Search Results - "Soares, Alexandra Martins Santos"
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Protein-Ligand Docking Simulations with AutoDock4 Focused on the Main Protease of SARS-CoV-2
Published in Current medicinal chemistry (01-01-2021)“…The main protease of SARS-CoV-2 (M ) is one of the targets identified in SARS-CoV-2, the causative agent of COVID-19. The application of X-ray diffraction…”
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In vitro anthelmintic effects of Spigelia anthelmia protein fractions against Haemonchus contortus
Published in PloS one (15-12-2017)“…Gastrointestinal nematodes are a significant concern for animal health and well-being, and anthelmintic treatment is mainly performed through the use of…”
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The Polypeptides/Proteins Exuded from Mimosa caesalpiniifolia Seeds Induce Ultrastructural and Biomechanical Modifications of the Caenorhabditis elegans Surface and Inhibit the Nematode Motility
Published in Brazilian Archives of Biology and Technology (01-01-2024)“…Abstract Natural products have been studied as potential anthelmintic drugs. This study aimed to evaluate the effects of the polypeptides/proteins exuded from…”
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In silico and In vitro Assessment of Dimeric Flavonoids (Brachydins) on Rhipicephalus microplus Glutathione S-transferase
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2024)“…, an important cattle ectoparasite, is responsible for a substantial negative impact on the economy due to productivity loss. The emergence of resistance to…”
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The potential of plant and fungal proteins in the control of gastrointestinal nematodes from animals
Published in Revista brasileira de parasitologia veterinaria (01-07-2019)“…Gastrointestinal nematode infection is an important cause of high economic losses in livestock production. Nematode control based on a synthetic chemical…”
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Effects of essential oils on native and recombinant acetylcholinesterases of Rhipicephalus microplus
Published in Revista brasileira de parasitologia veterinaria (01-01-2021)“…This study reports the action of essential oils (EO) from five plants on the activity of native and recombinant acetylcholinesterases (AChE) from Rhipicephalus…”
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Anthelmintic activity of Leucaena leucocephala protein extracts on Haemonchus contortus
Published in Revista brasileira de parasitologia veterinaria (01-10-2015)“…The objective of this study was to evaluate the effects of protein extracts obtained from the plant Leucaena leucocephala on the nematode parasite Haemonchus…”
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A cysteine protease from the latex of Ficus benjamina has in vitro anthelmintic activity against Haemonchus contortus
Published in Revista brasileira de parasitologia veterinaria (01-10-2018)“…Haemonchus contortus is a gastrointestinal nematode that is responsible for high mortality rates in ruminant herds. The resistance of nematodes to synthetic…”
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The first assessment of the stress inducible defense of Leucaena leucocephala with acaricidal potential effect against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
Published in Revista brasileira de parasitologia veterinaria (01-04-2017)“…Plants respond to wounding caused by mechanical stress or herbivory by synthesizing defense proteins. There are no studies reporting the action of induced…”
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Terpenes on Rhipicephalus (Boophilus) microplus: Acaricidal activity and acetylcholinesterase inhibition
Published in Veterinary parasitology (01-04-2020)“…•Inhibition of AChE is a well established mechanism of action of acaricides.•The action of terpenes on tick AChEs has not hardly been studied.•P-cymene,…”
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In vitro assessment of the efficacy of protein exudates from seeds against Haemonchus contortus
Published in Veterinary parasitology (01-04-2021)“…•Seed exudates could be an excellent source of bioactive protein.•Proteins from seed exudates inhibit the artificial exsheathment of H…”
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Biological properties and pharmacological potential of plant exudates
Published in Food research international (01-03-2018)“…Exudates released from plants, consist of complex mixtures of organic and inorganic molecules that have been used in traditional medicine from several years…”
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A new 2S albumin from Jatropha curcas L. seeds and assessment of its allergenic properties
Published in Peptides (New York, N.Y. : 1980) (01-12-2009)“…Significant effort has been made world-wide to boost biofuels with the expectation of a positive contribution to renewable fuel and greenhouse gas reduction…”
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Molluscicidal activity of monoterpenes and their effects on inhibition of acetylcholinesterase activity on Biomphalaria glabrata, an intermediate host of Schistosoma mansoni
Published in Acta tropica (01-11-2021)“…•Camphor and 1,8-cineole did not induce the mortality of adult B. glabrata snails.•Thymol and α-pinene are toxic to B. glabrata in concentration recommended by…”
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Inhibition of Protease and Egg Hatching of Haemonchus contortus by Soybean Seed Exudates
Published in The Journal of parasitology (26-01-2021)“…Gastrointestinal nematode infection of small ruminants causes losses in livestock production. Plant compounds show promises as alternatives to commercial…”
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Identification of a tyrosine phosphatase involved in the response to mechanical injury in leaves of Ricinus communis
Published in Protein and peptide letters (01-01-2011)“…Plants defend themselves against biotic or abiotic stress by triggering intracellular signaling pathways that regulate gene expression and responses to the…”
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A novel glutathione-S-transferase-based biosensor for pyrethroid insecticides: From inhibition study to detection
Published in Sensors and actuators reports (01-11-2022)“…•In silico studies indicated binding affinity of pyrethroid insecticides to the glutathione S-transferase-GST catalytic site.•Also, the selected pyrethroid…”
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Assessment of different Lippia sidoides genotypes regarding their acaricidal activity against Rhipicephalus (Boophilus) microplus
Published in Revista brasileira de parasitologia veterinaria (01-10-2016)“…The aim of this study was to select different genotypes of Lippia sidoides with the highest activity against larvae and engorged females of the tick…”
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An alkaloidal fraction of Annona tomentosa possesses anthelmintic activity and induces surface modifications in Haemonchus contortus
Published in Veterinary parasitology (01-07-2024)“…The nematode Haemonchus contortus is, as a parasite, responsible for most mortality of small ruminants, causing significant economic losses. Numerous…”
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Methyl jasmonate promotes the transient reduction of the levels of 2-Cys peroxiredoxin in Ricinus communis plants
Published in Plant physiology and biochemistry (01-06-2004)“…Jasmonates are signaling molecules that play a key role in the regulation of metabolic processes, reproduction and defense against insects and pathogens. This…”
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