Search Results - "Soares, Maria Vieira D."

Integration of apoptosis and telomere erosion in virus-specific CD8+T cells from blood and tonsils during primary infection by Soares, Maria Vieira D., Plunkett, Fiona J., Verbeke, Caroline S., Cook, Joanne E., Faint, Jeff M., Belaramani, Lavina L., Fletcher, Jean M., Hammerschmitt, Nicholas, Rustin, Malcolm, Bergler, Wolfgang, Beverley, Peter C.L., Salmon, Mike, Akbar, Arne N.

“…Human-virus–specific CD8+T cells that are found during primary infection have been studied almost exclusively in the peripheral blood, and it is unclear…”
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IL-7 sustains CD31 expression in human naive CD4+ T cells and preferentially expands the CD31+ subset in a PI3K-dependent manner by Azevedo, Rita I., Soares, Maria Vieira D., Barata, João T., Tendeiro, Rita, Serra-Caetano, Ana, Victorino, Rui M.M., Sousa, Ana E.

“…The CD31+ subset of human naive CD4+ T cells is thought to contain the population of cells that have recently emigrated from the thymus, while their CD31−…”
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Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo by Reed, John R, Vukmanovic-Stejic, Milica, Fletcher, Jean M, Soares, Maria Vieira D, Cook, Joanne E, Orteu, Catherine H, Jackson, Sarah E, Birch, Katie E, Foster, Graham R, Salmon, Mike, Beverley, Peter C L, Rustin, Malcolm H A, Akbar, Arne N

“…The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is…”
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Epstein-Barr virus–specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential by Dunne, Padraic J., Faint, Jeffery M., Gudgeon, Nancy H., Fletcher, Jean M., Plunkett, Fiona J., Soares, Maria Vieira D., Hislop, Andrew D., Annels, Nicola E., Rickinson, Alan B., Salmon, Mike, Akbar, Arne N.

“…During acute infection, latent and lytic Epstein-Barr virus (EBV) epitope-specific CD8+ T cells have a CD45RO+CD45RA− phenotype. However, after resolution of…”
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The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection by Plunkett, Fiona J., Soares, Maria Vieira D., Annels, Nicola, Hislop, Andrew, Ivory, Kamal, Lowdell, Mark, Salmon, Mike, Rickinson, Alan, Akbar, Arne N.

“…Acute infectious mononucleosis (AIM) induced by Epstein-Barr virus (EBV) infection is characterized by extensive expansion of antigen-specific CD8+ T cells…”
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Quiescence and functional reprogramming of Epstein-Barr virus (EBV)–specific CD8+ T cells during persistent infection by Dunne, Pádraic J., Belaramani, Lavina, Fletcher, Jean M., de Mattos, Silvia Fernandez, Lawrenz, Maria, Soares, Maria Vieira D., Rustin, Malcolm H.A., Lam, Eric W.-F., Salmon, Mike, Akbar, Arne N.

“…After acute infection Epstein-Barr virus (EBV)–specific memory CD8+ T cells exit cell cycle, and a proportion of these antigen-experienced cells reexpress…”
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Virus-Induced CD8+ T Cell Clonal Expansion Is Associated with Telomerase Up-Regulation and Telomere Length Preservation: A Mechanism for Rescue from Replicative Senescence by Maini, Mala K, Soares, Maria Vieira D, Zilch, Christian F, Akbar, Arne N, Beverley, Peter C. L

“…In acute infectious mononucleosis (AIM), very large clones of Ag-specific CD8+ effector T cells are generated. Many clones persist as memory cells, although…”
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Differential regulation of CD8 + T cell senescence in mice and men by Akbar, Arne N, Soares, Maria Vieira D, Plunkett, Fiona J, Salmon, Mike

“…The cytotoxic CD8 + T cell population expands considerably during acute immune infection with virus. Most of these cells are removed by apoptosis at the end of…”
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IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire by Vieira, Maria, Soares, D, Borthwick, Nicola J, Maini, Mala K, Janossy, George, Salmon, Mike, Akbar, Arne N

“…We have investigated the regulation of adult and cord blood CD45RA+ T cell proliferation and apoptosis to identify factors that may control the naive T cell…”
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Differential regulation of CD8+ T cell senescence in mice and men by AKBAR, Arne N, SOARES, Maria Vieira D, PLUNKETT, Fiona J, SALMON, Mike

“…The cytotoxic CD8+ T cell population expands considerably during acute immune infection with virus. Most of these cells are removed by apoptosis at the end of…”
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