Search Results - "Sollie, Frans"

Absorption, Metabolism, and Excretion of Intravenously and Orally Administered [14C]Telmisartan in Healthy Volunteers by Stangier, Joachim, Schmid, Jochen, Türck, Dietrich, Switek, Heinz, Verhagen, Aalt, Peeters, Pierre A. M., van Marle, Sjoerd P., Tamminga, Wim J., Sollie, Frans A. E., Jonkman, Jan H. G.

“…The study was conducted in healthy male volunteers to evaluate the absorption, metabolic pattern, and mode of elimination of telmisartan, a nonpeptide…”
Get full text

The Effect of Telmisartan on the Steady-State Pharmacokinetics of Digoxin in Healthy Male Volunteers by Stangier, Joachim, Su, Chung-An P. F., Hendriks, Maarten G. C., van Lier, Jan J., Sollie, Frans A. E., Oosterhuis, Berend, Jonkman, Jan H.G.

“…A multiple‐dose, open‐label, two‐period, crossover randomized study was conducted in 12 healthy male volunteers to investigate the effect of multiple‐dose…”
Get full text

Steady-State Pharmacodynamics and Pharmacokinetics of Warfarin in the Presence and Absence of Telmisartan in Healthy Male Volunteers by Stangier, Joachim, Su, Chung-An P. F., Hendriks, Maarten G. C., van Lier, Jan J., Sollie, Frans A. E., Oosterhuis, Berend, Jonkman, Jan H. G.

“…The effects of multiple‐dose telmisartan on the steady‐state pharmacodynamics and pharmacokinetics of warfarin were assessed in 12 healthy young males in an…”
Get full text

The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers by Seaber, Emma J., Peck, Richard W., Smith, Deborah A., Allanson, John, Hefting, Nanco R., Van Lier, Jan J., Sollie, Frans A. E., Wemer, Johan, Jonkman, Jan H. G.

“…Aims Zolmitriptan (Zomig (formerly 311C90)) is a novel 5‐HT1B/1D receptor agonist developed for the acute oral treatment of migraine. A highly sensitive…”
Get full text

Single-dose subcutaneous administration of recombinant human parathyroid hormone [rhPTH(1-84)] in healthy postmenopausal volunteers by Schwieter, Hendrik Reinier, Groen, Edwin W. J., Sollie, Frans A. E., Jonkman, Jan H. G.

“…Background Parathyroid hormone [PTH(1–84)] is intended for treatment of osteoporosis because it stimulates new bone formation of normal structure and…”
Get full text

Development of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452 by Alleva, David G., Delpero, Andrea R., Scully, Melanie M., Murikipudi, Sylaja, Ragupathy, Ramya, Greaves, Emma K., Sathiyaseelan, Thillainaygam, Haworth, Jeffrey R., Shah, Nishit J., Rao, Vidhya, Nagre, Shashikant, Lancaster, Thomas M., Webb, Sarah S., Jasa, Allison I., Ronca, Shannon E., Green, Freedom M., Elyard, Hanne Andersen, Yee, JoAnn, Klein, Jeffrey, Karnes, Larry, Sollie, Frans, Zion, Todd C.

“…AKS-452 is a biologically-engineered vaccine comprising an Fc fusion protein of the SARS-CoV-2 viral spike protein receptor binding domain antigen (Ag) and…”
Get full text

A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452 by Feitsma, Eline A., Janssen, Yester F., Boersma, Hendrikus H., van Sleen, Yannick, van Baarle, Debbie, Alleva, David G., Lancaster, Thomas M., Sathiyaseelan, Thillainaygam, Murikipudi, Sylaja, Delpero, Andrea R., Scully, Melanie M., Ragupathy, Ramya, Kotha, Sravya, Haworth, Jeffrey R., Shah, Nishit J., Rao, Vidhya, Nagre, Shashikant, Ronca, Shannon E., Green, Freedom M., Aminetzah, Ari, Sollie, Frans, Kruijff, Schelto, Brom, Maarten, van Dam, Gooitzen M., Zion, Todd C.

“…Previous interim data from a phase I study of AKS-452, a subunit vaccine comprising an Fc fusion of the respiratory syndrome coronavirus 2 (SARS-CoV-2) spike…”
Get full text

Phase I interim results of a phase I/II study of the IgG-Fc fusion COVID-19 subunit vaccine, AKS-452 by Janssen, Yester F., Feitsma, Eline A., Boersma, Hendrikus H., Alleva, David G., Lancaster, Thomas M., Sathiyaseelan, Thillainaygam, Murikipudi, Sylaja, Delpero, Andrea R., Scully, Melanie M., Ragupathy, Ramya, Kotha, Sravya, Haworth, Jeffrey R., Shah, Nishit J., Rao, Vidhya, Nagre, Shashikant, Ronca, Shannon E., Green, Freedom M., Aminetzah, Ari, Sollie, Frans, Kruijff, Schelto, Brom, Maarten, van Dam, Gooitzen M., Zion, Todd C.

“…To address the coronavirus disease 2019 (COVID-19) pandemic caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a…”
Get full text

No pharmacokinetic or pharmacodynamic interaction between theophylline and the leukotriene biosynthesis inhibitor BAY x 1005 by Groen, H, Moesker, H L, Leeuwenkamp, O R, Sollie, F A, Jonkman, J H

“…An open, randomized, three-period crossover study was conducted to compare the steady-state pharmacokinetics, pharmacodynamics, and tolerability of concomitant…”
Get more information

The influence of caffeine on the steady-state pharmacokinetics of theophylline by Jonkman, J H, Sollie, F A, Sauter, R, Steinijans, V W

“…During this open, two-period crossover study in eight healthy volunteers, 1200 mg anhydrous theophylline was administered as a two-stage infusion during 24…”
Get more information

Pharmacokinetic modeling of the anticonvulsant response of oxazepam in rats using the pentylenetetrazol threshold concentration as pharmacodynamic measure by Dingemanse, J, Sollie, F A, Breimer, D D, Danhof, M

“…This investigation developed strategies along which the anticonvulsant effect of oxazepam in the rat could be pharmacokinetically modeled. After determination…”
Get more information

Steady-state pharmacodynamics and pharmacokinetics of warfarin in the presence and absence of telmisartan in healthy male volunteers: Clinical Pharmacology of Telmisartan by STANGIER, Joachim, SU, Chung-An P. F, HENDRIKS, Maarten G. C, VAN LIER, Jan J, SOLLIE, Frans A. E, OOSTERHUIS, Berend, JONKMAN, Jan H. G

Get full text

The effect of telmisartan on the steady-state pharmacokinetics of digoxin in healthy male volunteers: Clinical Pharmacology of Telmisartan by STANGIER, Joachim, SU, Chung-An P. F, HENDRIKS, Maarten G. C, VAN LIER, Jan J, SOLLIE, Frans A. E, OOSTERHUIS, Berend, JONKMAN, Jan H. G

Get full text

Absorption, metabolism, and excretion of intravenously and orally administered [14C]telmisartan in healthy volunteers: Clinical Pharmacology of Telmisartan by STANGIER, Joachim, SCHMID, Jochen, TÜRCK, Dietrich, SWITEK, Heinz, VERHAGEN, Aalt, PEETERS, Pierre A. M, VAN MARLE, Sjoerd P, TAMMINGA, Wim J, SOLLIE, Frans A. E, JONKMAN, Jan H. G

Get full text

A pharmacokinetic and pharmacodynamic comparison of metoprolol CR/ZOK with a conventional slow release preparation by Oosterhuis, B, Jonkman, J, Zuiderwijk, P, Sollie, F

“…The plasma concentration-time profile and hemodynamic effects of metoprolol after the administration of metoprolol CR/ZOK, a multiple-unit controlled release…”
Get more information