Search Results - "Sobkowiak, Michal"
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Mycobiota profile of oral fungal infections in head and neck cancer patients receiving radiotherapy: A 6-year retrospective MALDI-TOF mass spectrometry study
Published in Oral oncology (01-11-2023)“…OBJECTIVESHead and neck cancer (HNC) impairs patient immunity and increases susceptibility to oral fungal infections (OFIs). Effectively treating such…”
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In Situ Detection of MAIT Cells and MR1-Expressing Cells in Tissue Biopsies Utilizing Immunohistochemistry
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…The mucosa-associated invariant T (MAIT) cells are innate-like T cells that recognize microbial vitamin B2 metabolites presented via MR1, a MHC-I-related…”
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SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Published in ACS chemical neuroscience (07-11-2024)“…The corona virus (SARS-CoV-2) pandemic and the resulting long-term neurological complications in patients, known as long COVID, have renewed interest in the…”
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Prevalence of oral human papillomavirus infection among youth, Sweden
Published in Emerging infectious diseases (01-09-2012)“…Human papillomavirus (HPV) causes cervical, head, and neck cancers. We studied 483 patients at a youth clinic in Stockholm, Sweden, and found oral HPV…”
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Human papillomavirus (HPV) 16 E6 variants in tonsillar cancer in comparison to those in cervical cancer in Stockholm, Sweden
Published in PloS one (27-04-2012)“…Human papillomavirus (HPV), especially HPV16, is associated with the development of both cervical and tonsillar cancer and intratype variants in the amino acid…”
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Persistence of salivary antibody responses after COVID-19 vaccination is associated with oral microbiome variation in both healthy and people living with HIV
Published in Frontiers in immunology (10-01-2023)“…Coevolution of microbiome and immunity at mucosal sites is essential for our health. Whether the oral microbiome, the second largest community after the gut,…”
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Tissue‐resident MAIT cell populations in human oral mucosa exhibit an activated profile and produce IL‐17
Published in European journal of immunology (01-01-2019)“…Mucosa‐associated invariant T (MAIT) cells are unconventional T lymphocytes defined by their innate‐like characteristics and broad antimicrobial…”
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Technical Advance: Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity
Published in Journal of leukocyte biology (01-07-2016)Get full text
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Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells
Published in European journal of immunology (01-03-2022)“…Herpes simplex virus type 1 (HSV‐1) infects and persists in most of the human population. Interleukin‐15 (IL‐15) has an important role in the activation of…”
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Expansion of donor-unrestricted MAIT cells with enhanced cytolytic function suitable for TCR redirection
Published in JCI insight (08-03-2021)“…Progress in our understanding of MR1-restricted mucosa-associated invariant T (MAIT) cells has raised interest in harnessing these cells for immunotherapy. The…”
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Clinical Microbial Identification of Severe Oral Infections by MALDI-TOF Mass Spectrometry in Stockholm County: an 11-Year (2010 to 2020) Epidemiological Investigation
Published in Microbiology spectrum (21-12-2022)“…Growing evidence suggests that oral infections can modify the course of systemic diseases. To date, epidemiological data on microbial oral infections are…”
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Factors Influencing Functional Heterogeneity in Human Mucosa-Associated Invariant T Cells
Published in Frontiers in immunology (10-07-2018)“…Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that recognize microbial riboflavin metabolites presented by the monomorphic…”
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Human MAIT‐cell responses to Escherichia coli: activation, cytokine production, proliferation, and cytotoxicity
Published in Journal of leukocyte biology (01-07-2016)“…A tool‐kit of adapted and optimized methods allowing for detailed functional examination of human MAIT cells responding to bacterial antigen. Mucosa‐associated…”
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Circulating and Salivary Antibodies to Fusobacterium nucleatum Are Associated With Cystic Pancreatic Neoplasm Malignancy
Published in Frontiers in immunology (2020)“…Intraductal papillary mucinous neoplasms (IPMNs) are cystic precursor lesions to pancreatic cancer. The presence of oral microbes in pancreatic tissue or cyst…”
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Isolation of pancreatic microbiota from cystic precursors of pancreatic cancer with intracellular growth and DNA damaging properties
Published in Gut microbes (01-01-2021)“…Emerging research suggests gut microbiome may play a role in pancreatic cancer initiation and progression, but cultivation of the cancer microbiome remains…”
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Mucosal-associated invariant T cells and oral microbiome in persistent apical periodontitis
Published in International journal of oral science (09-05-2019)“…Opportunistic bacteria in apical periodontitis (AP) may pose a risk for systemic dissemination. Mucosal-associated invariant T (MAIT) cells are innate-like T…”
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Human MAIT cells endowed with HBV specificity are cytotoxic and migrate towards HBV-HCC while retaining antimicrobial functions
Published in JHEP reports (01-08-2021)“…Virus-specific T cell dysfunction is a common feature of HBV-related hepatocellular carcinoma (HBV-HCC). Conventional T (ConT) cells can be redirected towards…”
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Chronic Viral Liver Diseases: Approaching the Liver Using T Cell Receptor-Mediated Gene Technologies
Published in Cells (Basel, Switzerland) (16-06-2020)“…Chronic infection with viral hepatitis is a major risk factor for liver injury and hepatocellular carcinoma (HCC). One major contributing factor to the…”
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Salivary IgG to SARS-CoV-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals
Published in Med (New York, N.Y. : Online) (11-02-2022)“…Immunocompromised individuals are highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Whether vaccine-induced…”
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The viral protein corona directs viral pathogenesis and amyloid aggregation
Published in Nature communications (27-05-2019)“…Artificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly influences their bioactivity. As nanosized obligate…”
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