Comparison of two doses of metformin (2.5 and 1.5 g/day) for the treatment of polycystic ovary syndrome and their effect on body mass index and waist circumference

Comparison of two doses of metformin (2.5 and 1.5 g/day) for the treatment of polycystic ovary syndrome and their effect on body mass index and waist circumference

Fifty-six women with body mass index (BMI) greater than 27 were randomly divided into two groups receiving different doses of metformin (2.5 g and 1.5 g/day) for the treatment of polycystic ovary syndrome to assess its effects on BMI and waist circumference. Although after 6 months of treatment both...

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Bibliographic Details
Published in:Fertility and sterility Vol. 88; no. 2; pp. 510 - 512
Main Authors: Bruno, Ricardo Vasconcellos, de Ávila, Márcio Augusto Pinto, Neves, Fernanda Baleeiro, Nardi, Antonio Egidio, Crespo, Clícia Márcia Santos, Sobrinho, Antonio Tavares Carneiro
Format: Journal Article
Language:English
Published: New York, NY Elsevier Inc 01-08-2007
Elsevier Science
Subjects:
Adult
Biological and medical sciences
Body Mass Index
Body Weight - drug effects
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Hypoglycemic Agents - administration & dosage
Insulin Resistance
Internal Medicine
Medical sciences
Metformin - administration & dosage
Non tumoral diseases
Obstetrics and Gynecology
Polycystic Ovary Syndrome - drug therapy
Waist-Hip Ratio
Andrology
Anthropometry
Gynecology
Female sterility
Corporal biometry
Polycystic ovary
Female genital diseases
Ovarian diseases
Body mass index
Waist circumference
Biguanides
Treatment
Fertility
Cyst
Benign neoplasm
Metformin
Dose
Comparative study
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Summary:Fifty-six women with body mass index (BMI) greater than 27 were randomly divided into two groups receiving different doses of metformin (2.5 g and 1.5 g/day) for the treatment of polycystic ovary syndrome to assess its effects on BMI and waist circumference. Although after 6 months of treatment both groups had a significant reduction in those indices, the intergroup variation proved the higher dose to be more efficient.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2006.11.133