Search Results - "Sogutlu, Fatma"

MicroRNAs as Targets for Cancer Diagnosis: Interests and Limitations by Shademan, Behrouz, Karamad, Vahidreza, Nourazarian, Alireza, Masjedi, Sepideh, Isazadeh, Alireza, Sogutlu, Fatma, Avcı, Cigir Biray

“…MicroRNAs are small RNAs with ability to attach to the large number of RNA that regulate gene expression on post-transcriptional level via inhibition or…”
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Effect of valproic acid on miRNAs affecting histone deacetylase in a model of anaplastic thyroid cancer by Gunel, Nur Selvi, Birden, Nihal, Kurt, Cansu Caliskan, Bagca, Bakiye Goker, Shademan, Behrouz, Sogutlu, Fatma, Ozates, Neslihan Pinar, Avci, Cigir Biray

“…Background Thyroid cancer is the most common malignant tumor of the endocrine system seen in the thyroid gland. More than 90% of thyroid cancers comprise…”
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Enhanced Anti-cancer Potency Using a Combination of Oleanolic Acid and Maslinic Acid to Control Treatment Resistance in Breast Cancer by Avcı, Cigir Biray, Sogutlu, Fatma, Pinar Ozates, Neslihan, Shademan, Behrouz, Gunduz, Cumhur

“…Purpose: The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/ mTOR) pathway is a complex intracellular metabolic pathway that leads…”
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MicroRNAs as a New Target for Alzheimer's Disease Treatment by Shademan, Behrouz, Avci, Cigir Biray, Karamad, Vahidreza, Sogutlu, Fatma, Nourazarian, Alireza

“…Alzheimer's disease (AD) is the most common progressive neurodegenerative disease associated with advanced age. It is characterized by cognitive decline and…”
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The Evaluation of Effect of Aurora Kinase Inhibitor CCT137690 in Melanoma and Melanoma Cancer Stem Cell by Sogutlu, Fatma, Kayabasi, Cagla, Yelken, Besra O, Asik, Aycan, Gasimli, Roya, Kipcak, Sezgi, Susluer, Sunde Y, Avci, Cigir B, Gunduz, Cumhur

“…Dysregulation of the cell cycle is one of the main causes of melanomagenesis. Genomewide studies showed that the expression of Aurora -A and -B significantly…”
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Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells by Kaymaz, Burcin Tezcanli, Nur Selvi Gunel, Sogutlu, Fatma, Neslihan Pinar Ozates Ay, Baran, Yusuf, Gunduz, Cumhur, Avci, Cigir Biray

“…Objective(s): STATs are one of the initial targets of emerging anti-cancer agents due to their regulatory roles in survival, apoptosis, drug response, and…”
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Oxidative status in plasma, urine and saliva of girls with anorexia nervosa and healthy controls: a cross-sectional study by Kovalčíková, Alexandra Gaál, Tichá, Ľubica, Šebeková, Katarína, Celec, Peter, Čagalová, Alžbeta, Sogutlu, Fatma, Podracká, Ľudmila

“…Anorexia nervosa (AN) is a serious psychosomatic disorder with unclear pathomechanisms. Metabolic dysregulation is associated with disruption of redox…”
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Effects of rapamycin and AZD3463 combination on apoptosis, autophagy, and cell cycle for resistance control in breast cancer by Ozates, Neslihan Pınar, Soğutlu, Fatma, Lermioglu Erciyas, Ferzan, Demir, Busra, Gunduz, Cumhur, Shademan, Behrouz, Avci, Cigir Biray

“…Breast cancer is the most common cancer in women and the leading cause of cancer mortality in women over 40 it's the year. The existence of the PI3K/AKT/mTOR…”
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Investigation of the effect of telomerase inhibitor BIBR1532 on breast cancer and breast cancer stem cells by Doğan, Fatma, Özateş, Neslihan Pınar, Bağca, Bakiye Göker, Abbaszadeh, Zeka, Söğütlü, Fatma, Gasımlı, Röya, Gündüz, Cumhur, Biray Avcı, Çığır

“…It is emphasized that cancer stem cells (CSCs) forming the subpopulation of tumour cells are responsible for tumour growth, metastasis, and cancer drug…”
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Epigenetic signatures in gastric cancer: current knowledge and future perspectives by Sogutlu, Fatma, Pekerbas, Mert, Biray Avci, Cigir

“…Gastric cancer (GC) is the fifth most common malignancy in the world and accounts for 7.7% of all cancer-related deaths. Early diagnosis of GC is critical in…”
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Evaluation of the anticancer effect of telomerase inhibitor BIBR1532 in anaplastic thyroid cancer in terms of apoptosis, migration and cell cycle by Turkmen, Ecem, Sogutlu, Fatma, Erdogan, Mehmet, Biray Avci, Cigir

“…Anaplastic thyroid cancer (ATC) represents the type with the worst prognosis among thyroid cancers. In ATC with a highly invasive phenotype, selective…”
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Chk1/2 inhibitor AZD7762 enhances the susceptibility of IDH-mutant brain cancer cells to temozolomide by Ozgiray, Erkin, Sogutlu, Fatma, Biray Avci, Cigir

“…The IDH mutation initially exhibits chemosensitive properties, progression-free survival cannot be achieved in the later grades, and malignant transformation…”
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Photodynamic therapy potential of cobalt phthalocyanine in triple-negative breast cancer by Doğan, Şifa, Ince, Mine, Sogutlu, Fatma, Avci, Cigir Biray, Özel, Derya, Yurt, Fatma

“…Photodynamic therapy (PDT) is a safe treatment method for target-specific applications. In this study, the efficacy of PDT on triple-negative breast cancer…”
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CRISPR Technology in Cancer Diagnosis and Treatment: Opportunities and Challenges by Shademan, Behrouz, Masjedi, Sepideh, Karamad, Vahidreza, Isazadeh, Alireza, Sogutlu, Fatma, rad, Mohammad hosein saeedi, Nourazarian, Alireza

“…A novel gene editing tool, the Cas system, associated with the CRISPR system, is emerging as a potential method for genome modification. This simple method,…”
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PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia by Kayabasi, Cagla, Yelken, Besra Ozmen, Asik, Aycan, Okcanoglu, Tugce Balci, Sogutlu, Fatma, Gasimli, Roya, Susluer, Sunde Yilmaz, Saydam, Guray, Avci, Cigir Biray, Gunduz, Cumhur

“…Ponatinib is used for advanced treatment of chronic myeloid leukemia (CML), although low doses to prevent side effects do not suppress survival pathways and…”
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Relationship between miRNA-21, miRNA-155, and miRNA-182 expression and inflammatory factors in cerebrospinal fluid from patients with multiple sclerosis by Shademan, Behrouz, Zakeri, Mana, Abbasi, Samane, Biray Avci, Cigir, Karamad, Vahidreza, Sogutlu, Fatma, Laghousi, Delara, Nouri, Mohammad, Hassanpour, Mehdi, Nourazarian, Alireza

“…The impact of microRNAs (miRNAs) on the differentiation and function of inflammatory cells is well-established. MiRNAs play a crucial role in modulating the…”
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The effects of PKI-402 on breast tumor models' radiosensitivity via dual inhibition of PI3K/mTOR by Gasimli, Roya, Kayabasi, Cagla, Ozmen Yelken, Besra, Asik, Aycan, Sogutlu, Fatma, Celebi, Caglar, Yilmaz Susluer, Sunde, Kamer, Serra, Biray Avci, Cigir, Haydaroglu, Ayfer, Gunduz, Cumhur

“…PI3K/Akt/mTOR pathway activation causes relapse and resistance after radiotherapy in breast cancer (BC). We aimed to radiosensitize BC cell lines to…”
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Investigation of cytotoxic and apoptotic effects of disodium pentaborate decahydrate on ovarian cancer cells and assessment of gene profiling by Gunel, Nur Selvi, Yildirim, Nuri, Ozates, Neslihan Pinar, Oktay, Latife Merve, Bagca, Bakiye Goker, Sogutlu, Fatma, Ozsaran, Aydin, Korkmaz, Mehmet, Biray Avci, Cigir

“…After revealing the anti-cancer properties of boron, which is included in the category of essential elements for human health by the World Health Organization,…”
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The effect of ICRT‐3 on Wnt signaling pathway in head and neck cancer by Sogutlu, Fatma, Kayabasi, Cagla, Ozmen Yelken, Besra, Asik, Aycan, Gasimli, Roya, Dogan, Fatma, Yilmaz Süslüer, Sunde, Biray Avcı, Cigir, Gunduz, Cumhur

“…The effect of Wnt pathway in head and neck cancer could not be elucidated, even though the aberrant Wnt signaling plays a key role in the development of many…”
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Investigation of iso-propylchaetominine anticancer activity on apoptosis, cell cycle and Wnt signaling pathway in different cancer models by Karamad, Vahidreza, Sogutlu, Fatma, Ozkaya, Ferhat Can, Shademan, Behrouz, Ebrahim, Weaam, El-Neketi, Mona, Avci, Cigir Biray

“…Dysregulation of the Wnt signaling pathway contributes to the development of many cancer types. Natural compounds produced with biotechnological systems have…”
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