Search Results - "Sobolewska, Alicja"

Mitigation of aging-related plasticity decline through taurine supplementation and environmental enrichment by Gawryluk, Aleksandra, Cybulska-Klosowicz, Anita, Charzynska, Agata, Zakrzewska, Renata, Sobolewska, Alicja, Kossut, Malgorzata, Liguz-Lecznar, Monika

“…Aging-related biochemical changes in nerve cells lead to dysfunctional synapses and disrupted neuronal circuits, ultimately affecting vital processes such as…”
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Non-parametric analysis of neurochemical effects and Arc expression in amphetamine-induced 50-kHz ultrasonic vocalization by Hamed, Adam, Daszczuk, Patrycja, Kursa, Miron Bartosz, Turzyńska, Danuta, Sobolewska, Alicja, Lehner, Małgorzata, Boguszewski, Paweł M., Szyndler, Janusz

“…•Re-exposure to amphetamine increased 50-kHz USVs comparing to control.•50-kHz USVs do not correlate with distance covered by the investigated…”
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Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions by Rozycka, Aleksandra, Charzynska, Agata, Misiewicz, Zuzanna, Maciej Stepniewski, Tomasz, Sobolewska, Alicja, Kossut, Malgorzata, Liguz-Lecznar, Monika

“…Molecular synaptic aging perturbs neurotransmission and decreases the potential for neuroplasticity. The direction and degree of changes observed in aging are…”
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Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats by Skórzewska, Anna, Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Turzyńska, Danuta, Sobolewska, Alicja, Krząścik, Paweł, Płaźnik, Adam

“…The aim of this study was to examine the effects of benzodiazepine (midazolam) administration on rat conditioned fear responses and on local brain activity…”
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Mapping of c-Fos expression in the rat brain during the evolution of pentylenetetrazol-kindled seizures by Szyndler, Janusz, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Taracha, Ewa, Skórzewska, Anna, Lehner, Małgorzata, Bidziński, Andrzej, Hamed, Adam, Wisłowska-Stanek, Aleksandra, Krząścik, Paweł, Płaźnik, Adam

“…Abstract c-Fos protein immunocytochemistry was used to map the brain structures recruited during the evolution of seizures that follows repeated administration…”
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Time course of changes in the concentrations of amino acids in the brain structures of pentylenetetrazole-kindled rats by Maciejak, Piotr, Szyndler, Janusz, Turzyńska, Danuta, Sobolewska, Alicja, Bidziński, Andrzej, Kołosowska, Karolina, Płaźnik, Adam

“…Abstract The results showed that the development of seizures (pentylenetetrazole, PTZ-induced kindling; PTZ was administered to rats at a subconvulsive dose of…”
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Changes in the concentration of amino acids in the hippocampus of pentylenetetrazole-kindled rats by Szyndler, Janusz, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Lehner, Małgorzata, Taracha, Ewa, Walkowiak, Jerzy, Skórzewska, Anna, Wisłowska-Stanek, Aleksandra, Hamed, Adam, Bidziński, Andrzej, Płaźnik, Adam

“…It is not well recognized how disturbances in the local metabolism of some amino acids, especially glutamate and GABA, may lead to seizures. In the presented…”
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Altered glutamate/GABA equilibrium in aged mice cortex influences cortical plasticity by Liguz-Lecznar, Monika, Lehner, Malgorzata, Kaliszewska, Aleksandra, Zakrzewska, Renata, Sobolewska, Alicja, Kossut, Malgorzata

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The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration by Maciejak, Piotr, Szyndler, Janusz, Turzyńska, Danuta, Sobolewska, Alicja, Taracha, Ewa, Skórzewska, Anna, Lehner, Małgorzata, Bidziński, Andrzej, Hamed, Adam, Wisłowska-Stanek, Aleksandra, Płaźnik, Adam

“…Abstract Considering the contribution of hippocampal formation and glutamate-mediated signalling to epileptogenesis, we investigated the effects of group III…”
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The expression of c-Fos and colocalisation of c-Fos and glucocorticoid receptors in brain structures of low and high anxiety rats subjected to extinction trials and re-learning of a conditioned fear response by Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Taracha, Ewa, Maciejak, Piotr, Szyndler, Janusz, Skórzewska, Anna, Turzyńska, Danuta, Sobolewska, Alicja, Hamed, Adam, Bidziński, Andrzej, Płaźnik, Adam

“…We designed an animal model to examine the mechanisms of differences in individual responses to aversive stimuli. We used the rat freezing response in the…”
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The effects of acute corticosterone administration on anxiety, endogenous corticosterone, and c-Fos expression in the rat brain by Skórzewska, Anna, Bidziński, Andrzej, Lehner, Małgorzata, Turzyńska, Danuta, Sobolewska, Alicja, Hamed, Adam, Szyndler, Janusz, Maciejak, Piotr, Plaznik, Adam

“…The effects of acute pretreatment of rats with corticosterone (5 and 20 mg/kg, s.c.) on emotional behavior, expression of c-Fos protein in brain structures,…”
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Long-term disruption of tissue levels of glutamate and glutamatergic neurotransmission neuromodulators, taurine and kynurenic acid induced by amphetamine by Taracha, Ewa, Czarna, Magdalena, Turzyńska, Danuta, Sobolewska, Alicja, Maciejak, Piotr

“…Rationale Chronic amphetamine (AMPH) use leading to addiction results in adaptive changes within the central nervous system that persist well beyond the drug’s…”
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Increased Hippocampal Afterdischarge Threshold in Ketogenic Diet is Accompanied by Enhanced Kynurenine Pathway Activity by Osuch, Bartosz, Kołosowska, Karolina, Chmielewska, Natalia, Turzyńska, Danuta, Sobolewska, Alicja, Szyndler, Janusz, Maciejak, Piotr

“…The efficacy of a ketogenic diet (KD) in controlling seizure has been shown in many experimental and clinical studies, however, its mechanism of action still…”
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The effect of valproate on the amino acids, monoamines, and kynurenic acid concentrations in brain structures involved in epileptogenesis in the pentylenetetrazol-kindled rats by Wisłowska-Stanek, Aleksandra, Turzyńska, Danuta, Sobolewska, Alicja, Kołosowska, Karolina, Szyndler, Janusz, Skórzewska, Anna, Maciejak, Piotr

“…The study aimed to assess the influence of a single valproate (VPA) administration on inhibitory and excitatory neurotransmitter concentrations in the brain…”
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The role of REST/NRSF, TrkB and BDNF in neurobiological mechanisms of different susceptibility to seizure in a PTZ model of epilepsy by Chmielewska, Natalia, Wawer, Adriana, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Skórzewska, Anna, Osuch, Bartosz, Płaźnik, Adam, Szyndler, Janusz

“…•REST/NRSF act to confer a neuroprotection against seizure.•TrkB play a pivotal role during epileptogenesis.•Modulation of REST/NRSF-TrkB may be potential…”
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Altered glutamate/GABA equilibrium in aged mice cortex influences cortical plasticity by Liguz-Lecznar, Monika, Lehner, Malgorzata, Kaliszewska, Aleksandra, Zakrzewska, Renata, Sobolewska, Alicja, Kossut, Malgorzata

“…Age-related molecular changes in the synapse can cause plasticity decline. We found an impairment of experience-dependent cortical plasticity is induced by…”
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Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours by Skórzewska, Anna, Lehner, Małgorzata, Wisłowska-Stanek, Aleksandra, Turzyńska, Danuta, Sobolewska, Alicja, Krząścik, Paweł, Szyndler, Janusz, Maciejak, Piotr, Chmielewska, Natalia, Kołosowska, Karolina, Płaźnik, Adam

“…•Selection for resistant PTSD(-) and susceptible PTSD(+) rats based on fear response.•PTSD(+) rats had decreased plasma corticosterone level.•PTSD(+) rats had…”
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Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease by Joniec-Maciejak, Ilona, Wawer, Adriana, Turzyńska, Danuta, Sobolewska, Alicja, Maciejak, Piotr, Szyndler, Janusz, Mirowska-Guzel, Dagmara, Płaźnik, Adam

“…Parkinson's disease (PD) is a progressive neurodegenerative process leading to the loss of dopaminergic neurons and their projections…”
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The role of interleukin-1β in the pentylenetetrazole-induced kindling of seizures, in the rat hippocampus by Kołosowska, Karolina, Maciejak, Piotr, Szyndler, Janusz, Turzyńska, Danuta, Sobolewska, Alicja, Płaźnik, Adam

“…Because the contribution of inflammatory mediators to seizure disorders is unclear, we investigated the changes in the expression of interleukin-1β (IL-β) and…”
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The role of UCH-L1, MMP-9, and GFAP as peripheral markers of different susceptibility to seizure development in a preclinical model of epilepsy by Chmielewska, Natalia, Maciejak, Piotr, Turzyńska, Danuta, Sobolewska, Alicja, Wisłowska-Stanek, Aleksandra, Kołosowska, Karolina, Płaźnik, Adam, Szyndler, Janusz

“…In our study, we assessed the potency of the brain-derived proteins ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), matrix metalloproteinase 9 (MMP-9), glial…”
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