Production of bacterial cellulose nanocrystals via enzymatic hydrolysis and evaluation of their coating on alginate particles formed by ionotropic gelation

Production of bacterial cellulose nanocrystals via enzymatic hydrolysis and evaluation of their coating on alginate particles formed by ionotropic gelation

This study aimed to obtain the bacterial cellulose nanocrystals (CNC) by enzymatic hydrolysis and verify the CNC application as coating material in alginate particles. Therefore, the production of CNC was carried out through two enzymatic hydrolysis methods involving a time period of 48 and 72 h. 0....

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Bibliographic Details
Published in:Carbohydrate polymer technologies and applications Vol. 2; p. 100155
Main Authors: Soeiro, Victória S., Tundisi, Louise L., Novaes, Letícia C.L., Mazzola, Priscila G., Aranha, Norberto, Grotto, Denise, Júnior, José M.O., Komatsu, Daniel, Gama, Francisco M.P., Chaud, Marco V., Jozala, Angela F.
Format: Journal Article
Language:English
Published: Elsevier Ltd 25-12-2021
Elsevier
Subjects:
Alginate particles
Bacterial cellulose
Coating
Enzyme
Ionotropic gelation
Nanocrystals
Stability
Alginate particles
Nanocrystals
Stability
Ionotropic gelation
Enzyme
Bacterial cellulose
Coating
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Summary:This study aimed to obtain the bacterial cellulose nanocrystals (CNC) by enzymatic hydrolysis and verify the CNC application as coating material in alginate particles. Therefore, the production of CNC was carried out through two enzymatic hydrolysis methods involving a time period of 48 and 72 h. 0.35 mg of dry mass of cellulose was produced approximately 1.6 × 1011 CNC/mL. The CNC obtained by enzymatic hydrolysis at 72 h (Method II) was applied to cover the alginate particles, obtained by ionotropic gelation. The CNC Zeta potential value was about +15 mV and for alginate particles -26.46 ± 1.48 mV. These results confirmed the application of CNC as coating material for alginate particles. It brings an incremental contribution to the knowledge advancement in the pharmaceutical and food area, allowing the engineering of systems to use a mixed composition of nanobiomaterials to modify the release pattern of drugs, macromolecule, nutrients, stabilizers and target specific drug release. •Enzymatic hydrolysis is a green process to obtain the bacterial cellulose nanocrystals (CNC).•The mechanical treatment improved the bacterial CNC production, influencing the parameters of size, polydispersity index (PDI), and zeta potential of the samples.•Ionotropic gelation technology was applied to obtain the alginate particles.•Bacterial CNC coated alginate particles, and this covering was a great pathway to eliminate the CNC agglomeration.•This work was established and opened a new pathway to produce and apply the bacterial CNC. [Display omitted]
ISSN:2666-8939
2666-8939
DOI:10.1016/j.carpta.2021.100155