Search Results - "Sobota, Malgorzata"

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    Evolutionary trade-off between heat shock resistance, growth at high temperature, and virulence expression in Salmonella Typhimurium by Berdejo, Daniel, Mortier, Julien, Cambré, Alexander, Sobota, Malgorzata, Van Eyken, Ronald, Kim, Tom Dongmin, Vanoirbeek, Kristof, García Gonzalo, Diego, Pagán, Rafael, Diard, Médéric, Aertsen, Abram

    Published in mBio (13-03-2024)
    “…Understanding the evolutionary dynamics of foodborne pathogens throughout our food production chain is of utmost importance. In this study, we reveal that…”
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    Journal Article
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    Two Distinct DNA Binding Modes Guide Dual Roles of a CRISPR-Cas Protein Complex by Blosser, Timothy R., Loeff, Luuk, Westra, Edze R., Vlot, Marnix, Künne, Tim, Sobota, Małgorzata, Dekker, Cees, Brouns, Stan J.J., Joo, Chirlmin

    Published in Molecular cell (02-04-2015)
    “…Small RNA-guided protein complexes play an essential role in CRISPR-mediated immunity in prokaryotes. While these complexes initiate interference by flagging…”
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    Journal Article
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    Target-enriched nanopore sequencing and de novo assembly reveals co-occurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells by Geng, Keyi, Merino, Lara G, Wedemann, Linda, Martens, Aniek, Sobota, Małgorzata, Sanchez, Yerma P, Søndergaard, Jonas Nørskov, White, Robert J, Kutter, Claudia

    Published in Genome research (01-10-2022)
    “…The CRISPR-Cas9 system is widely used to permanently delete genomic regions via dual guide RNAs. Genomic rearrangements induced by CRISPR-Cas9 can occur, but…”
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    Journal Article