Search Results - "Sölver, Ellen"
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Development of a Synthesis of Kinase Inhibitor AKN028
Published in Organic process research & development (19-10-2018)“…The novel tyrosine kinase inhibitor AKN028 has demonstrated promising results in preclinical trials. An expedient protocol for the synthesis of the compound at…”
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Development of a Safe Process for Manufacturing of the Potent Anticancer Agent Melflufen Hydrochloride
Published in Organic process research & development (21-06-2019)“…Melflufen is a novel cytostatic currently in phase III clinical trials for treatment of multiple myeloma. Development of a process suitable for production is…”
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Stereoselective Synthesis of Monoamine Reuptake Inhibitor NS9544 Acetate
Published in Organic process research & development (18-03-2011)“…(−)-3-(2-Benzothienyl)-8-H-8-azabicyclo[3,2,1]oct-2-ene acetate, NS9544 acetate, is a candidate drug intended to treat pain and other CNS disorders. In the…”
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A Large Scale Process for the Preparation of Thymitaq
Published in Organic process research & development (21-11-2008)“…The large scale manufacturing of the anticancer agent 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3H-quinazolin-4-one dihydrochloride (thymitaq) from…”
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Limited transmission of drug-resistant HIV type 1 in 100 Swedish newly detected and drug-naive patients infected with subtypes A, B, C, D, G, U, and CRF01_AE
Published in AIDS research and human retroviruses (01-11-2003)“…The prevalence of genetic drug resistance in newly diagnosed HIV-1 cases and potential subtype-specific mutation patterns were studied. Samples from 100 newly…”
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Specific synthetic peptides for detection of and discrimination between HIV-1 and HIV-2 infection
Published in Journal of acquired immune deficiency syndromes (1988) (1991)“…A panel of highly purified synthetic oligopeptides representing defined parts of the gag and env proteins of HIV-1 and HIV-2 were used as antigens in ELISA for…”
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