Search Results - "Sobala, Łukasz F."

Evolution and phylogenetic distribution of endo-α-mannosidase by Sobala, Łukasz F

“…Abstract While glycans underlie many biological processes, such as protein folding, cell adhesion, and cell–cell recognition, deep evolution of glycosylation…”
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Sialic Acids as Receptors for Pathogens by Burzyńska, Patrycja, Sobala, Łukasz F, Mikołajczyk, Krzysztof, Jodłowska, Marlena, Jaśkiewicz, Ewa

“…Carbohydrates have long been known to mediate intracellular interactions, whether within one organism or between different organisms. Sialic acids (Sias) are…”
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Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target by Sobala, Łukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S., Williams, Spencer J., Davies, Gideon J.

“…Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are…”
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Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut by Hemsworth, Glyn R., Thompson, Andrew J., Stepper, Judith, Sobala, Łukasz F., Coyle, Travis, Larsbrink, Johan, Spadiut, Oliver, Goddard-Borger, Ethan D., Stubbs, Keith A., Brumer, Harry, Davies, Gideon J.

“…The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members…”
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The Gene Expression Program for the Formation of Wing Cuticle in Drosophila by Sobala, Lukasz F, Adler, Paul N

“…The cuticular exoskeleton of insects and other arthropods is a remarkably versatile material with a complex multilayer structure. We made use of the ability to…”
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ChtVis-Tomato, a genetic reporter for in vivo visualization of chitin deposition in Drosophila by Sobala, Lukasz F, Wang, Ying, Adler, Paul N

“…Chitin is a polymer of N-acetylglucosamine that is abundant and widely found in the biological world. It is an important constituent of the cuticular…”
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dusky-like is required to maintain the integrity and planar cell polarity of hairs during the development of the Drosophila wing by Adler, Paul N., Sobala, Lukasz F., Thom, DeSean, Nagaraj, Ranganayaki

“…The cuticular hairs and sensory bristles that decorate the adult Drosophila epidermis and the denticles found on the embryo have been used in studies on planar…”
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Spiro‐epoxyglycosides as Activity‐Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase by Schröder, Sybrin P., Kallemeijn, Wouter W., Debets, Marjoke F., Hansen, Thomas, Sobala, Lukasz F., Hakki, Zalihe, Williams, Spencer J., Beenakker, Thomas J. M., Aerts, Johannes M. F. G., van der Marel, Gijsbert A., Codée, Jeroen D. C., Davies, Gideon J., Overkleeft, Herman S.

“…N‐Glycans direct protein function, stability, folding and targeting, and influence immunogenicity. While most glycosidases that process N‐glycans cleave a…”
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An Epoxide Intermediate in Glycosidase Catalysis by Sobala, Lukasz F, Speciale, Gaetano, Zhu, Sha, Raich, Lluı́s, Sannikova, Natalia, Thompson, Andrew J, Hakki, Zalihe, Lu, Dan, Shamsi Kazem Abadi, Saeideh, Lewis, Andrew R, Rojas-Cervellera, Vı́ctor, Bernardo-Seisdedos, Ganeko, Zhang, Yongmin, Millet, Oscar, Jiménez-Barbero, Jesús, Bennet, Andrew J, Sollogoub, Matthieu, Rovira, Carme, Davies, Gideon J, Williams, Spencer J

“…Retaining glycoside hydrolases cleave their substrates through stereochemical retention at the anomeric position. Typically, this involves two-step mechanisms…”
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LukProt: A Database of Eukaryotic Predicted Proteins Designed for Investigations of Animal Origins by Sobala, Łukasz F

“…Abstract The origins and early evolution of animals are subjects with many outstanding questions. One problem faced by researchers trying to answer them is the…”
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From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase by Lu, Dan, Zhu, Sha, Sobala, Lukasz F, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhang, Yongmin, Jiménez-Barbero, Jesus, Davies, Gideon J, Sollogoub, Matthieu

“…Understanding the enzyme reaction mechanism can lead to the design of enzyme inhibitors. A Claisen rearrangement was used to allow conversion of an…”
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A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites by Sernee, M. Fleur, Ralton, Julie E., Nero, Tracy L., Sobala, Lukasz F., Kloehn, Joachim, Vieira-Lara, Marcel A., Cobbold, Simon A., Stanton, Lauren, Pires, Douglas E.V., Hanssen, Eric, Males, Alexandra, Ward, Tom, Bastidas, Laurence M., van der Peet, Phillip L., Parker, Michael W., Ascher, David B., Williams, Spencer J., Davies, Gideon J., McConville, Malcolm J.

“…Parasitic protists belonging to the genus Leishmania synthesize the non-canonical carbohydrate reserve, mannogen, which is composed of β-1,2-mannan…”
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Correction: ChtVis-Tomato, a genetic reporter for in vivo visualization of chitin deposition in Drosophila by Sobala, Lukasz F, Wang, Ying, Adler, Paul N

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Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase by Petricevic, Marija, Sobala, Lukasz F, Fernandes, Pearl Z, Raich, Lluís, Thompson, Andrew J, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J, Williams, Spencer J

“…Inhibitor design incorporating features of the reaction coordinate and transition-state structure has emerged as a powerful approach for the development of…”
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Structure of a Talaromyces pinophilus GH62 arabinofuranosidase in complex with AraDNJ at 1.25 Å resolution by Moroz, Olga V., Sobala, Lukasz F., Blagova, Elena, Coyle, Travis, Peng, Wei, Mørkeberg Krogh, Kristian B. R., Stubbs, Keith A., Wilson, Keith S., Davies, Gideon J.

“…The enzymatic hydrolysis of complex plant biomass is a major societal goal of the 21st century in order to deliver renewable energy from nonpetroleum and…”
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LukProt - an animal evolution-centric eukaryotic protein database by Sobala, Łukasz F.

“…LukProt is the EukProt database with additional species added, mostly the undersampled animal and some holozoan taxa. Please report any problems or suggestions…”
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Contribution of Shape and Charge to the Inhibition of a Family GH99 \textitendo -α-1,2-Mannanase by Petricevic, Marija, Sobala, Lukasz F., Fernandes, Pearl Z., Raich, Lluís, Thompson, Andrew J., Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J., Williams, Spencer J.

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