Search Results - "Sobel, Eric S."

First assessment of three-dimensional quantitative photoacoustic tomography for in vivo detection of osteoarthritis in the finger joints by Sun, Yao, Sobel, Eric S., Jiang, Huabei

“…Purpose: The purpose of this pilot clinical study is to assess three-dimensional (3-D) quantitative photoacoustic tomography (qPAT) for in vivo detection of…”
Get full text

Autoimmune inner ear disease: A systematic review of management by Breslin, Nathaniel K., Varadarajan, Varun V., Sobel, Eric S., Haberman, Rex S.

“…Objectives The study systematically reviewed the existing literature on the management of autoimmune inner ear disease (AIED). Study Design Systematic review…”
Get full text

Tomographic x-ray-guided three-dimensional diffuse optical tomography of osteoarthritis in the finger joints by Yuan, Zhen, Zhang, Qizhi, Sobel, Eric S, Jiang, Huabei

“…We describe a multimodality imaging approach that combines x-ray tomosynthesis with near-infrared diffuse optical tomography (DOT) for high-resolution imaging…”
Get more information

Citrulline Dependence of Anti-Cyclic Citrullinated Peptide Antibodies in Systemic Lupus Erythematosus as a Marker of Deforming/Erosive Arthritis by KAKUMANU, Prasanthi, SOBEL, Eric S, SATOH, Minoru, NARAIN, Sonali, YI LI, AKAOGI, Jun, YAMASAKI, Yoshioki, SEGAL, Mark S, HAHN, Paulette C, CHAN, Edward K. L, REEVES, Westley H

“…Objective. Anti-cyclic citrullinated peptide (CCP) antibodies are a serological marker for rheumatoid arthritis (RA); up to 10%–15% of patients with systemic…”
Get full text

Pathogenic role of B cells in the development of diffuse alveolar hemorrhage induced by pristane by Barker, Tolga T, Lee, Pui Y, Kelly-Scumpia, Kindra M, Weinstein, Jason S, Nacionales, Dina C, Kumagai, Yutaro, Akira, Shizuo, Croker, Byron P, Sobel, Eric S, Reeves, Westley H, Satoh, Minoru

“…Diffuse alveolar hemorrhage is an uncommon, yet often fatal, complication of systemic lupus erythematosus (SLE). Advances in the treatment of alveolar…”
Get full text

Normalization of CD4+ T cell metabolism reverses lupus by Yin, Yiming, Choi, Seung-Chul, Xu, Zhiwei, Perry, Daniel J, Seay, Howard, Croker, Byron P, Sobel, Eric S, Brusko, Todd M, Morel, Laurence

“…Systemic lupus erythematosus (SLE) is an autoimmune disease in which autoreactive CD4(+) T cells play an essential role. CD4(+) T cells rely on glycolysis for…”
Get more information

Gender and ethnicity differences in the prevalence of scleroderma-related autoantibodies by Krzyszczak, Malgorzata E., Li, Yi, Ross, Steven J., Ceribelli, Angela, Chan, Edward K. L., Bubb, Michael R., Sobel, Eric S., Reeves, Westley H., Satoh, Minoru

“…Autoantibodies to topoisomerase I (topo I), RNA polymerase III (RNAPIII), centromere, U3RNP/fibrillarin, Th, PM-Scl, and U1RNP found in scleroderma (SSc) are…”
Get full text

Metformin Inhibits the Type 1 IFN Response in Human CD4 + T Cells by Titov, Anton A, Baker, Henry V, Brusko, Todd M, Sobel, Eric S, Morel, Laurence

“…In systemic lupus erythematosus, defective clearance of apoptotic debris and activation of innate cells result in a chronically activated type 1 IFN response,…”
Get full text

Induction of Apoptosis by the Hydrocarbon Oil Pristane: Implications for Pristane-Induced Lupus by Calvani, Nicola, Caricchio, Roberto, Tucci, Marco, Sobel, Eric S, Silvestris, Franco, Tartaglia, Paola, Richards, Hanno B

“…Intraperitoneal injection of the hydrocarbon oil pristane into normal mice leads to a lupus-like autoimmune syndrome. Although advances in defining the roles…”
Get full text

Systemic Overexpression of IL-10 Induces CD4+CD25+ Cell Populations In Vivo and Ameliorates Type 1 Diabetes in Nonobese Diabetic Mice in a Dose-Dependent Fashion by Goudy, Kevin S, Burkhardt, Brant R, Wasserfall, Clive, Song, Sihong, Campbell-Thompson, Martha L, Brusko, Todd, Powers, Matthew A, Clare-Salzler, Michael J, Sobel, Eric S, Ellis, Tamir M, Flotte, Terence R, Atkinson, Mark A

“…Early systemic treatment of nonobese diabetic mice with high doses of recombinant adeno-associated virus (rAAV) vector expressing murine IL-10 prevents type 1…”
Get full text

S3025 Hepatic Sarcoidosis Presenting as Decompensated Liver Cirrhosis by Paudel, Bishal, Edwards, Emily S., Sobel, Eric S., Sheer, Amy J.

Get full text

Immunophenotyping reveals distinct subgroups of lupus patients based on their activated T cell subsets by Perry, Daniel J., Titov, Anton A., Sobel, Eric S., Brusko, Todd M., Morel, Laurence

“…This study performed an integrated analysis of the cellular and transcriptional differences in peripheral immune cells between patients with Systemic Lupus…”
Get full text

Quantitative two-dimensional photoacoustic tomography of osteoarthritis in the finger joints by Xiao, Jiaying, Yao, Lei, Sun, Yao, Sobel, Eric S, He, Jishan, Jiang, Huabei

“…We present for the first time in vivo experimental evidence that quantitative photoacoustic tomography (qPAT) has the potential to detect osteoarthritis (OA)…”
Get full text

Type I Interferon Modulates Monocyte Recruitment and Maturation in Chronic Inflammation by Lee, Pui Y, Li, Yi, Kumagai, Yutaro, Xu, Yuan, Weinstein, Jason S, Kellner, Erinn S, Nacionales, Dina C, Butfiloski, Edward J, van Rooijen, Nico, Akira, Shizuo, Sobel, Eric S, Satoh, Minoru, Reeves, Westley H

“…Chronic inflammation is characterized by continuous recruitment and activation of immune cells such as monocytes in response to a persistent stimulus…”
Get full text

Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression by Choi, Seung-Chul, Park, Yuk Pheel, Roach, Tracoyia, Jimenez, Damian, Fisher, Amanda, Zadeh, Mojgan, Ma, Longhuan, Sobel, Eric S, Ge, Yong, Mohamadzadeh, Mansour, Morel, Laurence

“…The maintenance of regulatory T (T ) cells critically prevents autoimmunity. Pre-B cell leukemia transcription factor 1 ( ) variants are associated with lupus…”
Get full text

IL-1α modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oil by Lee, Pui Y, Kumagai, Yutaro, Xu, Yuan, Li, Yi, Barker, Tolga, Liu, Chao, Sobel, Eric S, Takeuchi, Osamu, Akira, Shizuo, Satoh, Minoru, Reeves, Westley H

“…Exposure to naturally occurring hydrocarbon oils is associated with the development of chronic inflammation and a wide spectrum of pathological findings in…”
Get full text

Reduced levels of CCL2 and CXCL10 in systemic lupus erythematosus patients under treatment with prednisone, mycophenolate mofetil, or hydroxychloroquine, except in a high STAT1 subset by Dominguez-Gutierrez, Paul R, Ceribelli, Angela, Satoh, Minoru, Sobel, Eric S, Reeves, Westley H, Chan, Edward K L

“…Our recent data showed that signal transducers and activators of transcription 1 (STAT1), adenosine deaminase acting on RNA (ADAR), C-C motif chemokine ligand…”
Get full text

Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus by Dominguez-Gutierrez, Paul R, Ceribelli, Angela, Satoh, Minoru, Sobel, Eric S, Reeves, Westley H, Chan, Edward K L

“…The present study examines the levels of recently reported biomarkers, adenosine deaminase acting on RNA (ADAR), C-C motif chemokine ligand 2 (CCL2), C-X-C…”
Get full text

Defective B-cell response to T-dependent immunization in lupus-prone mice by Niu, Haitao, Sobel, Eric S, Morel, Laurence

“…Lupus anti-nuclear Ab show the characteristics of Ag-driven T-cell-dependent (TD) humoral responses. If autoAg elicit the same response as exogenous Ag, lupus…”
Get full text

Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus by Li, Yi, Lee, Pui Y, Kellner, Erinn S, Paulus, Matthew, Switanek, Juliana, Xu, Yuan, Zhuang, Haoyang, Sobel, Eric S, Segal, Mark S, Satoh, Minoru, Reeves, Westley H

“…Introduction More than half of systemic lupus erythematosus (SLE) patients show evidence of excess type I Interferon (IFN-I) production, a phenotype associated…”
Get full text