Search Results - "Soeiro‐de‐Souza, Marcio G."
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Treatment implications of predominant polarity and the polarity index: a comprehensive review
Published in The international journal of neuropsychopharmacology (01-01-2015)“…Bipolar disorder (BD) is a serious and recurring condition that affects approximately 2.4% of the global population. About half of BD sufferers have an illness…”
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Major depressive disorder in breast cancer: A critical systematic review of pharmacological and psychotherapeutic clinical trials
Published in Cancer treatment reviews (01-04-2014)“…Abstract Background While women with breast cancer often face varying levels of psychological distress, there is a subgroup whose symptomatology reaches a…”
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Affective temperaments and ego defense mechanisms associated with somatic symptom severity in a large sample
Published in Journal of affective disorders (05-09-2013)“…Abstract Background Several complex mechanisms including biological, psychological and social factors may contribute to the development of bodily symptoms…”
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Plasma cortisol in first episode drug-naïve mania: Differential levels in euphoric versus irritable mood
Published in Journal of affective disorders (01-04-2012)“…Abstract Background Dysregulation of HPA axis has been widely described in subjects with bipolar disorder (BD), including changes in cortisol levels during…”
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Multiple levels of impaired neural plasticity and cellular resilience in bipolar disorder: Developing treatments using an integrated translational approach
Published in The world journal of biological psychiatry (01-02-2014)“…Abstract Objectives. This paper reviews the neurobiology of bipolar disorder (BD), particularly findings associated with impaired cellular resilience and…”
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SIGMA-VB: Validity and reliability of the Brazilian Portuguese version of the Montgomery-Åsberg Depression Rating Scale using the Structured Interview Guide for the MADRS
Published in Revista brasileira de psiquiatria (01-07-2019)“…The Montgomery-Åsberg Depression Rating Scale (MADRS) is widely used to assess depression severity. The Structured Interview Guide for the MADRS (SIGMA) was…”
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Screening for bipolar depression in family medicine practices: Prevalence and clinical correlates
Published in Journal of affective disorders (01-06-2014)“…Abstract Background To compare individuals in primary care (PC) who screen positive for bipolar depression to those who screened positive for unipolar…”
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Role of quetiapine beyond its clinical efficacy in bipolar disorder: From neuroprotection to the treatment of psychiatric disorders (Review)
Published in Experimental and therapeutic medicine (01-03-2015)“…The aim of the present review was to discuss the following aspects of treatment with quetiapine in psychiatric disorders: i) Neurocognition and functional…”
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In vivo hippocampal subfield volumes in bipolar disorder—A mega‐analysis from The Enhancing Neuro Imaging Genetics through Meta‐Analysis Bipolar Disorder Working Group
Published in Human brain mapping (01-01-2022)“…The hippocampus consists of anatomically and functionally distinct subfields that may be differentially involved in the pathophysiology of bipolar disorder…”
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Lithium efficacy in bipolar depression with flexible dosing: A six-week, open-label, proof-of-concept study
Published in Experimental and therapeutic medicine (01-10-2014)“…Lithium has a narrow therapeutic index with a subtle balance between effectiveness and adverse effects. Current guidelines recommend the use of lithium as a…”
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Increased Brain Lactate During Depressive Episodes and Reversal Effects by Lithium Monotherapy in Drug-Naive Bipolar Disorder: A 3-T 1H-MRS Study
Published in Journal of clinical psychopharmacology (01-02-2017)“…Mitochondrial dysfunction and energy metabolism impairment are key components in the pathophysiology of bipolar disorder (BD) and may involve a shift from…”
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Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder
Published in European neuropsychopharmacology (01-04-2015)“…Abstract Strong evidence implicates intracellular signaling cascades dysfunction in the pathophysiology of Bipolar Disorder (BD). Regulation of AKT/mTOR…”
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Effects of lithium on oxidative stress parameters in healthy subjects
Published in Molecular medicine reports (01-03-2012)“…Increased neuronal oxidative stress (OxS) induces deleterious effects on signal transduction, structural plasticity and cellular resilience, mainly by inducing…”
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A Longitudinal (6-week) 3T (1)H-MRS Study on the Effects of Lithium Treatment on Anterior Cingulate Cortex Metabolites in Bipolar Depression
Published in European neuropsychopharmacology (01-12-2015)“…The anterior cingulate cortex (ACC) is a key area in mood regulation. To date, no longitudinal study has specifically evaluated lithium׳s effects on ACC…”
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LICAVAL: combination therapy in acute and maintenance treatment of bipolar disorder
Published in Current controlled trials in cardiovascular medicine (23-06-2010)“…The challenge of Bipolar Disorder (BD) treatment is due to the complexity of the disease. Current guidelines represent an effort to help clinicians in their…”
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Early improvement with lithium in classic mania and its association with later response
Published in Journal of affective disorders (10-01-2013)“…Abstract Objectives Despite lithium’s clinical efficacy in treating mania in bipolar disorder (BD), studies evaluating early improvement and subsequent…”
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A Longitudinal (6-week) 3T 1H-MRS Study on the Effects of Lithium Treatment on Anterior Cingulate Cortex Metabolites in Bipolar Depression
Published in European neuropsychopharmacology (01-12-2015)“…The anterior cingulate cortex (ACC) is a key area in mood regulation. To date, no longitudinal study has specifically evaluated lithium׳s effects on ACC…”
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Early improvement of psychotic symptoms with lithium monotherapy as a predictor of later response in mania
Published in Journal of psychiatric research (01-12-2012)“…Abstract Although lithium has been the first line agent in the treatment of bipolar disorder (BD), few studies have evaluated lithium's efficacy in mania with…”
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What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Published in Human brain mapping (01-01-2022)“…MRI‐derived brain measures offer a link between genes, the environment and behavior and have been widely studied in bipolar disorder (BD). However, many…”
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