Search Results - "Solinsky, M.G"

Sub-nanomolar hMC1R agonists by end-capping of the melanocortin tetrapeptide His-D-Phe-Arg-Trp-NH2 by KOIKOV, L. N, EBETINO, F. H, SOLINSKY, M. G, CROSS-DOERSEN, D, KNITTEL, J. J

Get full text

Analogs of sub-nanomolar hMC1R agonist LK-184 [Ph(CH 2) 3CO-His- d-Phe-Arg-Trp-NH 2]. An additional binding site within the human melanocortin receptor 1? by Koikov, L.N, Ebetino, F.H, Solinsky, M.G, Cross-Doersen, D, Knittel, J.J

“…Of the 29 analogs of LK-184 ( 1) tested at the human MC1, MC3, and MC4 receptors (R), only LK-312 ( 3), partially mimicking the π-system of 1, had an EC 50 of…”
Get full text

Sub-Nanomolar hMC1R Agonists by End-Capping of the Melanocortin Tetrapeptide His- d-Phe-Arg-Trp-NH 2 by Koikov, L.N, Ebetino, F.H, Solinsky, M.G, Cross-Doersen, D, Knittel, J.J

“…Twenty three derivatives of the core fragment His 6- d-Phe 7-Arg 8-Trp 9-NH 2 end-capped with carboxylic and sulfonic acids were synthesized and evaluated at…”
Get full text