Search Results - "Sobel, Andre"

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain by Knossow, Marcel, Ravelli, Raimond B.G, Gigant, Benoît, Curmi, Patrick A, Jourdain, Isabelle, Lachkar, Sylvie, Sobel, André

“…Microtubules are cytoskeletal polymers of tubulin involved in many cellular functions. Their dynamic instability is controlled by numerous compounds and…”
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Specific Serine-Proline Phosphorylation and Glycogen Synthase Kinase 3β-directed Subcellular Targeting of Stathmin 3/Sclip in Neurons by Devaux, Sara, Poulain, Fabienne E., Devignot, Véronique, Lachkar, Sylvie, Irinopoulou, Theano, Sobel, André

“…During nervous system development, neuronal growth, migration, and functional morphogenesis rely on the appropriate control of the subcellular cytoskeleton…”
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Neuronal stathmins: a family of phosphoproteins cooperating for neuronal development, plasticity and regeneration by Chauvin, Stéphanie, Sobel, André

“…Nervous system development, plasticity and regeneration require numerous, coordinated and finely tuned subcellular mechanisms. Phosphoproteins of the stathmin…”
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Drosophila Stathmins Bind Tubulin Heterodimers with High and Variable Stoichiometries by Lachkar, Sylvie, Lebois, Marion, Steinmetz, Michel O., Guichet, Antoine, Lal, Neha, Curmi, Patrick A., Sobel, André, Ozon, Sylvie

“…In vertebrates, stathmins form a family of proteins possessing two tubulin binding repeats (TBRs), which each binds one soluble tubulin heterodimer. The…”
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Stathmin: a relay phosphoprotein for multiple signal transduction? by Sobel, A

“…Stathmin is a ubiquitous, phylogenetically conserved protein present in the cytoplasm of cells in a variety of unphosphorylated and phosphorylated forms. Its…”
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The microtubule network and neuronal morphogenesis: Dynamic and coordinated orchestration through multiple players by Poulain, Fabienne E., Sobel, André

“…Nervous system function and plasticity rely on the complex architecture of neuronal networks elaborated during development, when neurons acquire their specific…”
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Phosphorylation of the tubulin‐binding protein, stathmin, by Cdk5 and MAP kinases in the brain by Hayashi, Kanehiro, Pan, Yong, Shu, Hongjun, Ohshima, Toshio, Kansy, Janice W., White, Charles L., Tamminga, Carol A., Sobel, André, Curmi, Patrick A., Mikoshiba, Katsuhiko, Bibb, James A.

“…Regulation of cytoskeletal dynamics is essential to neuronal plasticity during development and adulthood. Dysregulation of these mechanisms may contribute to…”
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Drosophila stathmin: a microtubule-destabilizing factor involved in nervous system formation by Ozon, Sylvie, Guichet, Antoine, Gavet, Olivier, Roth, Siegfried, Sobel, André

“…Stathmin is a ubiquitous regulatory phosphoprotein, the generic element of a family of neural phosphoproteins in vertebrates that possess the capacity to bind…”
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Expression of Stathmin, a Developmentally Controlled Cytoskeleton-Regulating Molecule, in Demyelinating Disorders by Liu, Aixiao, Stadelmann, Christine, Moscarello, Mario, Bruck, Wolfgang, Sobel, Andre, Mastronardi, Fabrizio G, Casaccia-Bonnefil, Patrizia

“…Understanding the biological relevance of reexpression of developmental molecules in pathological conditions is crucial for the development of new therapies…”
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Stathmin and its Phosphoprotein Family: General Properties, Biochemical and Functional Interaction with Tubulin by Curmi, Patrick A., Gavet, Olivier, Charbaut, Elodie, Ozon, Sylvie, Lachkar-Colmerauer, Sylvie, Manceau, Valerie, Siavoshian, Samila, Maucuer, Alexandre, Sobel, Andre

“…Stathmin, also referred to as Op18, is a ubiquitous cytosolic phosphoprotein, proposed to be a small regulatory protein and a relay integrating diverse…”
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Structural basis for the regulation of tubulin by vinblastine by Knossow, Marcel, Gigant, Benoît, Wang, Chunguang, Ravelli, Raimond B. G, Roussi, Fanny, Steinmetz, Michel O, Curmi, Patrick A, Sobel, André

“…Vinblastine is one of several tubulin-targeting Vinca alkaloids that have been responsible for many chemotherapeutic successes since their introduction in the…”
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Probing Interactions of Tubulin with Small Molecules, Peptides, and Protein Fragments by Solution Nuclear Magnetic Resonance by Clément, Marie-Jeanne, Savarin, Philippe, Adjadj, Elisabeth, Sobel, André, Toma, Flavio, Curmi, Patrick A.

“…The description of the molecular mechanisms of interaction between tubulin or microtubules and partners at atomic scale is expected to have critical impacts on…”
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The microtubule destabilizing protein stathmin controls the transition from dividing neuronal precursors to postmitotic neurons during adult hippocampal neurogenesis by Boekhoorn, Karin, Dis, Vera, Goedknegt, Erika, Sobel, André, Lucassen, Paul J., Hoogenraad, Casper C.

“…ABSTRACT The hippocampus is one of the two areas in the mammalian brain where adult neurogenesis occurs. Adult neurogenesis is well known to be involved in…”
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Stathmin/Op18 phosphorylation is regulated by microtubule assembly by Küntziger, T, Gavet, O, Manceau, V, Sobel, A, Bornens, M

“…Stathmin/Op 18 is a microtubule (MT) dynamics-regulating protein that has been shown to have both catastrophe-promoting and tubulin-sequestering activities…”
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Enhanced Expression of Uterine Stathmin during the Process of Implantation and Decidualization in Rats by Tamura, Kazuhiro, Hara, Takahiko, Yoshie, Mikihiro, Irie, Shinya, Sobel, Andre, Kogo, Hiroshi

“…We used the library subtraction technique to identify genes specifically expressed in the rat uterus during early pregnancy. One such gene was that for…”
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Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases by Levy, Aurore D, Devignot, Véronique, Fukata, Yuko, Fukata, Masaki, Sobel, André, Chauvin, Stéphanie

“…Protein palmitoylation is a reversible lipid modification that plays critical roles in protein sorting and targeting to specific cellular compartments. The…”
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Stathmin Interaction with a Putative Kinase and Coiled-Coil-Forming Protein Domains by Maucuer, Alexandre, Camonis, Jacques H., Sobel, André

“…Stathmin is a ubiquitous, cytosolic 19-kDa protein, which is phosphorylated on up to four sites in response to many regulatory signals within cells. Its…”
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Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes by Honnorat, Jérôme, Byk, Tamara, Kusters, Inca, Aguera, Michèle, Ricard, Damien, Rogemond, Véronique, Quach, Tam, Aunis, Dominique, Sobel, André, Mattei, Marie-Geneviève, Kolattukudy, Pappachan, Belin, Marie-Françoise, Antoine, Jean Christophe

“…Anti‐CV2 autoantibodies have recently been discovered in patients with paraneoplastic neurological diseases (PND). These disorders are associated with neuronal…”
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The PN2-3 Domain of Centrosomal P4.1-associated Protein Implements a Novel Mechanism for Tubulin Sequestration by Cormier, Anthony, Clément, Marie-Jeanne, Knossow, Marcel, Lachkar, Sylvie, Savarin, Philippe, Toma, Flavio, Sobel, André, Gigant, Benoît, Curmi, Patrick A.

“…Microtubules are cytoskeletal components involved in multiple cell functions such as mitosis, motility, or intracellular traffic. In vivo, these polymers made…”
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The “SCG10-LIke Protein” SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10 by Poulain, Fabienne E., Sobel, André

“…Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal…”
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