Search Results - "Solá, Cristina Avendaño"
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CLINICAL RESEARCH AND DRUG REGULATION IN THE CHALLENGING TIMES OF INDIVIDUALIZED THERAPIES: A PIVOTAL ROLE OF CLINICAL PHARMACOLOGY
Published in Pharmacological research (01-01-2024)“…Since the 1980s, medical specialists in Clinical Pharmacology have been playing a crucial role in the development of drug regulation in Spain. In this article…”
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Gender inequity in the medical profession: the women doctors in Spain (WOMEDS) study
Published in Human resources for health (20-09-2023)“…The long-standing underrepresentation of women in leadership positions in medicine is well-known, but poorly documented globally. There is some evidence of the…”
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Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (16-09-2020)“…In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV and other viral pneumonia are associated with an…”
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Double-blind, randomized, controlled, trial to assess the efficacy of allogenic mesenchymal stromal cells in patients with acute respiratory distress syndrome due to COVID-19 (COVID-AT): A structured summary of a study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (06-01-2021)“…1. To assess the efficacy of Mesenchymal Stromal Cells (MSC) versus a control arm as described in the primary endpoint. 2. To evaluate the effects of MSC on…”
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Prevalence and Risk Factors of Prolonged Corrected QT Interval Among Children and Adolescents Treated With Antipsychotic Medications: A Long-Term Follow-Up in a Real-World Population
Published in Journal of clinical psychopharmacology (01-02-2017)“…This study aimed to describe the prevalence of corrected QT (QTc) interval disorders and the possible predisposing factors in children and adolescents treated…”
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A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study)
Published in Orphanet journal of rare diseases (20-08-2018)“…Minocycline is an old tetracycline antibiotic that has shown antiinflammatory and antiapoptotic properties in different neurological disease mouse models…”
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Bronchopulmonary Penetration of Isavuconazole in Pulmonary Transplant Recipients (PBISA01): Protocol for a Phase IV Clinical Trial With a Single Treatment Arm
Published in JMIR research protocols (01-09-2022)“…Aspergillosis is the most frequently observed invasive fungal disease (IFD) in lung transplant recipients. Isavuconazole (ISA) has shown a better safety…”
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Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (09-02-2021)“…IMPORTANCE: The optimal transfusion strategy in patients with acute myocardial infarction and anemia is unclear. OBJECTIVE: To determine whether a restrictive…”
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Patient involvement in clinical research: why, when, and how
Published in Patient preference and adherence (2016)“…The development of a patient-centered approach to medicine is gradually allowing more patients to be involved in their own medical decisions. However, this…”
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Feasibility and safety of treating non-unions in tibia, femur and humerus with autologous, expanded, bone marrow-derived mesenchymal stromal cells associated with biphasic calcium phosphate biomaterials in a multicentric, non-comparative trial
Published in Biomaterials (01-03-2019)“…ORTHO-1 is a European, multicentric, first in human clinical trial to prove safety and feasibility after surgical implantation of commercially available…”
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Bronchopulmonary penetration of isavuconazole in lung transplant recipients
Published in Antimicrobial agents and chemotherapy (18-10-2023)“…Isavuconazole’s (ISA) pharmacokinetics was studied among lung transplant recipients to evaluate its bronchopulmonary penetration. This study included 13…”
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The Right Time for Steroids in COVID-19
Published in Clinical infectious diseases (26-04-2021)Get full text
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Early efficacy evaluation of mesenchymal stromal cells (MSC) combined to biomaterials to treat long bone non-unions
Published in Injury (01-04-2020)“…•Bone healing efficacy was clinically observed in long bone non-union treated with MSC combined to bioceramics.•Clinical and radiological healing of tibia,…”
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Cervical Pessary Compared With Vaginal Progesterone for Preventing Early Preterm Birth: A Randomized Controlled Trial
Published in Obstetrics and gynecology (New York. 1953) (01-10-2018)“…OBJECTIVE:To compare the effectiveness of a cervical pessary and vaginal progesterone to prevent spontaneous preterm births in pregnant women with cervical…”
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Role of Hospital Exemption in Europe: position paper from the Spanish Advanced Therapy Network (TERAV)
Published in Bone marrow transplantation (Basingstoke) (01-06-2023)Get full text
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Longer intervals between SARS‐CoV‐2 infection and mRNA‐1273 doses improve the neutralization of different variants of concern
Published in Journal of medical virology (01-03-2023)“…The humoral immune response against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants of concern elicited by vaccination was evaluated in…”
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Factors related to the development of high antibody titres against SARS‐CoV‐2 in convalescent plasma donors from the ConPlas‐19 trial
Published in Vox sanguinis (01-01-2024)“…Background and Objectives The efficacy of COVID‐19 convalescent plasma (CP) associates with high titres of antibodies. ConPlas‐19 clinical trial showed that CP…”
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Pathogen reduction with methylene blue does not have an impact on the clinical effectiveness of COVID‐19 convalescent plasma
Published in Vox sanguinis (01-04-2023)“…Background and Objectives There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of…”
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Association of Convalescent Plasma Treatment With Clinical Status in Patients Hospitalized With COVID-19: A Meta-analysis
Published in JAMA network open (04-01-2022)“…COVID-19 convalescent plasma (CCP) is a potentially beneficial treatment for COVID-19 that requires rigorous testing. To compile individual patient data from…”
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Osteonecrosis of the Femoral Head Safely Healed with Autologous, Expanded, Bone Marrow-Derived Mesenchymal Stromal Cells in a Multicentric Trial with Minimum 5 Years Follow-Up
Published in Journal of clinical medicine (01-02-2021)“…: Osteonecrosis (ON) of the femoral head represents a potentially severe disease of the hip where the lack of bone regeneration may lead to femoral head…”
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