Search Results - "Solessio, Eduardo"
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Speed, Spatial, and Temporal Tuning of Rod and Cone Vision in Mouse
Published in The Journal of neuroscience (02-01-2008)“…Rods and cones subserve mouse vision over a 100 million-fold range of light intensity (-6 to 2 log cd m(-2)). Rod pathways tune vision to the temporal…”
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Rod Photoresponse Kinetics Limit Temporal Contrast Sensitivity in Mesopic Vision
Published in The Journal of neuroscience (17-04-2019)“…The mammalian visual system operates over an extended range of ambient light levels by switching between rod and cone photoreceptors. Rod-driven vision is…”
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Generation of functional eyes from pluripotent cells
Published in PLoS biology (18-08-2009)“…Pluripotent cells such as embryonic stem (ES) and induced pluripotent stem (iPS) cells are the starting point from which to generate organ specific cell types…”
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Ablation of the proapoptotic genes CHOP or Ask1 does not prevent or delay loss of visual function in a P23H transgenic mouse model of retinitis pigmentosa
Published in PloS one (11-02-2014)“…The P23H mutation in rhodopsin (Rho(P23H)) is a prevalent cause of autosomal dominant retinitis pigmentosa. We examined the role of the ER stress proteins,…”
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The relationship between slow photoresponse recovery rate and temporal resolution of vision
Published in The Journal of neuroscience (10-10-2012)“…The rate at which photoreceptors recover from excitation is thought to be critical for setting the temporal resolution of vision. Indeed, mutations in RGS9…”
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An inducible expression system to measure rhodopsin transport in transgenic Xenopus rod outer segments
Published in PloS one (06-12-2013)“…We developed an inducible transgene expression system in Xenopus rod photoreceptors. Using a transgene containing mCherry fused to the carboxyl terminus of…”
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Cone degeneration following rod ablation in a reversible model of retinal degeneration
Published in Investigative ophthalmology & visual science (01-01-2011)“…Amphibian retinas regenerate after injury, making them ideal for studying the mechanisms of retinal regeneration, but this leaves their value as models of…”
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Regulation of rhodopsin-eGFP distribution in transgenic xenopus rod outer segments by light
Published in PloS one (15-11-2013)“…The rod outer segment (OS), comprised of tightly stacked disk membranes packed with rhodopsin, is in a dynamic equilibrium governed by a diurnal rhythm with…”
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Rod Photoreceptors Signal Fast Changes in Daylight Levels Using a Cx36-Independent Retinal Pathway in Mouse
Published in The Journal of neuroscience (22-01-2020)“…Temporal contrast detected by rod photoreceptors is channeled into multiple retinal rod pathways that ultimately connect to cone photoreceptor pathways via…”
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Membrane properties of an unusual intrinsically oscillating, wide-field teleost retinal amacrine cell
Published in The Journal of physiology (01-11-2002)“…In the retina, amacrine cells modulate the transfer of information from bipolar to ganglion cells. The nature of the modulation depends on the synaptic input…”
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Loss of scotopic contrast sensitivity in the optomotor response of diabetic mice
Published in Investigative ophthalmology & visual science (28-02-2013)“…Diabetes reduces retinal and visual sensitivity to dim light flashes. However, the impact of diabetes on contrast sensitivity in dim light is unknown. Based on…”
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Signal Detection Theoretic Estimates of the Murine Absolute Visual Threshold Are Independent of Decision Bias
Published in eNeuro (01-10-2024)“…Decision bias influences estimates of the absolute visual threshold. However, most psychophysical estimates of the murine absolute visual threshold have not…”
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A system to measure the pupil response to steady lights in freely behaving mice
Published in Journal of neuroscience methods (01-11-2016)“…•We present a system to measure the pupillary response to steady lights of freely behaving mice.•Our method uses a low-cost, portable device that automatically…”
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Antagonistic chromatic mechanisms in photoreceptors of the parietal eye of lizards
Published in Nature (London) (29-07-1993)“…Photoreceptors are the first in the chain of neurons that process visual information. In lateral eyes of vertebrates, light hyperpolarizes rod and cone…”
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An unusual cGMP pathway underlying depolarizing light response of the vertebrate parietal-eye photoreceptor
Published in Nature neuroscience (01-09-1998)“…All cellular signaling pathways currently known to elevate cGMP involve the activation of a guanylyl cyclase to synthesize cGMP. Here we describe an exception…”
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Cone-Driven Retinal Responses Are Shaped by Rod But Not Cone HCN1
Published in The Journal of neuroscience (25-05-2022)“…Signal integration of converging neural circuits is poorly understood. One example is in the retina where the integration of rod and cone signaling is…”
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Differential impact of Kv8.2 loss on rod and cone signaling and degeneration
Published in Human molecular genetics (31-03-2022)“…Abstract Heteromeric Kv2.1/Kv8.2 channels are voltage-gated potassium channels localized to the photoreceptor inner segment. They carry IKx, which is largely…”
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Visual Temporal Contrast Sensitivity in the Behaving Mouse Shares Fundamental Properties with Human Psychophysics
Published in eNeuro (01-07-2018)“…The mammalian visual system has a remarkable capacity to detect differences in contrast across time, which is known as temporal contrast sensitivity (TCS)…”
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Temporal Contrast Sensitivity Increases despite Photoreceptor Degeneration in a Mouse Model of Retinitis Pigmentosa
Published in eNeuro (01-03-2021)“…The detection of temporal variations in amplitude of light intensity, or temporal contrast sensitivity (TCS), depends on the kinetics of rod photoresponse…”
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