Search Results - "Soll, Steven J."
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Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication
Published in PLoS pathogens (01-01-2018)“…The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of viral replication, including transcription, splicing, nuclear…”
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Assisted evolution enables HIV-1 to overcome a high TRIM5α-imposed genetic barrier to rhesus macaque tropism
Published in PLoS pathogens (01-09-2013)“…Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon…”
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CG dinucleotide suppression enables antiviral defence targeting non-self RNA
Published in Nature (London) (05-10-2017)“…Vertebrate genomes contain fewer CG dinucleotides than would be expected by chance, and this pattern is mimicked by many viruses; HIV-1 derivatives mutated to…”
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Identification of a receptor for an extinct virus
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2010)“…The resurrection of endogenous retroviruses from inactive molecular fossils has allowed the investigation of interactions between extinct pathogens and their…”
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SNIP1 Is a Candidate Modifier of the Transcriptional Activity of c-Myc on E Box-Dependent Target Genes
Published in Molecular cell (08-12-2006)“…Using a yeast two-hybrid screen, we found that SNIP1 (Smad nuclear-interacting protein 1) associates with c-Myc, a key regulator of cell proliferation and…”
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Accumulation of Deleterious Mutations in Small Abiotic Populations of RNA
Published in Genetics (Austin) (01-01-2007)“…The accumulation of slightly deleterious mutations in populations leads to the buildup of a genetic load and can cause the extinction of populations of small…”
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Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5alpha proteins
Published in PLoS pathogens (01-10-2008)“…Because of evolutionary pressures imposed through episodic colonization by retroviruses, many mammals express factors, such as TRIM5alpha and APOBEC3 proteins,…”
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Evidence for Restriction of Ancient Primate Gammaretroviruses by APOBEC3 but Not TRIM5α Proteins
Published in PLoS pathogens (17-10-2008)“…Because of evolutionary pressures imposed through episodic colonization by retroviruses, many mammals express factors, such as TRIM5α and APOBEC3 proteins,…”
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Assisted Evolution Enables HIV-1 to Overcome a High TRIM5[alpha]-Imposed Genetic Barrier to Rhesus Macaque Tropism: e1003667
Published in PLoS pathogens (01-09-2013)“…Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon…”
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Journal Article -
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Evidence for Restriction of Ancient Primate Gammaretroviruses by APOBEC3 but Not TRIM5[alpha] Proteins: e1000181
Published in PLoS pathogens (01-10-2008)“…Because of evolutionary pressures imposed through episodic colonization by retroviruses, many mammals express factors, such as TRIM5α and APOBEC3 proteins,…”
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Journal Article -
11
Assisted Evolution Enables HIV-1 to Overcome a High TRIM5 alpha -Imposed Genetic Barrier to Rhesus Macaque Tropism: e1003667
Published in PLoS pathogens (01-09-2013)“…Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon…”
Get full text
Journal Article