Search Results - "Sobo, Matthew"

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells by Lin, Li, Hutzen, Brian, Li, Pui-Kai, Ball, Sarah, Zuo, Mingxin, DeAngelis, Stephanie, Foust, Elizabeth, Sobo, Matthew, Friedman, Lauren, Bhasin, Deepak, Cen, Ling, Li, Chenglong, Lin, Jiayuh

“…Constitutive activation of signal transducer and activator of transcription 3 (STAT3) signaling is frequently detected in cancer, promoting its emergence as a…”
Get full text

Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma by Sengupta, Satarupa, Senthil Kumar, Shiva, Bondra, Kathryn, Sobo, Matthew, Mo, Xiaokui, Drissi, Rachid

“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Previous studies have elucidated the genomic landscape of MB leading to the…”
Get full text

New curcumin analogues exhibit enhanced growth‐suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells by Lin, Li, Hutzen, Brian, Ball, Sarah, Foust, Elizabeth, Sobo, Matthew, Deangelis, Stephanie, Pandit, Bulbul, Friedman, Lauren, Li, Chenglong, Li, Pui‐Kai, Fuchs, James, Lin, Jiayuh

“…Curcumin, the active component of turmeric, has been shown to protect against carcinogenesis and prevent tumor development in cancer. To enhance its potency,…”
Get full text

Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors by Sengupta, Satarupa, Sobo, Matthew, Lee, Kyungwoo, Senthil Kumar, Shiva, White, Angela R, Mender, Ilgen, Fuller, Christine, Chow, Lionel M L, Fouladi, Maryam, Shay, Jerry W, Drissi, Rachid

“…Brain tumors remain the leading cause of cancer-related deaths in children and often are associated with long-term sequelae among survivors of current…”
Get full text

A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas by Hummel, Trent R., Salloum, Ralph, Drissi, Rachid, Kumar, Shiva, Sobo, Matthew, Goldman, Stewart, Pai, Ahna, Leach, James, Lane, Adam, Pruitt, David, Sutton, Mary, Chow, Lionel M., Grimme, Laurie, Doughman, Renee, Backus, Lori, Miles, Lili, Stevenson, Charles, Fouladi, Maryam, DeWire, Mariko

“…Although bevacizumab has not proven effective in adults with newly diagnosed high-grade gliomas (HGG), feasibility in newly diagnosed children with diffuse…”
Get full text

EPT-12TARGETING TELOMERES TO TREAT THERAPY-RESISTANT PEDIATRIC BRAIN TUMORS by Sengupta, Satarupa, Sobo, Matthew, Kumar, Shiva, Mender, Ilgen, Shay, Jerry W., Drissi, Rachid

Get full text

Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas by HUTZEN, Brian, FRIEDMAN, Lauren, SOBO, Matthew, LI LIN, LING CEN, DE ANGELIS, Stephanie, YAMAKOSHI, Hiroyuki, SHIBATA, Hiroyuki, IWABUCHI, Yoshiharu, LIN, Jiayuh

“…Curcumin has numerous anti-carcinogenic properties, but low bioavailability prevents its use in chemotherapeutic applications. One strategy for circumventing…”
Get full text

Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas by Dorris, Kathleen, Sobo, Matthew, Onar-Thomas, Arzu, Panditharatna, Eshini, Stevenson, Charles B., Gardner, Sharon L., DeWire, Mariko D., Pierson, Christopher R., Olshefski, Randal, Rempel, Sandra A., Goldman, Stewart, Miles, Lili, Fouladi, Maryam, Drissi, Rachid

“…Children with high-grade glioma, including diffuse intrinsic pontine glioma (DIPG), have a poor prognosis despite multimodal therapy. Identifying novel…”
Get full text

MB-53hTERT EXPRESSION AND REGULATION IN PEDIATRIC MEDULLOBLASTOMA (MB) by Salloum, Ralph, author, co-first, Sobo, Matthew, Cobb, Patricia, Hovestadt, Volker, Ramaswamy, Vijay, Remke, Marc, Hoffman, Lindsey, Dexheimer, Phillip, Margol, Ashley, Stevenson, Charles, Asgharzadeh, Shahab, Goldman, Stewart, Miles, Lili, Huang, Jie, von Hoff, Katja, Rutkowski, Stefan, Onar-Thomas, Arzu, Tabori, Uri, Taylor, Michael, Pfister, Stefan, Fouladi, Maryam, Drissi, Rachid

Get full text

Erratum to: Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas by Dorris, Kathleen, Sobo, Matthew, Onar-Thomas, Arzu, Panditharatna, Eshini, Stevenson, Charles B., Gardner, Sharon L., DeWire, Mariko D., Pierson, Christopher R., Olshefski, Randal, Rempel, Sandra A., Goldman, Stewart, Miles, Lili, Fouladi, Maryam, Drissi, Rachid

Get full text

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells1,2 by Lin, Li, Hutzen, Brian, Li, Pui-Kai, Ball, Sarah, Zuo, Mingxin, DeAngelis, Stephanie, Foust, Elizabeth, Sobo, Matthew, Friedman, Lauren, Bhasin, Deepak, Cen, Ling, Li, Chenglong, Lin, Jiayuh

“…Constitutive activation of signal transducer and activator of transcription 3 (STAT3) signaling is frequently detected in cancer, promoting its emergence as a…”
Get full text