Search Results - "Sochanowicz, Barbara"
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Ivabradine prevents deleterious effects of dopamine therapy in heart failure: No role for HCN4 overexpression
Published in Biomedicine & pharmacotherapy (01-04-2021)“…[Display omitted] •2-week dopamine infusion ↓ hemodynamics and ↑ arrhythmias in the rat heart failure.•A heart rate reducing agent, ivabradine, prevents these…”
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Silver Nanoparticles Induced Changes in DNA Methylation and Histone H3 Methylation in a Mouse Model of Breast Cancer
Published in Materials (02-06-2023)“…The importance of epigenetic changes as a measurable endpoint in nanotoxicological studies is getting more and more appreciated. In the present work, we…”
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Beneficial effects of intravenous iron therapy in a rat model of heart failure with preserved systemic iron status but depleted intracellular cardiac stores
Published in Scientific reports (25-10-2018)“…Iron deficiency (ID) commonly occurs in chronic heart failure (HF) and is associated with poor prognosis. Neither its causes nor pathophysiological…”
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Clinical and Molecular Aspects of Iron Metabolism in Failing Myocytes
Published in Life (Basel, Switzerland) (08-08-2022)“…Heart failure (HF) is a common disease that causes significant limitations on the organism’s capacity and, in extreme cases, leads to death. Clinically, iron…”
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Grey areas and open questions in neprilysin inhibition
Published in Journal of cardiology (01-04-2020)Get full text
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Searching for Optimal Prognostic Marker of Heart Failure Progression in the Era of ARNI
Published in Journal of the American College of Cardiology (09-07-2019)Get full text
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Accurate Noninvasive Assessment of Myocardial Iron Load in Advanced Heart Failure Patients
Published in Disease markers (2020)“…Background. Heart failure patients presenting with iron deficiency can benefit from systemic iron supplementation; however, there is the potential for iron…”
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Natriuretic peptides and their receptors in failing heart – Functional changes and implications for treatment
Published in International journal of cardiology (15-08-2018)“…•Heart failure leads to altered cardiac expression of natriuretic peptides on transcriptional and transcriptional level.•Expression of NPR-A and NPR-B remains…”
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9
Myocardial iron homeostasis in advanced chronic heart failure patients
Published in International journal of cardiology (09-08-2012)“…Abstract Background Although, correction of iron deficiency and/or anemia in heart failure (HF) with iron seems promising, little is known about myocardial…”
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Expression of Iron Metabolism Proteins in Patients with Chronic Heart Failure
Published in Journal of clinical medicine (05-02-2022)“…In heart failure, iron deficiency is a common comorbid disease that negatively influences exercise tolerance, number of hospitalizations and mortality rate,…”
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Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice
Published in Molecular and cellular biochemistry (01-12-2014)“…The aim of this study was to examine the possible impact of Cu,Zn-SOD deficiency on the level of epigenetic modifications in different mouse tissues, and the…”
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12
Epigenetic modifications and NF-[kappa]B pathway activity in Cu,Zn-SOD-deficient mice
Published in Molecular and cellular biochemistry (01-12-2014)“…The aim of this study was to examine the possible impact of Cu,Zn-SOD deficiency on the level of epigenetic modifications in different mouse tissues, and the…”
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Does myocardial iron load determine the severity of heart insufficiency?
Published in International journal of cardiology (01-03-2015)Get full text
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Carcinogenesis-related changes in iron metabolism in chronic obstructive pulmonary disease subjects with lung cancer
Published in Oncology letters (01-11-2018)“…Chronic obstructive pulmonary disease (COPD) is often accompanied by lung cancer. In our previous work, it was observed that matrix metalloproteinase-3 and…”
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Abstract 236: Heart Failure Remodeling: Local Endogenous Erythropoietin and Erythropoietin Receptor Expression
Published in Circulation research (03-08-2012)“…Abstract only Erythropoietin (EPO) via erythropoietin receptor (EPOR) maintains myeloid erythropoiesis, however in a failing heart (FH) it seems to exert…”
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16
Cis-9,trans-11-conjugated linoleic acid affects lipid raft composition and sensitizes human colorectal adenocarcinoma HT-29 cells to X-radiation
Published in Biochimica et biophysica acta (01-01-2013)“…Investigations concerned the mechanism of HT-29 cells radiosensitization by cis-9,trans-11-conjugated linoleic acid (c9,t11-CLA), a natural component of human…”
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Alterations in the expression of genes related to NF-κB signaling in liver and kidney of CuZnSOD-deficient mice
Published in Molecular and cellular biochemistry (01-07-2011)“…NF-κB signaling pathway plays a central role in regulation of the cellular response to stress. Among numerous factors that modulate NF-κB dependent…”
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Alterations in the expression of genes related to NF-[kappa]B signaling in liver and kidney of CuZnSOD-deficient mice
Published in Molecular and cellular biochemistry (01-07-2011)“…NF-[kappa]B signaling pathway plays a central role in regulation of the cellular response to stress. Among numerous factors that modulate NF-[kappa]B dependent…”
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Matrix metalloproteinase 3 polymorphisms as a potential marker of enhanced susceptibility to lung cancer in chronic obstructive pulmonary disease subjects
Published in Annals of Agricultural and Environmental Medicine (01-01-2014)“…Chronic obstructive pulmonary disease (COPD) is often accompanied by lung cancer. Among the genes that may play a role in the occurrence of COPD and lung…”
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Matrix metalloproteinase 3 polymorphisms as a potential marker of enhanced susceptibility to lung cancer in chronic obstructive pulmonary disease subjects
Published in Annals of Agricultural and Environmental Medicine (01-09-2014)“…[b]Introduction and objective[/b]. Chronic obstructive pulmonary disease (COPD) is often accompanied by lung cancer. Among the genes that may play a role in…”
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