Search Results - "Solary, Eric"

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts by Paggetti, Jerome, Haderk, Franziska, Seiffert, Martina, Janji, Bassam, Distler, Ute, Ammerlaan, Wim, Kim, Yeoun Jin, Adam, Julien, Lichter, Peter, Solary, Eric, Berchem, Guy, Moussay, Etienne

“…Exosomes derived from solid tumor cells are involved in immune suppression, angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been…”
Get full text

Towards a classification of stem cells by Laplane, Lucie, Solary, Eric

“…The characteristic properties of stem cells - notably their ability to self-renew and to differentiate - have meant that they have traditionally been viewed as…”
Get full text

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia by Selimoglu-Buet, Dorothée, Wagner-Ballon, Orianne, Saada, Véronique, Bardet, Valérie, Itzykson, Raphaël, Bencheikh, Laura, Morabito, Margot, Met, Elisabeth, Debord, Camille, Benayoun, Emmanuel, Nloga, Anne-Marie, Fenaux, Pierre, Braun, Thorsten, Willekens, Christophe, Quesnel, Bruno, Adès, Lionel, Fontenay, Michaela, Rameau, Philippe, Droin, Nathalie, Koscielny, Serge, Solary, Eric

“…Chronic myelomonocytic leukemia (CMML) is a myelodysplastic syndrome/ myeloproliferative neoplasm whose diagnosis is currently based on the elevation of…”
Get full text

Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study of 1084 patients by Coltro, Giacomo, Mangaonkar, Abhishek A., Lasho, Terra L., Finke, Christy M., Pophali, Prateek, Carr, Ryan, Gangat, Naseema, Binder, Moritz, Pardanani, Animesh, Fernandez-Zapico, Martin, Robertson, Keith D., Bosi, Alberto, Droin, Nathalie, Vannucchi, Alessandro M., Tefferi, Ayalew, Hunter, Anthony, Padron, Eric, Solary, Eric, Patnaik, Mrinal M.

“…Loss-of-function TET2 mutations ( TET2 MT ) are frequent early clonal events in myeloid neoplasms and are thought to confer a fitness advantage to…”
Get full text

The role of host environment in cancer evolution by Solary, Eric, Lapane, Lucie

“…Somatic mutations in oncogene and tumor suppressor genes accumulate in healthy tissues throughout life and delineate clones with limited expansion…”
Get full text

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia by Lucas, Nolwenn, Duchmann, Matthieu, Rameau, Philippe, Noël, Floriane, Michea, Paula, Saada, Véronique, Kosmider, Olivier, Pierron, Gérard, Fernandez-Zapico, Martin E, Howard, Matthew T., King, Rebecca L., Niyongere, Sandrine, Diop, M’boyba Khadija, Fenaux, Pierre, Itzykson, Raphael, Willekens, Christophe, Ribrag, Vincent, Fontenay, Michaela, Padron, Eric, Soumelis, Vassili, Droin, Nathalie, Patnaik, Mrinal M, Solary, Eric

“…Islands of CD123 high cells have been commonly described in the bone marrow of patients with chronic myelomonocytic leukemia (CMML). Using a multiparameter…”
Get full text

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults by Savona, Michael R., Malcovati, Luca, Komrokji, Rami, Tiu, Ramon V., Mughal, Tariq I., Orazi, Attilio, Kiladjian, Jean-Jacques, Padron, Eric, Solary, Eric, Tibes, Raoul, Itzykson, Raphael, Cazzola, Mario, Mesa, Ruben, Maciejewski, Jaroslaw, Fenaux, Pierre, Garcia-Manero, Guillermo, Gerds, Aaron, Sanz, Guillermo, Niemeyer, Charlotte M., Cervantes, Francisco, Germing, Ulrich, Cross, Nicholas C.P., List, Alan F.

“…Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) are hematologically diverse stem cell malignancies sharing phenotypic features of both…”
Get full text

Acquired initiating mutations in early hematopoietic cells of CLL patients by Damm, Frederik, Mylonas, Elena, Cosson, Adrien, Yoshida, Kenichi, Della Valle, Véronique, Mouly, Enguerran, Diop, M'boyba, Scourzic, Laurianne, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Kikushige, Yoshikane, Davi, Frederick, Lambert, Jérôme, Gautheret, Daniel, Merle-Béral, Hélène, Sutton, Laurent, Dessen, Philippe, Solary, Eric, Akashi, Koichi, Vainchenker, William, Mercher, Thomas, Droin, Nathalie, Ogawa, Seishi, Nguyen-Khac, Florence, Bernard, Olivier A

“…Appropriate cancer care requires a thorough understanding of the natural history of the disease, including the cell of origin, the pattern of clonal evolution,…”
Get more information

Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia by Meldi, Kristen, Qin, Tingting, Buchi, Francesca, Droin, Nathalie, Sotzen, Jason, Micol, Jean-Baptiste, Selimoglu-Buet, Dorothée, Masala, Erico, Allione, Bernardino, Gioia, Daniela, Poloni, Antonella, Lunghi, Monia, Solary, Eric, Abdel-Wahab, Omar, Santini, Valeria, Figueroa, Maria E

“…Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in genes encoding epigenetic modifiers and aberrant DNA…”
Get full text

Whole exome sequencing for determination of tumor mutation load in liquid biopsy from advanced cancer patients by Koeppel, Florence, Blanchard, Steven, Jovelet, Cécile, Genin, Bérengère, Marcaillou, Charles, Martin, Emmanuel, Rouleau, Etienne, Solary, Eric, Soria, Jean-Charles, André, Fabrice, Lacroix, Ludovic

“…Tumor mutation load (TML) has been proposed as a biomarker of patient response to immunotherapy in several studies. TML is usually determined by tumor biopsy…”
Get full text

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS by Deplus, Rachel, Delatte, Benjamin, Schwinn, Marie K, Defrance, Matthieu, Méndez, Jacqui, Murphy, Nancy, Dawson, Mark A, Volkmar, Michael, Putmans, Pascale, Calonne, Emilie, Shih, Alan H, Levine, Ross L, Bernard, Olivier, Mercher, Thomas, Solary, Eric, Urh, Marjeta, Daniels, Danette L, Fuks, François

“…TET proteins convert 5‐methylcytosine to 5‐hydroxymethylcytosine, an emerging dynamic epigenetic state of DNA that can influence transcription. Evidence has…”
Get full text

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells by Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip R., Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence, Kroemer, Guido

“…The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to…”
Get full text

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia by Micol, Jean-Baptiste, Pastore, Alessandro, Inoue, Daichi, Duployez, Nicolas, Kim, Eunhee, Lee, Stanley Chun-Wei, Durham, Benjamin H., Chung, Young Rock, Cho, Hana, Zhang, Xiao Jing, Yoshimi, Akihide, Krivtsov, Andrei, Koche, Richard, Solary, Eric, Sinha, Amit, Preudhomme, Claude, Abdel-Wahab, Omar

“…Additional sex combs-like (ASXL) proteins are mammalian homologues of additional sex combs (Asx), a regulator of trithorax and polycomb function in Drosophila…”
Get full text

CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia by Allouch, Awatef, Voisin, Laurent, Zhang, Yanyan, Raza, Syed Qasim, Lecluse, Yann, Calvo, Julien, Selimoglu-Buet, Dorothée, de Botton, Stéphane, Louache, Fawzia, Pflumio, Françoise, Solary, Eric, Perfettini, Jean-Luc

“…Targeting the reprogramming and phagocytic capacities of tumor-associated macrophages (TAMs) has emerged as a therapeutic opportunity for cancer treatment…”
Get full text

Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia by ITZYKSON, Raphaël, KOSMIDER, Olivier, VEY, Norbert, BRAUN, Thorsten, HAFERLACH, Torsten, DREYFUS, François, CROSS, Nicholas C. P, PREUDHOMME, Claude, BERNARD, Olivier A, FONTENAY, Michaela, VAINCHENKER, William, SCHNITTGER, Susanne, RENNEVILLE, Aline, BIRNBAUM, Daniel, DROIN, Nathalie, SOLARY, Eric, GELSI-BOYER, Véronique, MEGGENDORFER, Manja, MORABITO, Margot, BERTHON, Céline, ADES, Lionel, FENAUX, Pierre, BEYNE-RAUZY, Odile

“…Several prognostic scoring systems have been proposed for chronic myelomonocytic leukemia (CMML), a disease in which some gene mutations-including ASXL1-have…”
Get full text

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML by Selimoglu-Buet, Dorothée, Badaoui, Bouchra, Benayoun, Emmanuel, Toma, Andréa, Fenaux, Pierre, Quesnel, Bruno, Etienne, Gabriel, Braun, Thorsten, Abermil, Nassera, Morabito, Margot, Droin, Nathalie, Solary, Eric, Wagner-Ballon, Orianne

Get full text

Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers by Danlos, François-Xavier, Grajeda-Iglesias, Claudia, Durand, Sylvère, Sauvat, Allan, Roumier, Mathilde, Cantin, Delphine, Colomba, Emeline, Rohmer, Julien, Pommeret, Fanny, Baciarello, Giulia, Willekens, Christophe, Vasse, Marc, Griscelli, Frank, Fahrner, Jean-Eudes, Goubet, Anne-Gaëlle, Dubuisson, Agathe, Derosa, Lisa, Nirmalathasan, Nitharsshini, Bredel, Delphine, Mouraud, Séverine, Pradon, Caroline, Stoclin, Annabelle, Rozenberg, Flore, Duchemin, Jérôme, Jourdi, Georges, Ellouze, Syrine, Levavasseur, Françoise, Albigès, Laurence, Soria, Jean-Charles, Barlesi, Fabrice, Solary, Eric, André, Fabrice, Pène, Frédéric, Ackerman, Félix, Mouthon, Luc, Zitvogel, Laurence, Marabelle, Aurélien, Michot, Jean-Marie, Fontenay, Michaela, Kroemer, Guido

“…The circulating metabolome provides a snapshot of the physiological state of the organism responding to pathogenic challenges. Here we report alterations in…”
Get full text

TET2 mutational status affects myelodysplastic syndrome evolution to chronic myelomonocytic leukemia by Quang, Violaine Tran, Podvin, Benjamin, Desterke, Christophe, Tarfi, Sihem, Barathon, Quentin, Badaoui, Bouchra, Freynet, Nicolas, Parinet, Vincent, Leclerc, Mathieu, Maury, Sébastien, Solary, Eric, Selimoglu-Buet, Dorothée, Duployez, Nicolas, Wagner-Ballon, Orianne, Sloma, Ivan

Get full text

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis by Quivoron, Cyril, Couronné, Lucile, Della Valle, Véronique, Lopez, Cécile K., Plo, Isabelle, Wagner-Ballon, Orianne, Do Cruzeiro, Marcio, Delhommeau, Francois, Arnulf, Bertrand, Stern, Marc-Henri, Godley, Lucy, Opolon, Paule, Tilly, Hervé, Solary, Eric, Duffourd, Yannis, Dessen, Philippe, Merle-Beral, Hélène, Nguyen-Khac, Florence, Fontenay, Michaëla, Vainchenker, William, Bastard, Christian, Mercher, Thomas, Bernard, Olivier A.

“…Loss-of-function mutations affecting one or both copies of the Ten-Eleven-translocation ( TET) 2 gene have been described in various human myeloid…”
Get full text

Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation by Bluteau, Dominique, Balduini, Alessandra, Balayn, Nathalie, Currao, Manuela, Nurden, Paquita, Deswarte, Caroline, Leverger, Guy, Noris, Patrizia, Perrotta, Silverio, Solary, Eric, Vainchenker, William, Debili, Najet, Favier, Remi, Raslova, Hana

“…Point mutations in the 5' UTR of ankyrin repeat domain 26 (ANKRD26) are associated with familial thrombocytopenia 2 (THC2) and a predisposition to leukemia…”
Get full text