Search Results - "Solanko, Lukasz M."

Membrane Orientation and Lateral Diffusion of BODIPY-Cholesterol as a Function of Probe Structure by Solanko, Lukasz M., Honigmann, Alf, Midtiby, Henrik Skov, Lund, Frederik W., Brewer, Jonathan R., Dekaris, Vjekoslav, Bittman, Robert, Eggeling, Christian, Wüstner, Daniel

“…Cholesterol tagged with the BODIPY fluorophore via the central difluoroboron moiety of the dye (B-Chol) is a promising probe for studying intracellular…”
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Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane by Solanko, Lukasz M., Sullivan, David P., Sere, Yves Y., Szomek, Maria, Lunding, Anita, Solanko, Katarzyna A., Pizovic, Azra, Stanchev, Lyubomir D., Pomorski, Thomas Günther, Menon, Anant K., Wüstner, Daniel

“…Transbilayer lipid asymmetry is a fundamental characteristic of the eukaryotic cell plasma membrane (PM). While PM phospholipid asymmetry is well documented,…”
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Photobleaching kinetics and time-integrated emission of fluorescent probes in cellular membranes by Wüstner, Daniel, Christensen, Tanja, Solanko, Lukasz M, Sage, Daniel

“…Since the pioneering work of Hirschfeld, it is known that time-integrated emission (TiEm) of a fluorophore is independent of fluorescence quantum yield and…”
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Quantitative fluorescence loss in photobleaching for analysis of protein transport and aggregation by Wüstner, Daniel, Solanko, Lukasz M, Lund, Frederik W, Sage, Daniel, Schroll, Hans J, Lomholt, Michael A

“…Fluorescence loss in photobleaching (FLIP) is a widely used imaging technique, which provides information about protein dynamics in various cellular regions…”
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The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase by Fog, Cathrine K., Zago, Paola, Malini, Erika, Solanko, Lukasz M., Peruzzo, Paolo, Bornaes, Claus, Magnoni, Raffaella, Mehmedbasic, Arnela, Petersen, Nikolaj H.T., Bembi, Bruno, Aerts, Johannes F.M.G., Dardis, Andrea, Kirkegaard, Thomas

“…Gaucher Disease is caused by mutations of the GBA gene which encodes the lysosomal enzyme acid beta-glucosidase (GCase). GBA mutations commonly affect GCase…”
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Fluorescent Sterols and Cholesteryl Esters as Probes for Intracellular Cholesterol Transport by Solanko, Katarzyna A., Modzel, Maciej, Solanko, Lukasz M., Wüstner, Daniel

“…Cholesterol transport between cellular organelles comprised vesicular trafficking and nonvesicular exchange; these processes are often studied by quantitative…”
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Embedding beyond electrostatics-The role of wave function confinement by Nåbo, Lina J, Olsen, Jógvan Magnus Haugaard, Holmgaard List, Nanna, Solanko, Lukasz M, Wüstner, Daniel, Kongsted, Jacob

“…We study excited states of cholesterol in solution and show that, in this specific case, solute wave-function confinement is the main effect of the solvent…”
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Dehydroergosterol as an Analogue for Cholesterol: Why It Mimics Cholesterol So Wellor Does It? by Pourmousa, Mohsen, Róg, Tomasz, Mikkeli, Risto, Vattulainen, llpo, Solanko, Lukasz M, Wüstner, Daniel, List, Nanna Holmgaard, Kongsted, Jacob, Karttunen, Mikko

“…Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most…”
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Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts by Berzina, Zane, Solanko, Lukasz M., Mehadi, Ahmed S., Jensen, Maria Louise V., Lund, Frederik W., Modzel, Maciej, Szomek, Maria, Solanko, Katarzyna A., Dupont, Alice, Nielsen, Gitte Krogh, Heegaard, Christian W., Ejsing, Christer S., Wüstner, Daniel

“…•Plasma-membrane derived sterol is transported to endo-lysosomes but becomes trapped in these organelles in NPC2 deficient cells.•A small sterol pool remains…”
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Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells by Lund, Frederik W, Lomholt, Michael A, Solanko, Lukasz M, Bittman, Robert, Wüstner, Daniel

“…Cholesterol is an important membrane component, but our knowledge about its transport in cells is sparse. Previous imaging studies using dehydroergosterol…”
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Fluorescent sterols and cholesteryl esters as probes for intracellular cholesterol transport: supplementary issue: Cellular anatomy of lipid traffic by Solanko, Katarzyna A, Modzel, Maciej, Solanko, Lukasz M, Wustner, Daniel

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The Second-Order Polarization Propagator Approximation (SOPPA) method coupled to the polarizable continuum model by Eriksen, Janus J., Solanko, Lukasz M., Nåbo, Lina J., Wüstner, Daniel, Sauer, Stephan P.A., Kongsted, Jacob

“…[Display omitted] •We combine SOPPA and PCM for excited state calculations in solution.•We address solvent effects on vertical excitation energies in…”
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The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidaseResearch in context by Cathrine K. Fog, Paola Zago, Erika Malini, Lukasz M. Solanko, Paolo Peruzzo, Claus Bornaes, Raffaella Magnoni, Arnela Mehmedbasic, Nikolaj H.T. Petersen, Bruno Bembi, Johannes F.M.G. Aerts, Andrea Dardis, Thomas Kirkegaard

“…Background: Gaucher Disease is caused by mutations of the GBA gene which encodes the lysosomal enzyme acid beta-glucosidase (GCase). GBA mutations commonly…”
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