Search Results - "Soca Chafre, Giovanny"
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Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications
Published in Frontiers in oncology (24-10-2023)“…Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential…”
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2
Association between CD47 expression, clinical characteristics and prognosis in patients with advanced non‐small cell lung cancer
Published in Cancer medicine (Malden, MA) (01-04-2020)“…Objective CD47 is an antiphagocytic molecule that contributes to tumor cell resistance in host immune surveillance. CD47 overexpression correlated with tumor…”
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3
Curcumin inhibits activation induced by urban particulate material or titanium dioxide nanoparticles in primary human endothelial cells
Published in PloS one (15-12-2017)“…Curcumin has protective effects against toxic agents and shows preventive properties for various diseases. Particulate material with an aerodynamic diameter of…”
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4
Genetic Ancestry Contributes to Somatic Mutations in Lung Cancers from Admixed Latin American Populations
Published in Cancer discovery (01-03-2021)“…Inherited lung cancer risk, particularly in nonsmokers, is poorly understood. Genomic and ancestry analysis of 1,153 lung cancers from Latin America revealed…”
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5
Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α
Published in Journal of immunology research (01-01-2019)“…Triple-negative breast cancer (TNBC) is one of the most aggressive tumors, with poor prognosis and high metastatic capacity. The aggressive behavior may…”
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Upregulated Nuclear Expression of Soluble Epoxide Hydrolase Predicts Poor Outcome in Breast Cancer Patients: Importance of the Digital Pathology Approach
Published in International journal of molecular sciences (01-08-2024)“…Breast cancer (BC) is the most common cancer in women, with incidence rates increasing globally in recent years. Therefore, it is important to find new…”
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Interplay between Cellular and Molecular Inflammatory Mediators in Lung Cancer
Published in Mediators of Inflammation (01-01-2016)“…Inflammation is a component of the tumor microenvironment and represents the 7th hallmark of cancer. Chronic inflammation plays a critical role in…”
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8
Mutational profile by targeted next generation sequencing of non-small cell lung cancer in the Mexican population
Published in Salud pública de México (01-05-2019)“…Targeted next-generation sequencing (t-NGS) has revolutionized clinical diagnosis allowing multiplexed detection of genomic alterations. This study evaluated…”
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Multiple Molecular Targets Associated with Genomic Instability in Lung Cancer
Published in International journal of genomics (01-01-2019)“…Lung cancer (LC) is the first cause of cancer-related deaths worldwide. Elucidating the pathogenesis of LC will give information on key elements of tumor…”
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Abstract 1849: Cellullar modifications of glucose uptake through the modulation of AMPK & EGFR signaling axes in lung cancer cell lines
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Background. The exacerbated consumption of glucose in tumor cells is a widely reported event, this metabolic modification is associated with the…”
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Abstract LB-186: Evaluation of EGFR degradation as a mechanism of tumor evasion in EGFR-TKI resistant non-small cell lung cancer (NSCLC) cells compared to EGFR-TKI sensitive cells
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract The resistance mechanisms to EGFR-TKIs in Non-Small Cell Lung Cancer (NSCLC) are not well elucidated. Here we evaluate EGFR degradation as a mechanism…”
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Clinicopathological features related to survival in adenocarcinoma of the Vaterian system in a Mexican population
Published in Human pathology (01-01-2019)“…Adenocarcinomas of the ampulla of Vater account for 0.5% of malignant neoplasms of the gastrointestinal tract and 6% to 20% of malignant periampullary…”
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Abstract IA-07: Genetic ancestry and lung cancer somatic mutations in patients of Latin American descent: Etiology and treatment implications
Published in Cancer epidemiology, biomarkers & prevention (01-01-2022)“…Abstract Inherited lung cancer risk, particularly in nonsmokers, is poorly understood. In particular, the frequency of somatic EGFR and KRAS mutations in lung…”
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Different mutation profiles and clinical characteristics among Hispanic patients with non-small cell lung cancer could explain the “Hispanic paradox”
Published in Lung cancer (Amsterdam, Netherlands) (01-11-2015)“…Highlights • It has been reported an advantage in overall survival in Hispanic populations. • We analyzed an Hispanic cohort of NSCLC patients cohort to…”
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Abstract 3554: The combined effect of afatinib and metformin on glycolytic regulation in EGFR-mutant non-small cell lung cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Background: The metabolic features of cancer cells allows their rapid proliferation and escape from apoptosis. Novel targeted treatments are being…”
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Airborne particulate matter upregulates expression of early and late adhesion molecules and their receptors in a lung adenocarcinoma cell line
Published in Environmental research (01-07-2021)“…Epidemiological evidence associates chronic exposure to particulate matter (PM) with respiratory damage and lung cancer. Inhaled PM may induce systemic effects…”
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Etiology of epilepsy in Mexico: results from the national multi-centre register
Published in Revista de neurologiá (01-10-2024)“…Epilepsy affects millions of people and its geographical patterns are usually linked to etiological aspects. Our objective was to describe main etiologies of…”
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FAACT-Anorexia Cachexia Scale: Cutoff Value for Anorexia Diagnosis in Advanced Non-Small Cell Lung Cancer Patients
Published in Nutrition and cancer (03-04-2019)“…Lung cancer (LC) has a high rate of anorexia, which negatively affects quality-of-life and prognosis; however prevalence values may vary as per diagnostic…”
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Abstract C024: Evaluation of PI3K/AKT/mTOR pathway signaling as a prognostic indicator in Hispanic Mexican women with breast cancer
Published in Cancer epidemiology, biomarkers & prevention (21-09-2024)“…Abstract Breast cancer (BC) is among the most commonly diagnosed cancer in women and a leading cause of cancer death worldwide. Hispanic/Latina women represent…”
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Targeted next generation sequencing identified a high frequency genetic mutated profile in wood smoke exposure-related lung adenocarcinoma patients
Published in Oncotarget (17-07-2018)“…Wood smoke exposure (WSE) has been associated with an increased risk of lung cancer development. WSE has been related with high frequency of EGFR mutations and…”
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