Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behçet's Disease

Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behçet's Disease

Purpose: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings. Methods: Retrospective chart review of patients with Behçet's disease seen at the Far...

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Bibliographic Details
Published in:Seminars in ophthalmology Vol. 32; no. 6; pp. 764 - 771
Main Authors: Bazvand, Fatemeh, Zarei, Mohammad, Ebrahimiadib, Nazanin, Karkhaneh, Reza, Davoudi, Samaneh, Soleimanzadeh, Mahyar, Sharifian, Elaheh, Roohipoor, Ramak, Modjtahedi, Bobeck S.
Format: Journal Article
Language:English
Published: England Taylor & Francis 02-11-2017
Subjects:
Adult
Autoimmune disease
Behcet Syndrome - complications
Eye Diseases - etiology
Eye Diseases - physiopathology
Female
Fluorescein Angiography
Fundus Oculi
Humans
macular edema
Male
Middle Aged
Optic Nerve Diseases - physiopathology
papillitis
Retinal Vasculitis - physiopathology
Retrospective Studies
uveitis
Uveitis - physiopathology
vasculitis
Visual Acuity - physiology
Young Adult
Autoimmune disease
macular edema
uveitis
vasculitis
papillitis
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Summary:Purpose: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings. Methods: Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital. Results: Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity. Conclusion: The most common ocular findings in Behçet's disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis.
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ISSN:0882-0538
1744-5205
DOI:10.1080/08820538.2016.1178310