Search Results - "Soeller, W"

Spontaneous Diabetes Mellitus in Transgenic Mice Expressing Human Islet Amyloid Polypeptide by Janson, Juliette, Soeller, Walter C., Roche, Patrick C., Nelson, Robin T., Torchia, Anthony J., Kreutter, David K., Butler, Peter C.

“…The islet in non-insulin-dependent diabetes mellitus (NIDDM) is characterized by loss of β cells and large local deposits of amyloid derived from the 37-amino…”
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Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide by Soeller, W C, Janson, J, Hart, S E, Parker, J C, Carty, M D, Stevenson, R W, Kreutter, D K, Butler, P C

“…Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide. W C Soeller , J Janson , S E Hart , J C Parker , M D Carty…”
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Isolation of cDNAs encoding the Drosophila GAGA transcription factor by SOELLER, W. C, EUK OH, C, KORNBERG, T. B

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction by M Couce, L A Kane, T D O'Brien, J Charlesworth, W Soeller, J McNeish, D Kreutter, P Roche, P C Butler

“…Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction. M…”
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In vitro transcription of the Drosophila engrailed gene by SOELLER, W. C, POOLE, S. J, KORNBERG, T

“…An enzyme system that accurately initiates transcription of the engrailed gene has been prepared from Drosophila embryos. The system has been separated…”
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Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle by Marshall, B.A., Ren, J.M., Johnson, D.W., Gibbs, E.M., Lillquist, J.S., Soeller, W.C., Holloszy, J.O., Mueckler, M.

“…Transgenic mice were constructed that overexpress the human Glut1 glucose transporter in skeletal muscle. Transcription of the human Glut1 cDNA was driven by…”
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The invected gene of Drosophila: sequence analysis and expression studies reveal a close kinship to the engrailed gene by Coleman, K G, Poole, S J, Weir, M P, Soeller, W C, Kornberg, T

“…The invected and engrailed genes are juxtaposed in the Drosophila genome and are closely related in sequence and pattern of expression. The structure of the…”
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Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells by Carty, M D, Lillquist, J S, Peshavaria, M, Stein, R, Soeller, W C

“…Islet amyloid polypeptide is expressed almost exclusively in pancreatic beta- and delta-cells. Here we report that beta cell-specific expression of the human…”
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The transcription unit of the Drosophila engrailed locus: an unusually small portion of a 70,000 bp gene by Drees, B., Ali, Z., Soeller, W. C., Coleman, K. G., Poole, S. J., Kornberg, T.

“…Transcripts from the engrailed gene of Drosophila melanogaster have been characterized by Northern, S1 nuclease sensitivity, and primer extension analyses. The…”
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IAPP/amylin gene transcriptional control region: evidence for negative regulation by Mosselman, S., Höppener, J.W.M., de Wit, L., Soeller, W., Lips, C.J.M., Jansz, H.S.

“…Aberrant expression of the islet amyloid polypeptide (IAPP) gene might be involved in the pathogenesis of nun-insulin-dependent diabetes mellitus (NIDDM)…”
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Maximal limits of the Escherichia coli replication factor Y effector site sequences in pBR322 DNA by Marians, K J, Soeller, W, Zipursky, S L

“…pBR322 DNA contains two separate regions on opposite strands and close to the origin of replication which, when in single-stranded form, can act as effectors…”
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Mutational analysis of primosome assembly sites. I. Distinct classes of mutants in the pBR322 Escherichia coli factor Y DNA effector sequences by Abarzúa, P, Soeller, W, Marians, K J

“…The assembly of the primosome, a multienzyme complex responsible for priming of lagging-strand DNA synthesis in Escherichia coli, occurs on defined regions of…”
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Mutational analysis of primosome assembly sites. II. Role of secondary structure in the formation of active sites by Soeller, W, Abarzúa, P, Marians, K J

“…Based on their activity as effectors for the ATPase activity of Escherichia coli replication factor Y and as templates for primosome-directed DNA synthesis,…”
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Deletion Mutants Defining the Escherichia coli Replication Factor Y Effector Site Sequences in pBR322 DNA by Soeller, W. C., Marians, K. J.

“…The Escherichia coli DNA replication factor Y, along with other genetically undefined replication proteins, is involved in a dnaB-, dnaC-, and dnaG-dependent…”
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Macrophage variants in oxygen metabolism by Damiani, G, Kiyotaki, C, Soeller, W, Sasada, M, Peisach, J, Bloom, B R

“…Whereas phagocytic cells from normal individuals have the capacity to kill ingested bacteria and parasites, those from patients with several uncommon genetic…”
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Increased β-cell apoptosis prevents adaptive increase in β-cell mass in mouse model of type 2 diabetes: Evidence for role of islet amyloid formation rather than direct action of amyloid by BUTLER, Alexandra E, JANSON, Juliette, SOELLER, Walter C, BUTLER, Peter C

“…Nondiabetic obese humans adapt to insulin resistance by increasing beta-cell mass. In contrast, obese humans with type 2 diabetes have an approximately 60%…”
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Diabetes due to a progressive defect in β-cell mass in rats transgenic for human islet amyloid polypeptide (HIP rat): A new model for type 2 diabetes by BUTLER, Alexandra E, JANG, Jennifer, GURLO, Tatyana, CARTY, Maynard D, SOELLER, Walter C, BUTLER, Peter C

“…The islet in type 2 diabetes is characterized by a deficit in beta-cell mass, increased beta-cell apoptosis, and impaired insulin secretion. Also, islets in…”
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Structure-Activity Analysis of the Purine Binding Site of Human Liver Glycogen Phosphorylase by Ekstrom, Jennifer L, Pauly, Thomas A, Carty, Maynard D, Soeller, Walter C, Culp, Jeff, Danley, Dennis E, Hoover, Dennis J, Treadway, Judith L, Gibbs, E.Michael, Fletterick, Robert J, Day, Yasmina S.N, Myszka, David G, Rath, Virginia L

“…Human liver glycogen phosphorylase (HLGP) catalyzes the breakdown of glycogen to maintain serum glucose levels and is a therapeutic target for diabetes. HLGP…”
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The engrailed locus of Drosophila melanogaster: genetic, developmental, and molecular studies by Ali, Z, Drees, B, Coleman, K G, Gustavson, E, Karr, T L, Kauvar, L M, Poole, S J, Soeller, W, Weir, M P, Kornberg, T

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Identification of a novel glucose transporter-like protein-GLUT-12 by Rogers, Suzanne, Macheda, Maria L, Docherty, Susan E, Carty, Maynard D, Henderson, Michael A, Soeller, Walter C, Gibbs, E Michael, James, David E, Best, James D

“…Facilitative glucose transporters exhibit variable hexose affinity and tissue-specific expression. These characteristics contribute to specialized metabolic…”
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