Search Results - "Soenen, Stefaan J.H"
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Addressing the problem of cationic lipid-mediated toxicity: The magnetoliposome model
Published in Biomaterials (01-08-2009)“…Abstract The high biocompatibility and versatile nature of liposomes made these particles keystone components in many hot-topic research areas. For…”
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The labeling of cationic iron oxide nanoparticle-resistant hepatocellular carcinoma cells using targeted magnetoliposomes
Published in Biomaterials (01-02-2011)“…Abstract The in vitro labeling of cultured cells with nanomaterials is a frequent practice but the efficiency, specificity and cytotoxicity of labeling…”
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Cytotoxic effects of iron oxide nanoparticles and implications for safety in cell labelling
Published in Biomaterials (01-01-2011)“…Abstract The in vitro labelling of cultured cells with iron oxide nanoparticles (NPs) is a frequent practice in biomedical research. To date, the potential…”
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The role of nanoparticle concentration-dependent induction of cellular stress in the internalization of non-toxic cationic magnetoliposomes
Published in Biomaterials (01-12-2009)“…Abstract Magnetoliposomes (MLs), built up of ultrasmall iron oxide cores each individually surrounded by a lipid bilayer, have emerged as highly biocompatible…”
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Stable Long-Term Intracellular Labelling with Fluorescently Tagged Cationic Magnetoliposomes
Published in Chembiochem : a European journal of chemical biology (26-01-2009)“…Iron oxide nanocrystals that are dextran coated are widely exploited biomedically for magnetic resonance imaging (MRI), hyperthermia cancer treatment and drug…”
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Surface functionalization of magnetoliposomes in view of improving iron oxide-based magnetic resonance imaging contrast agents: Anchoring of gadolinium ions to a lipophilic chelate
Published in Analytical biochemistry (15-08-2007)“…Small unilamellar phospholipid vesicles containing the phosphatidylethanolamine–diethylene triamine pentaacetic acid (PE–DTPA) conjugate as one of the building…”
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Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge
Published in ACS nano (23-04-2013)“…To study charge-dependent interactions of nanoparticles (NPs) with biological media and NP uptake by cells, colloidal gold nanoparticles were modified with…”
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Intracellular Nanoparticle Coating Stability Determines Nanoparticle Diagnostics Efficacy and Cell Functionality
Published in Small (Weinheim an der Bergstrasse, Germany) (04-10-2010)“…Iron oxide nanoparticles (NPs) are frequently employed in biomedical research as magnetic resonance (MR) contrast agents where high intracellular levels are…”
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Assessing iron oxide nanoparticle toxicity in vitro: current status and future prospects
Published in Nanomedicine (London, England) (01-10-2010)“…The in vitro labeling of stem or therapeutic cells with engineered nanoparticles with the aim of transplanting these cells into live animals and, for example,…”
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High Intracellular Iron Oxide Nanoparticle Concentrations Affect Cellular Cytoskeleton and Focal Adhesion Kinase-Mediated Signaling
Published in Small (Weinheim an der Bergstrasse, Germany) (09-04-2010)“…Iron oxide nanoparticle internalization exerts detrimental effects on cell physiology for a variety of particles, but little is known about the mechanism…”
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Colloidal Gold Nanoparticles Induce Changes in Cellular and Subcellular Morphology
Published in ACS nano (22-08-2017)“…Exposure of cells to colloidal nanoparticles (NPs) can have concentration-dependent harmful effects. Mostly, such effects are monitored with biochemical assays…”
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Assessing cytotoxicity of (iron oxide-based) nanoparticles: an overview of different methods exemplified with cationic magnetoliposomes
Published in Contrast media and molecular imaging (01-09-2009)“…Iron oxide nanoparticles are the most widely used T(2)/T(2)* contrast agents and for biomedical research purposes, one of the main applications is the in vitro…”
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Magnetoliposomes: versatile innovative nanocolloids for use in biotechnology and biomedicine
Published in Nanomedicine (London, England) (01-02-2009)“…The high biocompatibility and versatile nature of liposomes have made these particles keystone components in many hot-topic biomedical research areas…”
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14
Optimal Conditions for Labelling of 3T3 Fibroblasts with Magnetoliposomes without Affecting Cellular Viability
Published in Chembiochem : a European journal of chemical biology (23-11-2007)“…A comparative study that deals with the internalisation of different types of magnetoliposomes (MLs) by 3T3 fibroblasts revealed that cationic MLs proved to be…”
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How to assess cytotoxicity of (iron oxide-based) nanoparticles: a technical note using cationic magnetoliposomes
Published in Contrast media and molecular imaging (01-05-2011)“…The range of different types of nanoparticles and their biomedical applications is rapidly growing, creating a need to thoroughly examine the effects these…”
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Background migration of USPIO/MLs is a major drawback for in situ labeling of endogenous neural progenitor cells
Published in Contrast media and molecular imaging (01-01-2011)“…MR-labeling of endogenous neural progenitor cells (NPCs) to follow up cellular migration with in vivo magnetic resonance imaging (MRI) is a very promising tool…”
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Cationic magnetoliposomes
Published in Methods in molecular biology (Clifton, N.J.) (2010)“…Magnetoliposomes (MLs) consist of nanosized, magnetisable iron oxide cores (magnetite, Fe(3)O(4)) which are individually enveloped by a bilayer of phospholipid…”
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Synthesis, physicochemical characterization and MR relaxometry of aqueous ferrofluids
Published in Journal of nanoscience and nanotechnology (01-05-2008)“…The synthesis and characterization of ferrofluid based MR contrast agents, which offer R2* versatility beyond that of ferucarbotran, is described. Ferrofluids…”
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Complexation of gadolinium(III) ions on top of nanometre-sized magnetoliposomes
Published in International journal of environmental analytical chemistry (20-08-2007)“…The complex of diethylenetriaminepentaacetate (DTPA) with the paramagnetic gadolinium ion [Gd(III)] is a well-known blood pool contrast agent for magnetic…”
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