Search Results - "So, Tsz Y."
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Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment
Published in Disease models & mechanisms (01-02-2022)“…Anti-cancer properties of statins are controversial and possibly context dependent. Recent pathology/epidemiology studies of human lung adenocarcinoma showed…”
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Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development
Published in Cell reports (Cambridge) (23-06-2020)“…The tumor microenvironment (TME) consists of different cell types, including tumor-associated macrophages (TAMs) and tumor-associated fibroblasts (TAFs). How…”
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Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells
Published in Nature biotechnology (14-08-2024)“…Monoclonal antibodies are increasingly used to prevent and treat viral infections and are pivotal in pandemic response efforts. Antibody-secreting cells (ASCs;…”
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Intratumoral antigen signaling traps CD8 + T cells to confine exhaustion to the tumor site
Published in Science immunology (24-05-2024)“…Immunotherapy advances have been hindered by difficulties in tracking the behaviors of lymphocytes after antigen signaling. Here, we assessed the behavior of T…”
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