Search Results - "Solesio, María E"

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    Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity by Solesio, María E., Peixoto, Pablo M., Debure, Ludovic, Madamba, Stephen M., de Leon, Mony J., Wisniewski, Thomas, Pavlov, Evgeny V., Fossati, Silvia

    Published in Aging cell (01-08-2018)
    “…Summary Mounting evidence suggests that mitochondrial dysfunction plays a causal role in the etiology and progression of Alzheimer's disease (AD). We recently…”
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    Journal Article
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    The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease by Solesio, María E, Prime, Tracy A, Logan, Angela, Murphy, Michael P, Del Mar Arroyo-Jimenez, María, Jordán, Joaquín, Galindo, María F

    Published in Biochimica et biophysica acta (01-01-2013)
    “…Parkinson's disease (PD) is a neurodegenerative disorder for which available treatments provide symptom relief but do not stop disease progression…”
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    Cannabidiol repairs behavioral and brain disturbances in a model of fetal alcohol spectrum disorder by Gasparyan, Ani, Navarro, Daniela, Navarrete, Francisco, Austrich-Olivares, Amaya, Scoma, Ernest R., Hambardikar, Vedangi D., Acosta, Gabriela B., Solesio, María E., Manzanares, Jorge

    Published in Pharmacological research (01-02-2023)
    “…Fetal alcohol spectrum disorder (FASD) includes neuropsychiatric disturbances related to gestational and lactational ethanol exposure. Available treatments are…”
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    Methadone induces CAD degradation and AIF-mediated necrotic-like cell death in neuroblastoma cells by Perez-Alvarez, Sergio, Iglesias-Guimarais, Victoria, Solesio, María E., Melero-Fernandez de Mera, Raquel María, Yuste, Víctor J., Galindo, María F., Jordán, Joaquín

    Published in Pharmacological research (01-04-2011)
    “…Methadone ( d, l-methadone hydrochloride) is a full-opioid agonist, originally developed as a substitution for heroin or other opiates abusers. Nowadays…”
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    ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore by Neginskaya, Maria A., Solesio, Maria E., Berezhnaya, Elena V., Amodeo, Giuseppe F., Mnatsakanyan, Nelli, Jonas, Elizabeth A., Pavlov, Evgeny V.

    Published in Cell reports (Cambridge) (02-01-2019)
    “…Permeability transition (PT) is an increase in mitochondrial inner membrane permeability that can lead to a disruption of mitochondrial function and cell…”
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    ATP Synthase and Mitochondrial Bioenergetics Dysfunction in Alzheimer's Disease by Patro, Somya, Ratna, Sujay, Yamamoto, Hianny A, Ebenezer, Andrew T, Ferguson, Dillon S, Kaur, Amanpreet, McIntyre, Brendan C, Snow, Ryan, Solesio, Maria E

    “…Alzheimer's Disease (AD) is the most common neurodegenerative disorder in our society, as the population ages, its incidence is expected to increase in the…”
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    The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain by Fossati, Silvia, Giannoni, Patrizia, Solesio, Maria E, Cocklin, Sarah L, Cabrera, Erwin, Ghiso, Jorge, Rostagno, Agueda

    Published in Neurobiology of disease (01-02-2016)
    “…Abstract Mitochondrial dysfunction has been recognized as an early event in Alzheimer's disease (AD) pathology, preceding and inducing neurodegeneration and…”
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    Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long‐Lived Growth Hormone Receptor Null Mice by Liu, Zhongbo, Solesio, Maria E, Schaffler, Mitchell B, Frikha‐Benayed, Dorra, Rosen, Clifford J, Werner, Haim, Kopchick, John J, Pavlov, Evgeny V, Abramov, Andrey Y, Yakar, Shoshana

    Published in Journal of bone and mineral research (01-01-2019)
    “…ABSTRACT Despite increased longevity and resistance to multiple stressors, growth hormone receptor null (GHRKO) mice exhibit severe skeletal impairment. The…”
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    Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics by Scoma, Ernest R., Da Costa, Renata T., Leung, Ho Hang, Urquiza, Pedro, Guitart-Mampel, Mariona, Hambardikar, Vedangi, Riggs, Lindsey M., Wong, Ching-On, Solesio, Maria E.

    “…Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that is present in all studied organisms. PolyP consists of…”
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    Inorganic polyphosphate (polyP) as an activator and structural component of the mitochondrial permeability transition pore by Solesio, Maria E, Elustondo, Pia A, Zakharian, Eleonora, Pavlov, Evgeny V

    Published in Biochemical Society transactions (15-02-2016)
    “…Mitochondrial permeability transition pore (mPTP) is a large channel located in the mitochondrial inner membrane. The opening of mPTP during pathological…”
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    The Glacier Ice Worm, Mesenchytraeus solifugus , Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress by Osorio, Teresa, Scoma, Ernest R, Shain, Daniel H, Melissaratos, Diana S, Riggs, Lindsey M, Hambardikar, Vedangi, Solesio, Maria E

    Published in Biology (Basel, Switzerland) (06-12-2022)
    “…The inorganic polymer, polyphosphate (polyP), is present in all organisms examined to date with putative functions ranging from the maintenance of…”
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    Impact of Aldosterone on the Failing Myocardium: Insights from Mitochondria and Adrenergic Receptors Signaling and Function by Guitart-Mampel, Mariona, Urquiza, Pedro, Borges, Jordana I., Lymperopoulos, Anastasios, Solesio, Maria E.

    Published in Cells (Basel, Switzerland) (19-06-2021)
    “…The mineralocorticoid aldosterone regulates electrolyte and blood volume homeostasis, but it also adversely modulates the structure and function of the…”
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