Search Results - "Sofia K. Forslund"
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eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses
Published in Nucleic acids research (08-01-2019)“…Abstract eggNOG is a public database of orthology relationships, gene evolutionary histories and functional annotations. Here, we present version 5.0,…”
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Gut Microbiome Composition in Obese and Non-Obese Persons: A Systematic Review and Meta-Analysis
Published in Nutrients (21-12-2021)“…Whether the gut microbiome in obesity is characterized by lower diversity and altered composition at the phylum or genus level may be more accurately…”
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Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage
Published in Circulation (New York, N.Y.) (12-03-2019)“…BACKGROUND:Arterial hypertension and its organ sequelae show characteristics of T cell–mediated inflammatory diseases. Experimental anti-inflammatory therapies…”
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Structure and function of the global topsoil microbiome
Published in Nature (London) (01-08-2018)“…Soils harbour some of the most diverse microbiomes on Earth and are essential for both nutrient cycling and carbon storage. To understand soil functioning, it…”
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Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients
Published in Nature communications (30-03-2021)“…Periods of fasting and refeeding may reduce cardiometabolic risk elevated by Western diet. Here we show in the substudy of NCT02099968, investigating the…”
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Similarity of the dog and human gut microbiomes in gene content and response to diet
Published in Microbiome (19-04-2018)“…Gut microbes influence their hosts in many ways, in particular by modulating the impact of diet. These effects have been studied most extensively in humans and…”
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Recovery of gut microbiota of healthy adults following antibiotic exposure
Published in Nature microbiology (01-11-2018)“…To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics resistance genes, collectively called their resistome. Using shotgun…”
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S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2020)“…After birth, the immune system matures via interactions with microbes in the gut. The S100 calcium binding proteins S100A8 and S100A9, and their extracellular…”
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The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)
Published in Frontiers in immunology (03-01-2022)“…Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected, debilitating multi-systemic disease without diagnostic marker or therapy…”
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The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials
Published in Cardiovascular research (02-05-2023)“…Abstract Although the available evidence emphasizes the beneficial effects of probiotics in normalizing various cardiometabolic markers, there is still…”
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Advances and Applications in the Quest for Orthologs
Published in Molecular biology and evolution (01-10-2019)“…Abstract Gene families evolve by the processes of speciation (creating orthologs), gene duplication (paralogs), and horizontal gene transfer (xenologs), in…”
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Towards monitoring of antimicrobial resistance in the environment: For what reasons, how to implement it, and what are the data needs?
Published in Environment international (01-08-2023)“…[Display omitted] •Background levels of environmental antimicrobial resistance need to be established.•How different AMR monitoring methods compare to each…”
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The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
Published in Nature communications (01-09-2023)“…Dietary lipids can affect metabolic health through gut microbiota-mediated mechanisms, but the influence of lipid-microbiota interaction on liver steatosis is…”
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Inflammation in Children with CKD Linked to Gut Dysbiosis and Metabolite Imbalance
Published in Journal of the American Society of Nephrology (01-12-2022)“…CKD is characterized by a sustained proinflammatory response of the immune system, promoting hypertension and cardiovascular disease. The underlying mechanisms…”
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The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life
Published in Journal of translational medicine (28-04-2021)“…The intestinal barrier plays an important role in the defense against infections, and nutritional, endocrine, and immune functions. The gut microbiota playing…”
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Salt Transiently Inhibits Mitochondrial Energetics in Mononuclear Phagocytes
Published in Circulation (New York, N.Y.) (13-07-2021)“…Dietary high salt (HS) is a leading risk factor for mortality and morbidity. Serum sodium transiently increases postprandially but can also accumulate at sites…”
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Domainoid: domain-oriented orthology inference
Published in BMC bioinformatics (28-10-2019)“…Orthology inference is normally based on full-length protein sequences. However, most proteins contain independently folding and recurring regions, domains…”
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The gut microbiota in multiple sclerosis varies with disease activity
Published in Genome medicine (05-01-2023)“…Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal cord resulting in physical and cognitive impairment in young adults. It is…”
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Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension
Published in Acta Physiologica (01-11-2024)“…Aims Metformin has been attributed to cardiovascular protection even in the absence of diabetes. Recent observations suggest that metformin influences the gut…”
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Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease
Published in Frontiers in immunology (17-01-2023)“…Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global mortality, with three million deaths reported annually. This impact is…”
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