Search Results - "Soler, Laura"
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Ocular permeability, intraocular biodistribution of lipid nanocapsule formulation intended for retinal drug delivery
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2023)“…[Display omitted] Recently, cGMP analogues have been investigated for the treatment of inherited retinal degenerations (IRD) using intravitreal injections…”
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Topical noninvasive retinal drug delivery of a tyrosine kinase inhibitor: 3% cediranib maleate cyclodextrin nanoparticle eye drops in the rabbit eye
Published in Acta ophthalmologica (Oxford, England) (01-11-2022)“…Purpose Tyrosine kinase inhibitors inhibit VEGF receptors. If delivered to the retina, they might inhibit oedema and neovascularization such as in age‐related…”
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Virulence Factors in the Phytopathogen–Host Interactions: An Overview
Published in Journal of agricultural and food chemistry (22-07-2020)“…Phytopathogens are responsible for great losses in agriculture, once they are able to subvert or elude the host defense mechanisms through virulence factors…”
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Analysis of ochratoxin A, aflatoxin B1 and its biosynthetic precursors in cheese – Method development and market sample screening
Published in Food control (01-01-2023)“…The presence of Penicillium and Aspergillus fungi during cheese production may lead to the formation of ochratoxin A, aflatoxins, as well as their partly…”
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Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye drops: Ocular pharmacokinetics and pharmacologic effect on intraocular pressure
Published in Acta ophthalmologica (Oxford, England) (01-06-2021)“…Purpose Orally administered angiotensin II receptor blockers (ARBs) decrease intraocular pressure (IOP). Topical administration may reduce systemic side…”
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6
Mass spectrometry imaging as a potential technique for diagnostic of Huanglongbing disease using fast and simple sample preparation
Published in Scientific reports (10-08-2020)“…Huanglongbing (HLB) is a disease of worldwide incidence that affects orange trees, among other commercial varieties, implicating in great losses to the citrus…”
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Deoxynivalenol Induces Local Inflammation and Lesions in Tissues at Doses Recommended by the EU
Published in International journal of molecular sciences (10-09-2024)“…The mycotoxin deoxynivalenol (DON) is frequently present in cereals at low levels, resulting in its occurrence in food and feed. DON has been proven to alter…”
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Protein expression reveals a molecular sexual identity of avian primordial germ cells at pre-gonadal stages
Published in Scientific reports (28-09-2021)“…In poultry, in vitro propagated primordial germ cells (PGCs) represent an important tool for the cryopreservation of avian genetic resources. However, several…”
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Exposure to Zearalenone Leads to Metabolic Disruption and Changes in Circulating Adipokines Concentrations in Pigs
Published in Toxins (08-11-2021)“…Zearalenone (ZEN) is a mycotoxin classified as an endocrine disruptor. Many endocrine disruptors are also metabolic disruptors able to modulate energy balance…”
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Proteome changes induced by a short, non-cytotoxic exposure to the mycoestrogen zearalenone in the pig intestine
Published in Journal of proteomics (30-07-2020)“…Intestinal epithelial homeostasis is regulated by a complex network of signaling pathways. Among them is estrogen signaling, important for the proliferation…”
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Patients with Thyroid Dyshormonogenesis and DUOX2 Variants: Molecular and Clinical Description and Genotype-Phenotype Correlation
Published in International journal of molecular sciences (01-08-2024)“…Thyroid dyshormonogenesis (THD) is a heterogeneous group of genetic diseases caused by the total or partial defect in the synthesis or secretion of thyroid…”
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Embryonic protein undernutrition by albumen removal programs the hepatic amino acid and glucose metabolism during the perinatal period in an avian model
Published in PloS one (01-04-2014)“…Different animal models have been used to study the effects of prenatal protein undernutrition and the mechanisms by which these occur. In mammals, the…”
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Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination
Published in Frontiers in immunology (05-07-2022)“…Cancer patients (CPs) have been identified as particularly vulnerable to SARS-CoV-2 infection, and therefore are a priority group for receiving COVID-19…”
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Intestinal toxicity of the new type A trichothecenes, NX and 3ANX
Published in Chemosphere (Oxford) (01-02-2022)“…NX and its acetylated form 3ANX are two new type A trichothecenes produced by Fusarium graminearum whose toxicity is poorly documented. The aim of this study…”
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Acute Exposure to Zearalenone Disturbs Intestinal Homeostasis by Modulating the Wnt/β-Catenin Signaling Pathway
Published in Toxins (11-02-2020)“…The mycotoxin zearalenone (ZEN), which frequently contaminates cereal-based human food and animal feed, is known to have an estrogenic effect. The biological…”
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The phenotype of the gut region is more stably retained than developmental stage in piglet intestinal organoids
Published in Frontiers in cell and developmental biology (29-08-2022)“…Intestinal organoids are innovative in vitro tools to study the digestive epithelium. The objective of this study was to generate jejunum and colon organoids…”
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Mutagenicity and genotoxicity assessment of the emerging mycotoxin Versicolorin A, an Aflatoxin B1 precursor
Published in Environmental pollution (1987) (15-10-2023)“…Aflatoxin B1 (AFB1) is the most potent natural carcinogen among mycotoxins. Versicolorin A (VerA) is a precursor of AFB1 biosynthesis and is structurally…”
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Growth promotion in broilers by both oxytetracycline and Macleaya cordata extract is based on their anti-inflammatory properties
Published in British journal of nutrition (14-10-2014)“…The non-antibiotic anti-inflammatory theory of antimicrobial growth promoters (AGP) predicts that alternatives can be selected by simple in vitro tests. In…”
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Exposure of intestinal explants to NX, but not to DON, enriches the secretome in mitochondrial proteins
Published in Archives of toxicology (01-09-2022)“…NX is a type A trichothecene produced by Fusarium graminearum with limited information on its toxicity. NX is structurally similar to deoxynivalenol (DON),…”
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Proteomics and protein analyses of ovine and caprine body fluids: current studies and future promises
Published in Current protein & peptide science (01-02-2014)“…Our knowledge of the physiology and health of small ruminants, specifically sheep and goats, is frequently obtained by extrapolating information from other…”
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