Higher serum triglyceride level in patients with acute ischemic stroke is associated with lower infarct volume on CT brain scans

We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47-93 years) with anterior circulation (75%), posterior cir...

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Bibliographic Details
Published in:	European neurology Vol. 55; no. 2; p. 89
Main Authors:	Pikija, Slaven, Milevcić, Drazen, Trkulja, Vladimir, Kidemet-Piskac, Spomenka, Pavlicek, Ivan, Sokol, Nedeljko
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-2006
Subjects:	Aged Aged, 80 and over Blood Glucose - metabolism Brain Infarction - blood Brain Infarction - diagnostic imaging Cholesterol - blood Female Humans Image Interpretation, Computer-Assisted Infarction, Anterior Cerebral Artery - blood Infarction, Anterior Cerebral Artery - diagnostic imaging Infarction, Posterior Cerebral Artery - blood Infarction, Posterior Cerebral Artery - diagnostic imaging Male Mathematical Computing Middle Aged Prognosis Risk Factors Tomography, X-Ray Computed Triglycerides - blood
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Summary:	We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47-93 years) with anterior circulation (75%), posterior circulation (9%) or lacunar infarcts (16%) were examined. All patients were admitted within 24 h of the symptom onset, and CT scans were taken over the subsequent 24-72 h. With adjustment for the infarct type, age, sex, timing of CT imaging (24-36, >36-48 or >48-72 h since admission), atrial fibrillation, hypertension, fasting cholesterol and glucose levels, a higher (> or =1.70 mmol/l) fasting serum triglyceride level (within 24 h after admission) was associated with a lower infarct volume (p = 0.014). In line with a recent report on milder clinical symptoms in acute ischemic stroke patients with higher triglycerides, the results suggest an independent association between serum triglyceride level and stroke severity.
ISSN:	0014-3022
DOI:	10.1159/000092780