Search Results - "Soares, Hugo R."

Pseudotyping retrovirus like particles vaccine candidates with Hepatitis C virus envelope protein E2 requires the cellular expression of CD81 by Soares, Hugo R., Castro, Rute, Tomás, Hélio A., Carrondo, Manuel J. T., Alves, Paula M., Coroadinha, Ana S.

“…Hepatitis C virus (HCV) infects 3% of world population being responsible for nearly half a million deaths annually urging the need for a prophylactic vaccine…”
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Delivery of an anti‐transthyretin Nanobody to the brain through intranasal administration reveals transthyretin expression and secretion by motor neurons by Gomes, João R., Cabrito, Inês, Soares, Hugo R., Costelha, Susete, Teixeira, Anabela, Wittelsberger, Angela, Stortelers, Catelijne, Vanlandschoot, Peter, Saraiva, Maria J.

“…Transthyretin (TTR) is a transport protein of retinol and thyroxine in serum and CSF, which is mainly secreted by liver and choroid plexus, and in smaller…”
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New Low-Toxicity Cholinium-Based Ionic Liquids with Perfluoroalkanoate Anions for Aqueous Biphasic System Implementation by Patinha, David J. S, Tomé, Liliana C, Florindo, Catarina, Soares, Hugo R, Coroadinha, Ana S, Marrucho, Isabel M

“…This work explores the widening of properties of cholinium-based ionic liquids (ILs) through their combination with perfluoroalkanoate anions so that higher…”
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Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology by Rodrigues, Ana F., Soares, Hugo R., Guerreiro, Miguel R., Alves, Paula M., Coroadinha, Ana S.

“…Vaccination is one of the most effective interventions in global health. The worldwide vaccination programs significantly reduced the number of deaths caused…”
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Enhancing Hepatitis C virus pseudoparticles infectivity through p7NS2 cellular expression by Soares, Hugo R., Ferreira-Fernandes, Marina, Almeida, Ana I., Marchel, Mateusz, Alves, Paula M., Coroadinha, Ana S.

“…[Display omitted] •Establishment of a versatile cell line producing high titers of Hepatitis C Virus pseudoparticles.•Cellular co-expression of HCV p7NS2 ORF…”
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Flexible pseudotyping of retrovirus using recombinase-mediated cassette exchange by Soares, Hugo R., Almeida, Ana I., Tomás, Hélio A., Alves, Paula M., Coroadinha, Ana S.

“…Objective Develop an engineered cell line containing two flexible gene expression systems enabling the continuous production of tailor-made recombinant…”
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Semliki Forest Virus replicon particles production in serum-free medium BHK-21 cell cultures and their use to express different proteins by Suárez-Patiño, Sandra Fernanda, Bernardino, Thaissa Consoni, Núñez, Eutimio Gustavo Fernández, Astray, Renato Mancini, Pereira, Carlos Augusto, Soares, Hugo R., Coroadinha, Ana S., Jorge, Soraia Attie Calil

“…The production of biopharmaceuticals as vaccines in serum-free media results in reduced risk of contamination and simpler downstream processing. The production…”
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High‐throughput screening of aqueous biphasic systems with ionic liquids as additives for extraction and purification of enveloped virus‐like particles by Marchel, Mateusz, Soares, Hugo R., Vormittag, Philipp, Hubbuch, Jürgen, Coroadinha, Ana S., Marrucho, Isabel M.

“…Due to their unique properties, virus‐like particles (VLPs) have been portrayed as a promising high‐value biopharmaceutical in VLP‐based vaccination and cancer…”
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