Search Results - "Sohn, Youn Soo"
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Synthesis, characterization, and tumor selectivity of a polyphosphazene–platinum(II) conjugate
Published in Journal of controlled release (20-06-2005)“…A new amphiphilic poly(organophosphazene) was synthesized by stepwise nucleophilic substitutions with a hydrophilic methoxy poly(ethylene glycol) with an…”
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2
Synthesis, biodistribution and antitumor activity of hematoporphyrin–platinum(II) conjugates
Published in Bioorganic & medicinal chemistry (17-04-2003)“…A new series of platinum(II) complexes of pegylated hematoporphyrin derivatives with controlled hydrophobic/hydrophilic balance were synthesized by introducing…”
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3
A macromolecular prodrug of doxorubicin conjugated to a biodegradable cyclotriphosphazene bearing a tetrapeptide
Published in Bioorganic & medicinal chemistry letters (01-08-2005)“…A new biodegradable water-soluble phosphazene trimer–doxorubicin conjugate was synthesized and exhibited lower than free doxorubicin (IC 50 = 0.10 μM) but…”
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Secondary Structure Effect of Polypeptide on Reverse Thermal Gelation and Degradation of l/dl-Poly(alanine)–Poloxamer–l/dl-Poly(alanine) Copolymers
Published in Macromolecules (11-11-2008)“…Poly(alanine) end-capped poly(propylene glycol)−poly(ethylene glycol)−poly(propylene glycol) (PA−PLX−PA) aqueous solutions underwent sol-to-gel transition as…”
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Thermogelling Poly(ethylene oxide-b-propylene oxide-b-ethylene oxide) Disulfide Multiblock Copolymer as a Thiol-Sensitive Degradable Polymer
Published in Biomacromolecules (01-10-2006)“…We report a reverse thermogelling poly(ethylene oxide-b-propylene oxide-b-ethylene oxide) disulfide multiblock copolymer as a thiol-sensitive biodegradable…”
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6
Enzymatically degradable temperature-sensitive polypeptide as a new in-situ gelling biomaterial
Published in Journal of controlled release (01-07-2009)“…We are reporting a poly (ethylene glycol)- block-poly(alanine-co-phenyl alanine) (PEG-PAF) aqueous solution that undergoes sol-to-gel transition as the…”
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Thermogelling Poly(caprolactone-b-ethylene glycol-b-caprolactone) Aqueous Solutions
Published in Macromolecules (14-06-2005)“…Poly(caprolactone-b-ethylene glycol-b-caprolactone) (PCL−PEG−PCL) triblock copolymer aqueous solution (>15 wt %) undergoes the sol−gel−sol transition as the…”
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Thermogelling Aqueous Solutions of Alternating Multiblock Copolymers of Poly(l-lactic acid) and Poly(ethylene glycol)
Published in Biomacromolecules (01-06-2006)“…We are reporting alternating multiblock copolymers of poly(l-lactic acid)/poly(ethylene glycol) aqueous solution (>15 wt %) undergoing sol−gel−sol transition…”
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9
Stereoisomeric Effect on Reverse Thermal Gelation of Poly(ethylene glycol)/Poly(lactide) Multiblock Copolymer
Published in Macromolecules (10-07-2007)“…Aqueous solutions of both poly(ethylene glycol)/poly(dl-lactic acid) (PEG/PDLLA) and poly(ethylene glycol)/poly(l-lactic acid) (PEG/PLLA) multiblock copolymers…”
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Gelation Behavior of Poly(ethylene glycol) and Polycaprolactone Triblock and Multiblock Copolymer Aqueous Solutions
Published in Macromolecules (11-07-2006)“…We reported aqueous solutions of poly(caprolactone-b-ethylene glycol-b-caprolactone) (PCL−PEG−PCL) that underwent sol−gel−sol transition as the temperature…”
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11
Reverse Thermal Gelling PEG−PTMC Diblock Copolymer Aqueous Solution
Published in Macromolecules (24-07-2007)“…In the search for a new thermogelling biomaterial, we are reporting poly(ethylene glycol)−poly(trimethylene carbonate) (PEG−PTMC) diblock copolymers. The…”
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12
Temperature-Sensitive Poly(caprolactone-co-trimethylene carbonate)−Poly(ethylene glycol)−Poly(caprolactone-co-trimethylene carbonate) as in Situ Gel-Forming Biomaterial
Published in Macromolecules (09-09-2008)“…We are reporting a new thermogelling poly(caprolactone-co-trimethylene carbonate)−poly(ethylene glycol)−poly(caprolactone-co-trimethylene carbonate)…”
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13
A Thermosensitive Poly(organophosphazene) Gel
Published in Macromolecules (07-05-2002)“…Thermosensitive poly(organophosphazenes) bearing α-amino-ω-methoxy-PEG (AMPEG) and hydrophobic l-isoleucine ethyl ester (IleOEt) as side groups have been…”
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14
A novel micelle-encapsulated platinum(II) anticancer agent
Published in Journal of controlled release (01-10-2010)“…A hydrophobic and water-insoluble platinum(II) compound, cis-(cha) 2Pt(NO 3) 2 was encapsulated by macromolecular micelles self-assembled from an amphiphilic…”
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15
Injectable gel: Poly(ethylene glycol)–sebacic acid polyester
Published in Polymer (Guilford) (17-05-2006)“…In order to develop an injectable material for drug delivery that has both formulation advantages of a sol-to-gel transition system and minimal burst release…”
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16
Cellular uptake and cytotoxicity of octahedral rhenium cluster complexes
Published in Journal of inorganic biochemistry (01-11-2008)“…Cellular uptake behavior of a novel class of octahedral rhenium cluster compounds, hexahydroxo complexes K 4[{Re 6S 8}(OH) 6] · 8H 2O (1) and K 4[{Re 6Se…”
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Synthesis and antitumor activity of novel polyphosphazene-(diamine)platinum(II) conjugates
Published in International journal of pharmaceutics (16-07-1997)“…A novel class of water-soluble polyphosphazene-(diamine)platinum(II) conjugate drugs [N=P(S)Am·PtA 2)] n have been designed and synthesized by incorporating…”
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18
Liposome Formulations for Effective Administration of Lipophilic Malonatoplatinum(II) Complexes
Published in Cancer science (01-11-2002)“…For effective administration of lipophilic trans(±)‐l,2‐diaminocyclohexaneplatinum(II) complexes of malonate derivatives [(dach)PtL, L=allylmalonate (AM),…”
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Synthesis and hydrolytic properties of polyphosphazene/(diamine)platinum/saccharide conjugates
Published in Journal of controlled release (13-11-1998)“…An antitumor (diamine)platinum moiety was introduced to poly(organophosphazene) by using dicarboxylate spacers, glutamate or aspartate. A liver targeting…”
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20
Tripodal amphiphiles tunable for self-assembly to polymersomes
Published in Journal of controlled release (25-02-2010)“…Cyclotriphosphazenes grafted with equimolar amounts of a hydrophilic polyethylene glycol and a hydrophobic oligopeptide in cis-nongeminal way form a new class…”
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