Search Results - "Sohn, Chang Ho"

Multiscale 3D phenotyping of human cerebral organoids by Albanese, Alexandre, Swaney, Justin M., Yun, Dae Hee, Evans, Nicholas B., Antonucci, Jenna M., Velasco, Silvia, Sohn, Chang Ho, Arlotta, Paola, Gehrke, Lee, Chung, Kwanghun

“…Brain organoids grown from human pluripotent stem cells self-organize into cytoarchitectures resembling the developing human brain. These three-dimensional…”
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Protection of tissue physicochemical properties using polyfunctional crosslinkers by Park, Young-Gyun, Sohn, Chang Ho, Chen, Ritchie, McCue, Margaret, Yun, Dae Hee, Drummond, Gabrielle T, Ku, Taeyun, Evans, Nicholas B, Oak, Hayeon Caitlyn, Trieu, Wendy, Choi, Heejin, Jin, Xin, Lilascharoen, Varoth, Wang, Ji, Truttmann, Matthias C, Qi, Helena W, Ploegh, Hidde L, Golub, Todd R, Chen, Shih-Chi, Frosch, Matthew P, Kulik, Heather J, Lim, Byung Kook, Chung, Kwanghun

“…Controlled tissue fixation with polyepoxides protects protein fluorescence, antigenicity, nucleic acids and tissue architecture. Understanding complex…”
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Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing by Shah, Sheel, Lubeck, Eric, Schwarzkopf, Maayan, He, Ting-Fang, Greenbaum, Alon, Sohn, Chang Ho, Lignell, Antti, Choi, Harry M T, Gradinaru, Viviana, Pierce, Niles A, Cai, Long

“…Accurate and robust detection of mRNA molecules in thick tissue samples can reveal gene expression patterns in single cells within their native environment…”
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Combinatorial gene regulation by modulation of relative pulse timing by Lin, Yihan, Sohn, Chang Ho, Dalal, Chiraj K., Cai, Long, Elowitz, Michael B.

“…Studies of individual living cells have revealed that many transcription factors activate in dynamic, and often stochastic, pulses within the same cell…”
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Enhancement of Gene Editing and Base Editing with Therapeutic Ribonucleoproteins through In Vivo Delivery Based on Absorptive Silica Nanoconstruct by Kim, Seongchan, Jeong, You Kyeong, Cho, Chang Sik, Lee, SeokHoon, Sohn, Chang Ho, Kim, Jeong Hun, Jeong, Youngdo, Jo, Dong Hyun, Bae, Sangsu, Lee, Hyojin

“…Key to the widespread and secure application of genome editing tools is the safe and effective delivery of multiple components of ribonucleoproteins (RNPs)…”
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Biomimetic Reagents for the Selective Free Radical and Acid–Base Chemistry of Glycans: Application to Glycan Structure Determination by Mass Spectrometry by Gao, Jinshan, Thomas, Daniel A, Sohn, Chang Ho, Beauchamp, J. L

“…Nature excels at breaking down glycans into their components, typically via enzymatic acid–base catalysis to achieve selective cleavage of the glycosidic bond…”
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Oxcarbazepine in the Treatment of Bipolar Disorder: A Review by Pratoomsri, Wetid, Yatham, Lakshmi N, Bond, David J, Lam, Raymond W, Sohn, Chang-Ho

“…Objective: To review the data on the efficacy of oxcarbazepine (OXC) in bipolar disorder (BD) and to provide recommendations for clinicians on the use of this…”
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Spatial Transcriptomics: Technical Aspects of Recent Developments and Their Applications in Neuroscience and Cancer Research by Park, Han‐Eol, Jo, Song Hyun, Lee, Rosalind H., Macks, Christian P., Ku, Taeyun, Park, Jihwan, Lee, Chung Whan, Hur, Junho K., Sohn, Chang Ho

“…Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation of the spatial localization of transcripts and related analyses in…”
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Treatment of seasonal affective disorder: unipolar versus bipolar differences by Sohn, Chang-Ho, Lam, Raymond W

“…Evidence-based treatments for seasonal affective disorder (SAD) include light therapy and pharmacotherapy. We briefly review the diagnosis and treatment of…”
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Elasticizing tissues for reversible shape transformation and accelerated molecular labeling by Ku, Taeyun, Guan, Webster, Evans, Nicholas B., Sohn, Chang Ho, Albanese, Alexandre, Kim, Joon-Goon, Frosch, Matthew P., Chung, Kwanghun

“…We developed entangled link-augmented stretchable tissue-hydrogel (ELAST), a technology that transforms tissues into elastic hydrogels to enhance…”
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Oxcarbazepine add-on in the treatment of refractory bipolar disorder by Pratoomsri, Wetid, Yatham, Lakshmi N, Sohn, Chang-Ho, Solomons, Kevin, Lam, Raymond W

“…Objective:  To assess the effectiveness and safety of oxcarbazepine (OXC) in bipolar disorder (BD) and related conditions. Methods:  We reviewed medical…”
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Click Chemistry Facilitates Formation of Reporter Ions and Simplified Synthesis of Amine-Reactive Multiplexed Isobaric Tags for Protein Quantification by Sohn, Chang Ho, Lee, J. Eugene, Sweredoski, Michael J, Graham, Robert L.J, Smith, Geoffrey T, Hess, Sonja, Czerwieniec, Gregg, Loo, Joseph A, Deshaies, Raymond J, Beauchamp, J. L

“…We report the development of novel reagents for cell-level protein quantification, referred to as Caltech isobaric tags (CITs), which offer several advantages…”
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Designer Reagents for Mass Spectrometry-Based Proteomics: Clickable Cross-Linkers for Elucidation of Protein Structures and Interactions by Sohn, Chang Ho, Agnew, Heather D, Lee, J. Eugene, Sweredoski, Michael J, Graham, Robert L.J, Smith, Geoffrey T, Hess, Sonja, Czerwieniec, Gregg, Loo, Joseph A, Heath, James R, Deshaies, Raymond J, Beauchamp, J. L

“…We present novel homobifunctional amine-reactive clickable cross-linkers (CXLs) for investigation of three-dimensional protein structures and protein–protein…”
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Update on the Biology of Seasonal Affective Disorder by Sohn, Chang-Ho, Lam, Raymond W.

“…The etiology and pathophysiology of seasonal affective disorder (SAD) has been linked to the seasons and to light since its first conceptualization. Aspects of…”
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Development of a cause analysis system for a CPCS trip by using the rule-base deduction method by Park, Je-Yun, Koo, In-Soo, Sohn, Chang-Ho, Kim, Jung-Seon, Cho, Gi-Ho, Park, Hee-Seok

“…A Core Protection Calculator System (CPCS) was developed to initiate a Reactor Trip under the circumstance of certain transients by a Combustion Engineering…”
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Molecular Decrowding by Tissue Expansion Allows Precise Determination of the Spatial Distribution of Synaptic Proteins at a Nanometer Scale by exTEM by Kim, Kang-Hoon, Yoon, Jubeen, Macks, Christian P., Park, Han-Eol, Youn, Jihyun, Lee, Jung-uk, An, Minji, Park, Jongseong, Ko, Jaewon, Sohn, Chang Ho

“…To understand how the molecular machinery of synapses works, it is essential to determine an inventory of synaptic proteins at a subsynaptic resolution…”
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Bioorthogonal imaging probe for STING protein in live cell and fixed tissue by Lee, Hyelim, Park, Ju-Young, Yoon, Jubeen, Park, Wonjin, Kang, Miso, Lee, Jeehee, Park, Gyubin, Koh, Minseob, Kim, Hyejin, Sohn, Chang Ho, Lee, Sanghee, Kim, Eunha

“…Stimulator of interferon genes (STING) is an endoplasmic reticulum membrane protein that plays a vital role in innate immunity. In this study, we report a new…”
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Online monitoring method using Equipotential Switching Direct Current potential drop for piping wall loss by flow accelerated corrosion by Ryu, Kyung Ha, Lee, Tae Hyun, Kim, Ji Hak, Hwang, Il Soon, Lee, Na Young, Kim, Ji Hyun, Park, Jin Ho, Sohn, Chang Ho

“…The flow accelerated corrosion (FAC) phenomenon persistently impacts plant reliability and personnel safety. We have shown that Equipotential Switching Direct…”
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Screening method for piping wall loss by flow accelerated corrosion by Ryu, Kyung Ha, Hwang, Il Soon, Lee, Na Young, Oh, Young Jin, Kim, Ji Hyun, Park, Jin Ho, Sohn, Chang Ho

“…Flow accelerated corrosion (FAC) phenomenon has persisted its impact on plant reliability and personnel safety. Unless we change the operation condition…”
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Hydrogen Bonding Constrains Free Radical Reaction Dynamics at Serine and Threonine Residues in Peptides by Thomas, Daniel A, Sohn, Chang Ho, Gao, Jinshan, Beauchamp, J. L

“…Free radical-initiated peptide sequencing (FRIPS) mass spectrometry derives advantage from the introduction of highly selective low-energy dissociation…”
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