Noninvasive computerized assessment of left ventricular performance and systemic hemodynamics by study of aortic root pressure and flow estimates in healthy men, and men with acute and healed myocardial infarction

Aortic root pressure and flow data can be used to assess left ventricular (LV) performance and properties of the systemic arterial tree. The calibrated subclavian arterial pulse trace was combined with echocardiographic imaging and Doppler velocity recordings to obtain noninvasive estimates of aorti...

Full description

Saved in:

Bibliographic Details
Published in:	The American journal of cardiology Vol. 72; no. 3; pp. 260 - 267
Main Authors:	Aakhus, Svend, Soerlie, Carsten, Faanes, Audun, Hauger, Svein O., Bjoernstad, Knut, Hatloe, Liv, Angelsen, Bjoern A.J.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-08-1993 Elsevier Limited
Subjects:	Adult Aged Aorta - diagnostic imaging Aorta - physiopathology Circulatory system Diagnosis, Computer-Assisted - instrumentation Diagnosis, Computer-Assisted - methods Diagnosis, Computer-Assisted - statistics & numerical data Echocardiography, Doppler - instrumentation Echocardiography, Doppler - methods Echocardiography, Doppler - statistics & numerical data Heart Hemodynamics Humans Male Medical research Men Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - epidemiology Myocardial Infarction - physiopathology Observer Variation Reference Values Reproducibility of Results Ventricular Function, Left
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Aortic root pressure and flow data can be used to assess left ventricular (LV) performance and properties of the systemic arterial tree. The calibrated subclavian arterial pulse trace was combined with echocardiographic imaging and Doppler velocity recordings to obtain noninvasive estimates of aortic root pressure and flow in 8 healthy subjects (group A), 12 patients with recent myocardial infarction (group B), and 8 with healed myocardial infarction and a dilated left ventricle (group C). The pressure and flow data were transferred to a computer and processed in specially designed software, including a new procedure for estimation of 3-element Windkessel model parameters. There were no significant group differences for either aortic root pressure estimates or heart rate. In groups B and C, stroke and cardiac indexes were lower and total peripheral resistance higher than in group A. There were no group differences in the model estimates of total arterial compliance, whereas the characteristic impedance was greater in group C than in A, indicating a less compliant aorta in C. Both LV total and steady power were less in groups B and C than in A, whereas no group difference was found for percent oscillatory power. The reproducibility for recording was good for the aortic root pressure estimates, and lower for the derived parameters (stroke and cardiac indexes, Windkessel model parameters and LV power), whereas that for interpretation was generally good. This method provides a unique noninvasive access to important parameters of LV function and the systemic circulation.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0002-9149 1879-1913
DOI:	10.1016/0002-9149(93)90670-8