silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N-terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with low density lipoprotein receptor related protein 5/6
Published in Journal of biomolecular structure & dynamics (03-07-2019)“…Wnt (Wingless Int) signaling pathway has been known to be dysregulated in several human cancers, especially colorectal cancer (CRC). The Dickkopf (DKK) family…”
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Acceleration of osteogenic differentiation by sustained release of BMP2 in PLLA/graphene oxide nanofibrous scaffold
Published in Polymers for advanced technologies (01-01-2021)“…After about three decades of experience, tissue engineering has become one of the most important approaches in reconstructive medical research to treat…”
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