Search Results - "Solis, Norma V."

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  1. 1

    Control of β-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence by Yang, Mengli, Solis, Norma V, Marshall, Michaela, Garleb, Rachel, Zhou, Tingting, Wang, Daidong, Swidergall, Marc, Pearlman, Eric, Filler, Scott G, Liu, Haoping

    Published in PLoS pathogens (01-01-2022)
    “…Candida albicans is a major opportunistic pathogen of humans. It can grow as morphologically distinct yeast, pseudohyphae and hyphae, and the ability to switch…”
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  2. 2

    Mucosal IgA Prevents Commensal Candida albicans Dysbiosis in the Oral Cavity by Millet, Nicolas, Solis, Norma V, Swidergall, Marc

    Published in Frontiers in immunology (22-10-2020)
    “…The fungus colonizes the oral mucosal surface of 30-70% of healthy individuals. Due to local or systemic immunosuppression, this commensal fungus is able to…”
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  3. 3

    Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection by Swidergall, Marc, Khalaji, Mina, Solis, Norma V, Moyes, David L, Drummond, Rebecca A, Hube, Bernhard, Lionakis, Michail S, Murdoch, Craig, Filler, Scott G, Naglik, Julian R

    Published in The Journal of infectious diseases (01-11-2019)
    “…Candidalysin is a cytolytic peptide toxin secreted by Candida albicans hyphae and has significantly advanced our understanding of fungal pathogenesis…”
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  4. 4

    Activation and alliance of regulatory pathways in C. albicans during mammalian infection by Xu, Wenjie, Solis, Norma V, Ehrlich, Rachel L, Woolford, Carol A, Filler, Scott G, Mitchell, Aaron P

    Published in PLoS biology (01-02-2015)
    “…Gene expression dynamics have provided foundational insight into almost all biological processes. Here, we analyze expression of environmentally responsive…”
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  5. 5

    Candida albicans Oropharyngeal Infection Is an Exception to Iron-Based Nutritional Immunity by Solis, Norma V, Wakade, Rohan S, Filler, Scott G, Krysan, Damian J

    Published in mBio (25-04-2023)
    “…Candida albicans is a commensal of the human gastrointestinal tract and a common cause of human fungal disease, including mucosal infections, such as…”
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  6. 6

    IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis by Millet, Nicolas, Solis, Norma V., Aguilar, Diane, Lionakis, Michail S., Wheeler, Robert T., Jendzjowsky, Nicholas, Swidergall, Marc

    Published in Nature communications (22-09-2022)
    “…During infection the host relies on pattern-recognition receptors to sense invading fungal pathogens to launch immune defense mechanisms. While fungal…”
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  7. 7

    Functional Dichotomy for a Hyphal Repressor in Candida albicans by Mao, Yinhe, Solis, Norma V, Filler, Scott G, Mitchell, Aaron P

    Published in mBio (25-04-2023)
    “…Nrg1 is a repressor of hypha formation and hypha-associated gene expression in the fungal pathogen Candida albicans. It has been well studied in the genetic…”
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  8. 8

    EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection by Zhu, Weidong, Phan, Quynh T, Boontheung, Pinmanee, Solis, Norma V, Loo, Joseph A, Filler, Scott G

    “…The fungus Candida albicans is the major cause of oropharyngeal candidiasis (OPC). A key feature of this disease is fungal invasion of oral epithelial cells, a…”
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  9. 9

    Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality by Lagree, Katherine, Woolford, Carol A, Huang, Manning Y, May, Gemma, McManus, C Joel, Solis, Norma V, Filler, Scott G, Mitchell, Aaron P

    Published in PLoS genetics (21-01-2020)
    “…Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way…”
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  10. 10

    Hyphal Als proteins act as CR3 ligands to promote immune responses against Candida albicans by Zhou, Tingting, Solis, Norma V., Marshall, Michaela, Yao, Qing, Garleb, Rachel, Yang, Mengli, Pearlman, Eric, Filler, Scott G., Liu, Haoping

    Published in Nature communications (09-05-2024)
    “…Patients with decreased levels of CD18 (β2 integrins) suffer from life-threatening bacterial and fungal infections. CD11b, the α subunit of integrin CR3…”
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  11. 11

    EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection by Swidergall, Marc, Solis, Norma V, Wang, Zeping, Phan, Quynh T, Marshall, Michaela E, Lionakis, Michail S, Pearlman, Eric, Filler, Scott G

    Published in Cell reports (Cambridge) (09-07-2019)
    “…During oropharyngeal candidiasis (OPC), Candida albicans proliferates and invades the superficial oral epithelium. Ephrin type-A receptor 2 (EphA2) functions…”
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  12. 12

    Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors by Swidergall, Marc, Solis, Norma V, Millet, Nicolas, Huang, Manning Y, Lin, Jianfeng, Phan, Quynh T, Lazarus, Michael D, Wang, Zeping, Yeaman, Michael R, Mitchell, Aaron P, Filler, Scott G

    Published in PLoS pathogens (20-01-2021)
    “…During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral epithelial cells, which respond by producing proinflammatory mediators that…”
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  13. 13

    Host cell invasion and virulence mediated by Candida albicans Ssa1 by Sun, Jianing N, Solis, Norma V, Phan, Quynh T, Bajwa, Jashanjot S, Kashleva, Helena, Thompson, Angela, Liu, Yaoping, Dongari-Bagtzoglou, Anna, Edgerton, Mira, Filler, Scott G

    Published in PLoS pathogens (01-11-2010)
    “…Candida albicans Ssa1 and Ssa2 are members of the HSP70 family of heat shock proteins that are expressed on the cell surface and function as receptors for…”
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  14. 14

    Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype by Forche, Anja, Solis, Norma V, Swidergall, Marc, Thomas, Robert, Guyer, Alison, Beach, Annette, Cromie, Gareth A, Le, Giang T, Lowell, Emily, Pavelka, Norman, Berman, Judith, Dudley, Aimeé M, Selmecki, Anna, Filler, Scott G

    Published in PLoS genetics (15-05-2019)
    “…When the fungus Candida albicans proliferates in the oropharyngeal cavity during experimental oropharyngeal candidiasis (OPC), it undergoes large-scale genome…”
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  15. 15

    Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection by Phan, Quynh T, Solis, Norma V, Cravener, Max V, Swidergall, Marc, Lin, Jianfeng, Huang, Manning Y, Liu, Hong, Singh, Shakti, Ibrahim, Ashraf S, Mazzone, Massimiliano, Mitchell, Aaron P, Filler, Scott G

    Published in PLoS pathogens (23-08-2023)
    “…Fungal invasion of the oral epithelium is central to the pathogenesis of oropharyngeal candidiasis (OPC). Candida albicans invades the oral epithelium by…”
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  16. 16

    The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis by Solis, Norma V, Swidergall, Marc, Bruno, Vincent M, Gaffen, Sarah L, Filler, Scott G

    Published in mBio (21-03-2017)
    “…Oropharyngeal candidiasis (OPC), caused predominantly by , is a prevalent infection in patients with advanced AIDS, defects in Th17 immunity, and head and neck…”
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  17. 17

    Hgc1 Independence of Biofilm Hyphae in Candida albicans by Sharma, Anupam, Solis, Norma V, Huang, Manning Y, Lanni, Frederick, Filler, Scott G, Mitchell, Aaron P

    Published in mBio (25-04-2023)
    “…Biofilm and hypha formation are central to virulence of the fungal pathogen Candida albicans. The G1 cyclin gene is required for hypha formation under diverse…”
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  18. 18

    Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes by Zhou, Xin, Hilk, Audrey, Solis, Norma V, Pereira De Sa, Nivea, Hogan, Bode M, Bierbaum, Tessa A, Del Poeta, Maurizio, Filler, Scott G, Burrack, Laura S, Selmecki, Anna

    Published in PLoS pathogens (30-07-2024)
    “…Ergosterol is essential for fungal cell membrane integrity and growth, and numerous antifungal drugs target ergosterol. Inactivation or modification of…”
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  19. 19

    Role of Arf GTPases in fungal morphogenesis and virulence by Labbaoui, Hayet, Bogliolo, Stéphanie, Ghugtyal, Vikram, Solis, Norma V, Filler, Scott G, Arkowitz, Robert A, Bassilana, Martine

    Published in PLoS pathogens (01-02-2017)
    “…Virulence of the human fungal pathogen Candida albicans depends on the switch from budding to filamentous growth, which requires sustained membrane traffic and…”
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  20. 20

    Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes by Alkafeef, Selma S, Lane, Shelley, Yu, Clinton, Zhou, Tingting, Solis, Norma V, Filler, Scott G, Huang, Lan, Liu, Haoping

    Published in PLoS genetics (11-06-2020)
    “…Iron is an essential nutrient required as a cofactor for many biological processes. As a fungal commensal-pathogen of humans, Candida albicans encounters a…”
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