Search Results - "Sobolev, Irina A."
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DNA Sequencing: Modular Primers Assembled From a Library of Hexamers or Pentamers
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1993)“…Here we report a striking effect displayed by "modular primers," which consist of hexamer or pentamer oligonucleotide modules base-stacked to each other upon…”
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Interdependence between DNA template secondary structure and priming efficiencies of short primers
Published in Nucleic acids research (01-12-1998)“…Here we analyze the effect of DNA folding on the performance of short primers and describe a simple technique for assessing hitherto uncertain values of…”
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Journal Article -
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On the mechanism of the modular primer effect
Published in Nucleic acids research (11-08-1995)“…Modular primers are strings of three contiguously annealed unligated oligonucleotides (modules) as short as 5- or 6-mers, selected from a presyntheslzed…”
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DNA sequencing using differential extension with nucleotide subsets (DENS)
Published in Nucleic acids research (15-02-1997)“…Here we describe template directed enzymatic synthesis of unique primers, avoiding the chemical synthesis step in primer walking. We have termed this…”
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Journal Article