Search Results - "Sobieski, Michael A"

Rotary pump speed modulation for generating pulsatile flow and phasic left ventricular volume unloading in a bovine model of chronic ischemic heart failure by Soucy, Kevin G., PhD, Giridharan, Guruprasad A., PhD, Choi, Young, BS, Sobieski, Michael A., RN, CCP, Monreal, Gretel, PhD, Cheng, Allen, MD, Schumer, Erin, MD, Slaughter, Mark S., MD, Koenig, Steven C., PhD

“…Background Rotary blood pumps operate at a constant speed (rpm) that diminishes vascular pulsatility and variation in ventricular end-systolic and…”
Get full text

Defining pulsatility during continuous-flow ventricular assist device support by Soucy, Kevin G., PhD, Koenig, Steven C., PhD, Giridharan, Guruprasad A., PhD, Sobieski, Michael A., RN, CCP, Slaughter, Mark S., MD

“…Continuous-flow ventricular assist devices (CVADs) have gained widespread use as an effective clinical therapy for patients with advanced-stage heart failure…”
Get full text

Role of RBM25/LUC7L3 in Abnormal Cardiac Sodium Channel Splicing Regulation in Human Heart Failure by GE GAO, AN XIE, SOBIESKI, Michael A, BHAT, Geetha, TATOOLES, Antone, BENZ, Edward J, KAMP, Timothy J, DUDLEY, Samuel C, HUANG, Shu-Ching, ANYU ZHOU, JIANHUA ZHANG, HERMAN, Amanda M, GHASSEMZADEH, Sassan, JEONG, Euy-Myoung, KASTURIRANGAN, Srinivasan, RAICU, Mihai

“…Human heart failure is associated with decreased cardiac voltage-gated Na+ channel current (encoded by SCN5A), and the changes have been implicated in the…”
Get full text

Performance evaluation of a pediatric viscous impeller pump for Fontan cavopulmonary assist by Giridharan, Guruprasad A., PhD, Koenig, Steven C., PhD, Kennington, Jeffrey, BS, Sobieski, Michael A., RN, CCP, Chen, Jun, PhD, Frankel, Steven H., PhD, Rodefeld, Mark D., MD

“…Objective The anatomic and physiologic constraints for pediatric cavopulmonary assist differ markedly from adult Fontan circulations owing to smaller vessel…”
Get full text

Feasibility Study of Pulsatile Left Ventricular Assist Device for Prolonged Ex Vivo Lung Perfusion by Schumer, Erin M., MS, MD, Zoeller, Keith A., MEng, Linsky, Paul L., MD, Monreal, Gretel, PhD, Choi, Young, BS, Giridharan, Guruprasad A., PhD, Sobieski, Michael A., CCP, RN, Slaughter, Mark S., MD, van Berkel, Victor H., MD, PhD

“…Background Ex vivo lung perfusion (EVLP) has the potential to increase the donor pool for lung transplantation by facilitating resuscitation and extended…”
Get full text

Blood Trauma Testing of CentriMag and RotaFlow Centrifugal Flow Devices: A Pilot Study by Sobieski, Michael A., Giridharan, Guruprasad A., Ising, Mickey, Koenig, Steven C., Slaughter, Mark S.

“…Mechanical circulatory assist devices that provide temporary support in heart failure patients are needed to enable recovery or provide a bridge to decision…”
Get full text

Left Ventricular Assist Device–Associated Carbon Monoxide and Iron-Enhanced Hypercoagulation: Impact of Concurrent Disease by Nielsen, Vance G, Sobieski, Michael A, Slaughter, Mark S

“…Left ventricular assist device (LVAD) therapy is associated with thrombophilia despite anticoagulation. Of interest, LVAD patients have increased…”
Get full text

Evaluation of new Forcefield technology: Reducing platelet adhesion and cell coverage of pyrolytic carbon surfaces by Slaughter, Mark S., MD, Pederson, Brian, BS, Graham, Joel D., MS, Sobieski, Michael A., RN, CCP, Koenig, Steven C., PhD

“…Introduction Platelet adhesion and activation are a significant source of clinical complications. Preventing foreign surface–platelet interaction may improve…”
Get full text

Reducing the Effects of the Systemic Inflammatory Response to Cardiopulmonary Bypass: Can Single Dose Steroids Blunt Systemic Inflammatory Response Syndrome? by Sobieski, Michael A, Graham, Joel D, Pappas, Patroklos S, Tatooles, Antone J, Slaughter, Mark S

“…The use of cardiopulmonary bypass (CPB) is associated with the development of a significant systemic inflammatory response syndrome (SIRS) which can affect…”
Get full text

HeartWare miniature axial-flow ventricular assist device: design and initial feasibility test by Slaughter, Mark S, Sobieski, 2nd, Michael A, Tamez, Daniel, Horrell, Timothy, Graham, Joel, Pappas, Patroklos S, Tatooles, Antone J, LaRose, Jeffrey

“…Pulsatile ventricular assist devices have successfully provided circulatory support for many patients throughout the past quarter century; however, persistent…”
Get full text

Platelet activation in heart failure patients supported by the HeartMate II ventricular assist device by SLAUGHTER, Mark S, SOBIESKI, Michael A, GRAHAM, Joel D, PAPPAS, Patroklos S, TATOOLES, Antone J, KOENIG, Steven C

“…Thromboembolic events have been observed in heart failure (HF) patients supported by long-term mechanical circulatory support (MCS) devices. It has been…”
Get full text

Shear stress and blood trauma under constant and pulse-modulated speed CF-VAD operations: CFD analysis of the HVAD by Chen, Zengsheng, Jena, Sofen K., Giridharan, Guruprasad A., Sobieski, Michael A., Koenig, Steven C., Slaughter, Mark S., Griffith, Bartley P., Wu, Zhongjun J.

“…Modulation of pump speed has been proposed and implemented clinically to improve vascular pulsatility in continuous flow ventricular assist device patient. The…”
Get full text

Feasibility of Pump Speed Modulation for Restoring Vascular Pulsatility with Rotary Blood Pumps by Ising, Mickey S, Sobieski, Michael A, Slaughter, Mark S, Koenig, Steven C, Giridharan, Guruprasad A

“…Continuous flow (CF) left ventricular assist devices (LVAD) diminish vascular pressure pulsatility, which may be associated with clinically reported adverse…”
Get full text

Mechanistic insight of platelet apoptosis leading to non-surgical bleeding among heart failure patients supported by continuous-flow left ventricular assist devices by Mondal, Nandan K., Li, Tieluo, Chen, Zengsheng, Chen, Hegang H., Sorensen, Erik N., Pham, Si M., Sobieski, Michael A., Koenig, Steven C., Slaughter, Mark S., Griffith, Bartley P., Wu, Zhongjun J.

“…Non-surgical bleeding (NSB) is the most common clinical complication in heart failure (HF) patients supported by continuous-flow left ventricular assist…”
Get full text

Continuous-Flow Left Ventricular Assist Device Support Improves Myocardial Supply:Demand in Chronic Heart Failure by Soucy, Kevin G., Bartoli, Carlo R., Phillips, Dustin, Giridharan, Guruprasad A., Sobieski, Michael A., Wead, William B., Dowling, Robert D., Wu, Zhongjun J., Prabhu, Sumanth D., Slaughter, Mark S., Koenig, Steven C.

“…Continuous-flow left ventricular assist devices (CF LVADs) are rotary blood pumps that improve mean blood flow, but with potential limitations of…”
Get full text

Utilization of Acoustic Signatures to Identify HeartMate XVE Device End-of-Life by Slaughter, Mark S., MD, Feldman, Chad M., MD, Sobieski, Michael A., CCP, Silver, Marc A., MD, Martin, Michele M., RN, Kurien, Sudha, RN, Coyle, Laura A., RN, Pederson, Brian, BS

“…Background As outcomes for destination therapy continue to improve, many patients are requiring left ventricular assist device (LVAD) exchange due to…”
Get full text

Cavopulmonary Assist for the Failing Fontan Circulation: Impact of Ventricular Function on Mechanical Support Strategy by Giridharan, Guruprasad A, Ising, Mickey, Sobieski, Michael A, Koenig, Steven C, Chen, Jun, Frankel, Steven, Rodefeld, Mark D

“…Mechanical circulatory support—either ventricular assist device (VAD, left-sided systemic support) or cavopulmonary assist device (CPAD, right-sided…”
Get full text

Rotary Pumps and Diminished Pulsatility: Do We Need a Pulse? by Soucy, Kevin G, Koenig, Steven C, Giridharan, Guruprasad A, Sobieski, Michael A, Slaughter, Mark S

“…Ventricular assist devices (VADs) have been successfully used as a bridge to heart transplant and destination therapy (DT) for congestive heart failure (HF)…”
Get full text

Miniaturization of Mechanical Circulatory Support Systems by Giridharan, Guruprasad A., Lee, Thomas J., Ising, Mickey, Sobieski, Michael A., Koenig, Steven C., Gray, Laman A., Slaughter, Mark S.

“…Heart failure (HF) is increasing worldwide and represents a major burden in terms of health care resources and costs. Despite advances in medical care,…”
Get full text

Large Animal Models for Left Ventricular Assist Device Research and Development by Monreal, Gretel, Sherwood, Leslie C, Sobieski, Michael A, Giridharan, Guruprasad A, Slaughter, Mark S, Koenig, Steven C

“…In vivo preclinical testing of left ventricular assist devices (LVADs) warrants a large animal model that faithfully simulates human etiology. Although LVAD…”
Get full text