Search Results - "Soares, Carlos R.J"

Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice by Furigo, Isadora C, Suzuki, Miriam F, Oliveira, João E, Ramos-Lobo, Angela M, Teixeira, Pryscila D S, Pedroso, João A, de Alencar, Amanda, Zampieri, Thais T, Buonfiglio, Daniella C, Quaresma, Paula G F, Prada, Patricia O, Bartolini, Paolo, Soares, Carlos R J, Donato, Jr, Jose

“…Previous studies have shown that bromocriptine mesylate (Bromo) lowers blood glucose levels in adults with type 2 diabetes mellitus; however, the mechanism of…”
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Poly(3-hydroxi-butyrate-co-3-hydroxy-valerate) (PHB-HV) microparticles loaded with holmium acetylacetonate as potential contrast agents for magnetic resonance images by de Azevedo, Mariangela de Burgos M, Melo, Vitor Hs, Soares, Carlos Rj, Gamarra, Lionel F, Barros, Caio Hn, Tasic, Ljubica

“…Biodegradable polymers that contain radioactive isotopes such as Holmium 166 have potential applications as beta particle emitters in tumor tissues. Also,…”
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N-glycoprofiling analysis in a simple glycoprotein model: A comparison between recombinant and pituitary glycosylated human prolactin by Capone, Marcos V.N., Suzuki, Miriam F., Oliveira, João E., Damiani, Renata, Soares, Carlos R.J., Bartolini, Paolo

“…•Cyclohexemide greatly increased glycosylation site occupancy in CHO-derived G-hPRL.•N-glycan structures were determined in native and CHO-derived G-hPRL and…”
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High-yield purification of biosynthetic human growth hormone secreted in Escherichia coli periplasmic space by de Oliveira, João Ezequiel, Soares, Carlos R.J, Peroni, Cibele N, Gimbo, Elizabeth, Camargo, Iara M.C, Morganti, Ligia, Bellini, Maria Helena, Affonso, Regina, Arkaten, Rosangela R, Bartolini, Paolo, Ribela, Maria Teresa C.P

“…A six-step, high-yield purification procedure for the preparation of clinical grade recombinant human growth hormone (rhGH) secreted in bacterial periplasmic…”
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Distribution of growth hormone-responsive cells in the mouse brain by Furigo, Isadora C., Metzger, Martin, Teixeira, Pryscila D. S., Soares, Carlos R. J., Donato, Jose

“…Growth hormone (GH) exerts important biological effects primarily related to growth and metabolism. However, the role of GH signaling in the brain is still…”
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Biophysical properties of electrospun chitosan-grafted poly(lactic acid) nanofibrous scaffolds loaded with chondroitin sulfate and silver nanoparticles by Júnior, Alexandre F, Ribeiro, Charlene A, Leyva, Maria E, Marques, Paulo S, Soares, Carlos R J, Alencar de Queiroz, Alvaro A

“…The aim of this work was to study the biophysical properties of the chitosan-grafted poly(lactic acid) (CH-g-PLA) nanofibers loaded with silver nanoparticles…”
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Brain STAT5 signaling modulates learning and memory formation by Furigo, Isadora C., Melo, Helen M., Lyra e Silva, Natalia M., Ramos-Lobo, Angela M., Teixeira, Pryscila D. S., Buonfiglio, Daniella C., Wasinski, Frederick, Lima, Eliana R., Higuti, Eliza, Peroni, Cibele N., Bartolini, Paolo, Soares, Carlos R. J., Metzger, Martin, de Felice, Fernanda G., Donato, Jose

“…The signal transducer and activator of transcription 5 (STAT5) is a transcription factor recruited by numerous cytokines. STAT5 is important for several…”
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Determination of recombinant Interferon-α2 in E. coli periplasmic extracts by reversed-phase high-performance liquid chromatography by Dias, Paulo V.S., Arthuso, Fernanda S., Oliveira, João E., Suzuki, Miriam F., Sousa, José M., Ribela, Maria Teresa C.P., Bartolini, Paolo, Soares, Carlos R.J.

“…•A HPLC method for direct analysis of IFN-α2 in periplasmic extracts.•A HPLC method for an accurate quali- and quantitative analysis of IFN-α2.•A fast method…”
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Expression, purification and characterization of the authentic form of human growth hormone receptor antagonist G120R-hGH obtained in Escherichia coli periplasmic space by Menezes, Ana C.S.C., Suzuki, Miriam F., Oliveira, João E., Ribela, Maria T.C.P., Furigo, Isadora C., Donato, José, Bartolini, Paolo, Soares, Carlos R.J.

“…The human growth hormone receptor antagonist G120R-hGH precludes dimerization of GH and prolactin receptors and consequently JAK/STAT signaling. Some…”
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Periplasmic synthesis and purification of the human prolactin antagonist Δ1-11-G129R-hPRL by Suzuki, Miriam F., Almeida, Larissa A., Pomin, Stephanie A., Silva, Felipe D., Freire, Renan P., Oliveira, João E., Affonso, Regina, Soares, Carlos R. J., Bartolini, Paolo

“…The human prolactin antagonist Δ 1-11 -G129R-hPRL is a 21.9 kDa recombinant protein with 188 amino acids that downregulates the proliferation of a variety of…”
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Human Macroprolactin Displays Low Biological Activity via Its Homologous Receptor in a New Sensitive Bioassay by Glezer, Andrea, Soares, Carlos R. J., Vieira, José G., Giannella-Neto, Daniel, Ribela, Maria Teresa C. P., Goffin, Vincent, Bronstein, Marcello D.

“…Context: Macroprolactinemia is a frequent finding in hyperprolactinemic individuals, usually without clinical impact. Data on biological activity of…”
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Expression, purification, and characterization of authentic mouse prolactin obtained in Escherichia coli periplasmic space by Suzuki, Miriam F., Arthuso, Fernanda S., Oliveira, João E., Oliveira, Nélio A. J., Goulart, Herbert R., Capone, Marcos V. N., Ribela, Maria Teresa C. P., Bartolini, Paolo, Soares, Carlos R. J.

“…Prolactin (PRL) is a pleiotropic hormone produced by lactotroph cells of the anterior pituitary gland and is mainly related to lactation control and…”
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A Molecular Mimic of Phosphorylated Prolactin (S179D PRL) Secreted by Eukaryotic Cells Has a Conformation with an Increased Positive Surface Charge Compared to That of Unmodified Prolactin by Ueda, Eric K. M, Soares, Carlos R. J, Bartolini, Paolo, DeGuzman, Ariel, Lorenson, Mary Y, Walker, Ameae M

“…S179D prolactin (S179D PRL) is a pseudophosphorylated form of human PRL which has potent antitumor and anti-angiogenic activities in vivo. This molecule binds…”
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Improved Bioprocess with CHO-hTSH Cells on Higher Microcarrier Concentration Provides Higher Overall Biomass and Productivity for rhTSH by Ventini, Daniella C., Damiani, Renata, Sousa, Alvaro P. B., de Oliveira, João E., Peroni, Cibele N., Ribela, Maria T. C. P., Bartolini, Paolo, Tonso, Aldo, Soares, Carlos R. J., Pereira, Carlos A.

“…Since the recombinant thyroid-stimulating hormone (rhTSH) is secreted by stably transfected Chinese hamster ovary (CHO-hTSH) cells, a bioprocess consisting of…”
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Reversed-phase high-performance liquid chromatography method for the determination of prolactin in bacterial extracts and in its purified form by Soares, Carlos R.J., Camargo, Iara M.C., Morganti, Ligia, Gimbo, Elizabeth, Ezequiel de Oliveira, João, Legoux, Richard, Ferrara, Pascual, Bartolini, Paolo

“…Reversed-phase high-performance liquid chromatography methodology for the determination of human prolactin (hPRL) in bacterial periplasmic space or in purified…”
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High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy by Peroni, Cibele Nunes, Cecchi, Cláudia Regina, Damiani, Renata, Soares, Carlos R J, Ribela, Maria Teresa C P, do Rocio Arkaten, Rosângela, Bartolini, Paolo

“…A gene therapy clinical trial for treatment of growth hormone (GH) deficiency has not been reached yet, but several strategies using different gene transfer…”
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Periplasmic expression of human growth hormone via plasmid vectors containing the  PL promoter: use of HPLC for product quantification by Soares, C. R.J., Gomide, F. I.C., Ueda, E. K.M., Bartolini, P.

“…The influence of different factors acting on Escherichia coli periplasmic expression of recombinant human growth hormone (hGH) in shake flask cultures has been…”
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High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy by Peroni, Cibele N., Soares, Carlos R. J., Gimbo, Elizabeth, Morganti, Ligia, Ribela, Maria Teresa C.P., Bartolini, Paolo

“…The utilization of dicistronic mRNA expression vectors, containing the gene of interest upstream of an amplifiable marker gene, has shown success in rapidly,…”
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High-level synthesis of human prolactin in Chinese-hamster ovary cells by Soares, Carlos R. J., Morganti, Ligia, Miloux, Brigitte, Lupker, Jan H., Ferrara, Pascual, Bartolini, Paolo

“…Two eukaryotic human prolactin (hPRL) expression vectors, based on a selectable dihydrofolate reductase (dhfr) marker, were used to transfect dhfr− Chinese‐…”
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Periplasmic expression of human growth hormone via plasmid vectors containing the λPL promoter: use of HPLC for product quantification by Soares, Carlos R.J., Gomide, Fernanda I.C., Ueda, Eric K.M., Bartolini, Paolo

“…The influence of different factors acting on Escherichia coli periplasmic expression of recombinant human growth hormone (hGH) in shake flask cultures has been…”
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