Search Results - "Soleymani, Sepehr"
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Significance of serum antibodies against HPV E7, Hsp27, Hsp20 and Hp91 in Iranian HPV-exposed women
Published in BMC infectious diseases (12-02-2019)“…Among different types of human papillomavirus (HPV), types 16 and 18 were known to be high-risk agents causing mainly cervical cancer. Up to now, the potential…”
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2
Enhanced gene delivery in tumor cells using chemical carriers and mechanical loadings
Published in PloS one (28-12-2018)“…Intracellular delivery of DNA is considered a challenge in biological research and treatment of diseases. The previously reported transfection rate by…”
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3
In Vitro Anti-Viral Effects of Small Heat Shock Proteins 20 and 27: A Novel Therapeutic Approach
Published in Current pharmaceutical biotechnology (01-01-2019)“…The protective effects of heat shock proteins (Hsps) were studied in some infectious and non-infectious diseases, but their specificity was slightly known in…”
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4
Combination of Mechanical and Chemical Methods Improves Gene Delivery in Cell-based HIV Vaccines
Published in Current drug delivery (01-01-2019)“…Novel vaccination approaches are required to control human immunodeficiency virus (HIV) infections. The membrane proximal external region (MPER) of Env gp41…”
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5
Prospects and progress of Listeria-based cancer vaccines
Published in Expert opinion on biological therapy (02-11-2017)“…The development of an effective therapeutic vaccine to induce cancer-specific immunity remains problematic. Recently, a species of intracellular pathogen known…”
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6
Platelet microparticles: An effective delivery system for anti-viral drugs
Published in Journal of drug delivery science and technology (01-06-2019)“…Platelet microparticles are the most frequent bloodstream microparticles (∼70–90%) which act as a vector for delivery of mRNA, miRNA and signaling proteins…”
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7
Piroxicam Analogs: Design, Synthesis, Docking Study and Biological Evaluation as Promising Anti-HIV-1 Agents
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-02-2022)“…In this study, we describe the synthesis, docking study and biological evaluation of 1,2-benzothiazines 1,1-dioxide derivatives. Taking the well-known drug,…”
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8
Small heat shock protein 27: An effective adjuvant for enhancement of HIV-1 Nef antigen-specific immunity
Published in Immunology letters (01-11-2017)“…•Nef protein is an attractive target in therapeutic HIV vaccine development.•The immunogenicity of antigens can be increased by molecular adjuvants.•Hsp27…”
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9
Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents
Published in Iranian journal of pharmaceutical research : IJPR (01-01-2021)“…A novel series of benzothiazine-3-carboxamide 1,1-dioxide derivatives by modifying the piroxicam scaffold was designed, synthesized, and evaluated as anti-HIV…”
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10
Delivery of molecular cargoes in normal and cancer cell lines using non-viral delivery systems
Published in Biotechnology letters (01-06-2018)“…Objective In this study, transfection efficiency of human papillomavirus (HPV) E7 DNA and protein constructs into HEK-293T normal cell line, and A549 and TC-1…”
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11
Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2 H -benzo[ e ][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents
Published in Iranian journal of pharmaceutical research : IJPR (2021)“…A novel series of benzothiazine-3-carboxamide 1,1-dioxide derivatives by modifying the piroxicam scaffold was designed, synthesized, and evaluated as anti-HIV…”
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12
In vitro effect of branched polyethyleneimine (bPEI) on cells infected with human immunodeficiency virus: enhancement of viral replication
Published in Archives of virology (01-12-2019)“…Polyethyleneimine (PEI) is a chemical compound that used is as a carrier in gene therapy/delivery. Some studies have investigated the microbicidal potential…”
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13
Synthesis of Novel 3-(5-(Alkyl/arylthio)-1,3,4-Oxadiazol-2-yl)-8-Phenylquinolin-4(1H)-One Derivatives as Anti-HIV Agents
Published in Phosphorus, sulfur, and silicon and the related elements (03-04-2018)“…Novel quinolone derivatives featuring an 1,3,4-oxadiazole ring as a metal-chelating component and a benzyl group base on HIV-1 integrase inhibitors…”
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14
Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 4‐[4‐Arylpyridin‐1(4H)‐yl]benzoic Acid Derivatives as Anti‐HIV‐1 Agents
Published in Chemistry & biodiversity (01-12-2017)“…The structural similarities between N1 substituted 1,4‐dihydropyridines and the known gp41 inhibitors, NB‐2 and NB‐64, were considered in the current research…”
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15
Inherent anti-HIV activity of biocompatible anionic citrate-PEG-citrate dendrimer
Published in Molecular biology reports (01-02-2019)“…The development of new combinations to empower better protection against HIV infection is particularly important. Anionic polymers can block HIV infection. In…”
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16
The structural HCV genes delivered by MPG cell penetrating peptide are directed to enhance immune responses in mice model
Published in Drug delivery (12-10-2016)“…One of the significant problems in vaccination projects is the lack of an effective vaccine against hepatitis C virus (HCV). The goal of the current study is…”
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17
Design, Synthesis, and Anti‐HIV‐1 Evaluation of a Novel Series of 1,2,3,4‐Tetrahydropyrimidine‐5‐Carboxylic Acid Derivatives
Published in Chemistry & biodiversity (01-04-2018)“…A series of tetrahydropyrimidine derivatives (2a – 2l) were designed, synthesized, and screened for anti‐HIV‐1 properties based on the structures of HIV‐1 gp41…”
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18
Design, Synthesis, Molecular Modeling, In Silico ADME Studies and Anti-HIV-1 Assay of New Diazocoumarin Derivatives
Published in Iranian journal of pharmaceutical research : IJPR (01-09-2018)“…Some new diazo incorporated coumarin compounds were designed and synthesized to evaluate their anti-HIV activity. Overall, compounds were active against HIV at…”
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19
Simultaneous formulation of influenza vaccine and chitosan nanoparticles within CpG oligodesoxi nucleotides leads to dose-sparing and protects against lethal challenge in the mouse model
Published in Pathogens and disease (01-11-2018)“…Abstract Lack of efficient delivery systems for transporting antigenic molecules to the cytosol of antigen-presenting cells presents a major obstacle for…”
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20
Low prevalence of hepatitis B vaccine escape mutants among individuals born after the initiation of a nationwide vaccination program in Iran
Published in Archives of virology (01-12-2016)“…A nationwide hepatitis B virus (HBV) vaccination program for neonates was launched in Iran in 1993. Despite the success of this program, concern about its…”
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