Search Results - "Sohm, Frédéric"
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Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases
Published in Cell reports (Cambridge) (08-03-2016)“…Genome editing has now been reported in many systems using TALEN and CRISPR-Cas9 nucleases. Precise mutations can be introduced during homology-directed repair…”
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Lack of the myotendinous junction marker col22a1 results in posture and locomotion disabilities in zebrafish
Published in Matrix biology (01-05-2022)“…•Collagen XXII is the unique extracellular matrix marker of the myotendinous junction.•CRISPR/Cas9-mediated col22a1 gene knockout in zebrafish results in loss…”
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3
Astyanax transgenesis and husbandry: how cavefish enters the laboratory
Published in Zebrafish (01-08-2014)“…Astyanax mexicanus, a teleost fish comprising both sighted river-dwelling and blind cave-dwelling morphs, is becoming increasingly used in the field of…”
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Dual topologies of myotomal collagen XV and Tenascin C act in concert to guide and shape developing motor axons
Published in Proceedings of the National Academy of Sciences - PNAS (26-03-2024)“…During development, motor axons are guided toward muscle target by various extrinsic cues including extracellular matrix (ECM) proteins whose identities and…”
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Dynamic and differential expression of the gonadal aromatase during the process of sexual differentiation in a novel transgenic cyp19a1a-eGFP zebrafish line
Published in General and comparative endocrinology (15-05-2018)“…•A novel cyp19a1a-eGFP transgenic zebrafish line was developed.•Spatio-temporal expression of cyp19a1a in gonads during development was…”
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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish
Published in PloS one (29-07-2015)“…Presently, human collagen VI-related diseases such as Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM) remain incurable, emphasizing the…”
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Eye morphogenesis in the blind Mexican cavefish
Published in Biology open (15-10-2021)“…The morphogenesis of the vertebrate eye consists of a complex choreography of cell movements, tightly coupled to axial regionalization and cell type…”
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Postembryonic Fish Brain Proliferation Zones Exhibit Neuroepithelial‐Type Gene Expression Profile
Published in Stem cells (Dayton, Ohio) (01-06-2017)“…In mammals, neuroepithelial cells play an essential role in embryonic neurogenesis, whereas glial stem cells are the principal source of neurons at…”
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The Proximal Promoter Region of the Zebrafish gsdf Gene Is Sufficient to Mimic the Spatio-Temporal Expression Pattern of the Endogenous Gene in Sertoli and Granulosa Cells
Published in Biology of reproduction (01-12-2011)“…The gonadal soma-derived factor (GSDF) is a new member of the transforming growth factor beta (TGF-beta) superfamily that regulates the proliferation of the…”
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10
TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells
Published in Science advances (01-11-2019)“…Plasmacytoid dendritic cells (pDCs) play a crucial role in antiviral innate immunity through their unique capacity to produce large amounts of type I…”
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RESAMA: A Network for Monitoring Health and Husbandry Practices in Aquatic Research Facilities
Published in Zebrafish (01-07-2016)“…Health monitoring is a crucial aspect of the management of any research animal house. RESAMA is a network strong of 60 academic and private partners acting in…”
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Zebrafish: Housing and husbandry recommendations
Published in Laboratory animals (London) (01-06-2020)“…This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as part of the further implementation of Annex A to the European…”
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13
The Proximal Promoter Region of the Zebrafish gsdf Gene Is Sufficient to Mimic the Spatio-Temporal Expression Pattern of the Endogenous Gene in Sertoli and Granulosa Cells1
Published in Biology of reproduction (01-12-2011)“…The gonadal soma-derived factor (GSDF) is a new member of the transforming growth factor beta (TGF-beta) superfamily that regulates the proliferation of the…”
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14
Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation During Zebrafish Skull Vault Development
Published in Journal of bone and mineral research (01-09-2020)“…ABSTRACT Gain or loss‐of‐function mutations in fibroblast growth factor receptor 3 (FGFR3) result in cranial vault defects highlighting the protein's role in…”
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A mechano- and heat-gated two-pore domain K + channel controls excitability in adult zebrafish skeletal muscle
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2023)“…TRAAK channels are mechano-gated two-pore-domain K channels. Up to now, activity of these channels has been reported in neurons but not in skeletal muscle, yet…”
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16
Expression Cloning of a cDNA Encoding a Fish Prolactin Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-1995)“…By using an expression cloning strategy, we isolated a single positive clone encoding a tilapia prolactin (PRL) receptor. Tilapia PRL188was used to screen a…”
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Dual topologies of myotomal collagen XV and Tenascin C act in concert to guide and shape developing motor axons
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2024)“…During development, motor axons are guided toward muscle target by various extrinsic cues including extracellular matrix (ECM) proteins whose identities and…”
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18
The retinoblastoma susceptibility gene product/Sp1 signalling pathway is modulated by Ca2+/calmodulin kinases II and IV activity
Published in Oncogene (29-04-1999)“…To investigate the possible link between Ca2+ signalling and cell cycle control we analysed Ca2+/calmodulin kinases (CamK) interaction with the retinoblastoma…”
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Identification and Modulation of a Growth Hormone-Binding Protein in Rainbow Trout (Oncorhynchus mykiss) Plasma during Seawater Adaptation
Published in General and comparative endocrinology (01-08-1998)“…A soluble protein that specifically bound125I-human growth hormone (hGH) was identified in rainbow trout plasma, using HPLC-gel filtration. The binding…”
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Simultaneous overexpression of GH and STAT5b genes inhibits the STAT5 signalling pathway in tilapia (Oreochromis niloticus) embryos
Published in Genetics and molecular biology (2002)“…In this study, we describe the use of a STAT5 responsive element (LHRE) reporter gene to monitor the activity of the growth hormone (GH) transduction pathway…”
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