Search Results - "Sobolewski, Anastasia"

IL-6 Signaling Regulates Small Intestinal Crypt Homeostasis by Jeffery, Victoria, Goldson, Andrew J, Dainty, Jack R, Chieppa, Marcello, Sobolewski, Anastasia

“…Gut homeostasis is a tightly regulated process requiring finely tuned complex interactions between different cell types, growth factors, or cytokines and their…”
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Quercetin Exposure Suppresses the Inflammatory Pathway in Intestinal Organoids from Winnie Mice by Dicarlo, Manuela, Teti, Gabriella, Verna, Giulio, Liso, Marina, Cavalcanti, Elisabetta, Sila, Annamaria, Raveenthiraraj, Sathuwarman, Mastronardi, Mauro, Santino, Angelo, Serino, Grazia, Lippolis, Antonio, Sobolewski, Anastasia, Falconi, Mirella, Chieppa, Marcello

“…Inflammatory bowel diseases (IBDs) are chronic and relapsing immune disorders that result, or possibly originate, from epithelial barrier defects. Intestinal…”
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A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions by Liso, Marina, De Santis, Stefania, Scarano, Aurelia, Verna, Giulio, Dicarlo, Manuela, Galleggiante, Vanessa, Campiglia, Pietro, Mastronardi, Mauro, Lippolis, Antonio, Vacca, Mirco, Sobolewski, Anastasia, Serino, Grazia, Butelli, Eugenio, De Angelis, Maria, Martin, Cathie, Santino, Angelo, Chieppa, Marcello

“…Inflammatory bowel diseases (IBD) are debilitating chronic inflammatory disorders that develop as a result of a defective immune response toward intestinal…”
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Secretory Leukoprotease Inhibitor (Slpi) Expression Is Required for Educating Murine Dendritic Cells Inflammatory Response Following Quercetin Exposure by De Santis, Stefania, Galleggiante, Vanessa, Scandiffio, Letizia, Liso, Marina, Sommella, Eduardo, Sobolewski, Anastasia, Spilotro, Vito, Pinto, Aldo, Campiglia, Pietro, Serino, Grazia, Santino, Angelo, Notarnicola, Maria, Chieppa, Marcello

“…Dendritic cells' (DCs) ability to present antigens and initiate the adaptive immune response confers them a pivotal role in immunological defense against…”
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Eotaxin-1/CC Chemokine Ligand 11: A Novel Eosinophil Survival Factor Secreted by Human Pulmonary Artery Endothelial Cells by Farahi, Neda, Cowburn, Andrew S, Upton, Paul D, Deighton, John, Sobolewski, Anastasia, Gherardi, Ermanno, Morrell, Nicholas W, Chilvers, Edwin R

“…Airway eosinophilia plays a major role in the pathogenesis of asthma with the inhibition of apoptosis by GM-CSF and IL-5 proposed as a mechanism underlying…”
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Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase by Sobolewski, Anastasia, Jourdan, Karen B, Upton, Paul D, Long, Lu, Morrell, Nicholas W

“…Long-term infusion of prostacyclin, or its analogs, is an effective treatment for severe pulmonary arterial hypertension. However, dose escalation is often…”
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M1 and M2 Macrophages Differentially Regulate Colonic Crypt Renewal by Raveenthiraraj, Sathuwarman, Awanis, Griselda, Chieppa, Marcello, O’Connell, Amy E, Sobolewski, Anastasia

“…Abstract Background The colonic epithelium is the most rapidly renewing tissue in the body and is organized into a single cell layer of invaginations called…”
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A Specific Mutation in Muc2 Determines Early Dysbiosis in Colitis-Prone Winnie Mice by Liso, Marina, De Santis, Stefania, Verna, Giulio, Dicarlo, Manuela, Calasso, Maria, Santino, Angelo, Gigante, Isabella, Eri, Rajaraman, Raveenthiraraj, Sathuwarman, Sobolewski, Anastasia, Palmitessa, Valeria, Lippolis, Antonio, Mastronardi, Mauro, Armentano, Raffaele, Serino, Grazia, De Angelis, Maria, Chieppa, Marcello

“…Abstract Background Inflammatory bowel disease (IBD), including Crohn disease (CD) and ulcerative colitis (UC), is a multifactorial disorder characterized by…”
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Ferrocenyl β-Diketonate Compounds: Extended Ring Systems for Improved Anticancer Activity by Hofmann, Benjamin J, Aljohani, Enas T, Cicovacki, Natalia, Lee, Ivan, Warren, Derek T, Sobolewski, Anastasia, Stringer, Tameryn, Lord, Rianne M

“…A library of ferrocenyl β-diketonate compounds with varying degrees of aromatic functionality have been synthesized and fully characterized. This includes…”
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A highly photostable and versatile two-photon fluorescent probe for the detection of a wide range of intracellular nitric oxide concentrations in macrophages and endothelial cells by Arnau del Valle, Carla, Williams, Lewis, Thomas, Paul, Johnson, Robert, Raveenthiraraj, Sathuwarman, Warren, Derek, Sobolewski, Anastasia, Muñoz, María Paz, Galindo, Francisco, Marín, María J.

“…Nitric oxide (NO) is involved in many biological processes affecting the cardiovascular, nervous and immune systems. Intracellular NO can be monitored using…”
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HGF/c-Met/β1-integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells by Awanis, Griselda, Banerjee, Salonee, Johnson, Robert, Raveenthiraraj, Sathuwarman, Elmeligy, Aya, Warren, Derek, Gavrilovic, Jelena, Sobolewski, Anastasia

“…Tunneling nanotubes (TNTs) are thin cytoplasmic extensions involved in long-distance intercellular communication and can transport intracellular organelles and…”
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Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity by Walmsley, Sarah R., Print, Cristin, Farahi, Neda, Peyssonnaux, Carole, Johnson, Randall S., Cramer, Thorsten, Sobolewski, Anastasia, Condliffe, Alison M., Cowburn, Andrew S., Johnson, Nicola, Chilvers, Edwin R.

“…Neutrophils are key effector cells of the innate immune response and are required to migrate and function within adverse microenvironmental conditions. These…”
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Interleukin-6 signaling regulates small intestinal crypt homeostasis by Jeffery, Victoria, Goldson, Andrew J., Dainty, Jack R., Chieppa, Marcello, Sobolewski, Anastasia

“…Gut homeostasis is a tightly regulated process requiring finely-tuned complex interactions between different cell types, growth factors or cytokines and their…”
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Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium by Reynolds, Amy, Wharton, Natalia, Parris, Alyson, Mitchell, Esther, Sobolewski, Anastasia, Kam, Christy, Bigwood, Loren, El Hadi, Ahmed, Münsterberg, Andrea, Lewis, Michael, Speakman, Christopher, Stebbings, William, Wharton, Richard, Sargen, Kevin, Tighe, Richard, Jamieson, Crawford, Hernon, James, Kapur, Sandeep, Oue, Naohide, Yasui, Wataru, Williams, Mark R

“…A defining characteristic of the human intestinal epithelium is that it is the most rapidly renewing tissue in the body. However, the processes underlying…”
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Luminal microbes promote monocyte-stem cell interactions across a healthy colonic epithelium by Skoczek, Dagmara A, Walczysko, Petr, Horn, Nikki, Parris, Alyson, Clare, Simon, Williams, Mark R, Sobolewski, Anastasia

“…The intestinal epithelium forms a vital barrier between luminal microbes and the underlying mucosal immune system. Epithelial barrier function is maintained by…”
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Tu1849 Juxtapositioning of Neutrophils and Macrophages With Colonic Stem Cells, and Mobilisation of Neutrophils to the Surface Epithelium, Following Luminal Microbial Input by Dyjach, Dagmara, Walczysko, Petr, Horn, Nikki, Williams, Mark, Sobolewski, Anastasia

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Mutations in Bone Morphogenetic Protein Type II Receptor Cause Dysregulation of Id Gene Expression in Pulmonary Artery Smooth Muscle Cells: Implications for Familial Pulmonary Arterial Hypertension by Yang, Jun, Davies, Rachel J, Southwood, Mark, Long, Lu, Yang, Xudong, Sobolewski, Anastasia, Upton, Paul D, Trembath, Richard C, Morrell, Nicholas W

“…Heterozygous germ line mutations in the gene encoding the bone morphogenetic protein (BMP) type II receptor occur in more than 80% of patients with familial…”
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Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue by Sobolewski, Anastasia, Rudarakanchana, Nung, Upton, Paul D., Yang, Jun, Crilley, Trina K., Trembath, Richard C., Morrell, Nicholas W.

“…Heterozygous germline mutations in the gene encoding the bone morphogenetic protein type II receptor cause familial pulmonary arterial hypertension (PAH). We…”
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908 Prostaglandin E2 Promotes Mouse Colonic Organoid Growth and Human Colonic Crypt Stem/Progenitor Cell Proliferation by Sobolewski, Anastasia, Lambert, Alexander, Hadi, Ahmed El, Parris, Alyson, Wharton, Natalia, Sargen, Kevin, Prior, Alison, Wharton, Richard, Speakman, Christopher, Lewis, Michael P, Williams, Mark

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Su1734 Canonical Wnt Signals Combined With Suppressed TGFbeta/BMP Pathways Promote Renewal of the Native Human Colonic Epithelium by Wharton, Natalia, Parris, Alyson, Reynolds, Amy, Mitchell, Esther M, Sobolewski, Anastasia, El Hadi, Ahmed, Lewis, Michael P, Speakman, Chris T, Stebbings, William, Wharton, Richard, Sargen, Kevin, Tighe, Richard, Jamieson, Crawford P, Hernon, James, Kapur, Sandeep, Williams, Mark

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